Mismatch Repair Genes <i>Mlh1</i> and <i>Mlh3</i> Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches by Ricardo Mouro Pinto (207712)

Efficacy of dexamethasone and ACTH in drug resistant pediatric epilepsy. by Nicola Marchi (4967)

“…(<b>B</b>) Mosaic plot showing the correlation between etiology of epilepsy and likelihood of a response ≥50%. Note that etiology did not always predict response. …”

Different simulation protocols of increased firing and depressed activity. by Isabelle Ayumi Spühler (444465)

“…After 4 sec, 50% of release sites increase or decrease their release for a short time window to simulate phasic firing of the dopaminergic neurons. …”

Sensitivity of biomass and cumulative harvest to magnitude of climate impacts under alternative management strategies. by Jameal F. Samhouri (10136090)

“…<p>Outcomes of implementing fixed versus annual climate adaptive harvest management strategies on mean population biomass and cumulative harvest over 50-year simulations in a population subject to a gradual decrease or increase in carrying capacity <b>(a, d)</b>, productivity <b>(b, e)</b>, and both carrying capacity and productivity <b>(c, f)</b>. …”

Percent differences between the fixed and climate adaptive harvest management strategies in mean biomass and cumulative harvest at different time intervals in the simulations. by Jameal F. Samhouri (10136090)

“…<p>Percent differences in mean biomass and cumulative harvest between the fixed and climate adaptive harvest management strategies for 16-year time intervals throughout the 50-year simulations in populations subject to a gradual decrease in (a) carrying capacity, (c) productivity, (e) both carrying capacity and productivity, or a gradual increase in (b) carrying capacity, (d) productivity, (f) both carrying capacity and productivity. …”

HRas^V12 expression in epithelial cells induces cell shape and genetic changes associated with EMT <i>in vivo</i>. by Christina M. Freisinger (246174)

“…(B–C) Fluorescent Z stack projections of HRas^WT and HRas^V12 expressing epithelial cells (magenta) in the trunk region of 3.5 dpf larvae (illustrated in A). (D–E) Lateral fluorescent images, from live imaging, of 3.5 dpf embryos co-expressing GFP-H2B to label the nuclei and either HRas^WT (D) or HRas^V12 (E) at 0, 2 hr and 4 hr time points. …”

Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Neuronal complexity was greatly reduced by neuronal GALC depletion. by Conlan Kreher (13001753)

“…<p>(<b>A, B</b>) Double transgenic mice of 1-year-old <i>Syn1Cre; Galc flox/−;</i> Thy1.1-YFP shows that a decrease in the density of YFP neurons/axons in the brainstem and cerebellum, compared to control (<i>Galc +/−;</i> Thy1.1-YFP). …”

Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_3_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

The changes in plasma and cardiac corin in early phase of AMI. by Dong Wang (73290)

“…(B) Corin cardiac transcript levels in infarct hearts assessed by qRT-PCR analysis in non-MI group and at the indicated time points post-MI. …”

AZ2.0 Scripts & Code by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the percentage repeat, over the earlier assembly (v1.0). …”

Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia-1 by John K Neubert (30743)

“…Animals pretreated with vehicle (0.25% Tween-80, PBS 50 μl, N = 10) had a significant decrease in their heat withdrawal latency (P < 0.05, 1 way RM-ANOVA) following induction of inflammation.…”

Behavioral stress fails to delay surgical castration-induced involution and apoptosis in mice prostates. by Sazzad Hassan (454373)

“…<p><b>A)</b> Castration-induced prostate involution. …”

Watermelon cultivation in the semi-arid irrigated with different heights of treated domestic sewage by Vinicius Couto Salgado (5668235)

“…We observed an increase in the cation exchange capacity and a decrease of the soil pH in all the treatments. …”

Technical and economic viability of rendering mortar produced with incorporation of ornamental rocks residue by Luís Gustavo Fiorese Vinco (4653883)

“…Regarding production costs, there was a decrease in all the mixtures with the addition of ORRC. …”

Nonlinear mfVEP. Average waveforms at No Diet (black), after the DHA-rich (red) and EPA-rich (EPA) supplementations (blue) for the first order kernel (K1) and for the first two sli... by Isabelle Bauer (192853)

“…The decrease in amplitude at N1 (50–60 ms) and reduction at P1 (around 100 ms) following the EPA-rich supplementation when compared to No Diet and DHA was most prominent.…”