Image2_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.JPEG by Athanasios Chamzas (19699780)

“…The estimated apparent clearance was 13.7 L/h for a typical patient weighing 70 kg and at 30% hematocrit, demonstrating a 40% decrease in clearance compared to other patient populations. …”

DEK overexpression in HNSCC cells increases glycolytic end products and TCA cycle intermediates. by Marie C. Matrka (735282)

“…(E-F) The bucket intensity of metabolites in the unconditioned media (dashed red line) were compared to R780 (grey) and R-DEK (black) conditioned media samples to identify metabolites decreased (E) and those increased compared to control unconditioned media (F). …”

Misexpression of triad proteins and expansion of the T-tubule compartment in <i>Ehd1-</i>heterozygous muscle. by Alexis R. Demonbreun (790667)

“…(B) Junctophilin 2 (JP2) protein levels were decreased 13-fold in <i>Ehd1+/-</i> quadriceps muscle compared to wildtype controls. …”

TF-specific motif turnover drives TF binding divergence. by Mathilde Paris (17385)

The Feedback Resistor is Relatively Robust to Molecular Noise by Leor S Weinberger (274196)

“…Trajectories are direct Monte-Carlo simulations of the chemical master equation for <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050009#pbio-0050009-e001" target="_blank">Equation 1</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050009#pbio-0050009-e001" target="_blank">2</a>. …”

Checkpoint, recombinational repair and mitochondrial functions are required for doxorubicin resistance in diploid yeast strains. by Tammy J. Westmoreland (38006)

“…(E) Isogenic respiratory competent and petite WT, <i>ccr4Δ</i> and <i>pop2Δ</i> strains were grown in liquid YPD and serially diluted in 96 well plates as described in panel A. …”

Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice by Miroslava Anderova (155561)

“…Similarly, evaluation of relative α changes showed a significantly smaller decrease in α-syntrophin knockout mice only during severe pathological conditions, but not during mild stimuli. …”

Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx by Akihiro Kambara (10006775)

“…The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”

Table1_Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients.XLSX by Gaurav Tripathi (3163251)

“…Post therapy, 62 plasma metabolites (12 upregulated and 50 downregulated, FC±1.5, p < 0.05) differentiated nonresponders from responders and highlighted a significant increase in the steroid and histidine metabolism and significant decrease in tryptophan metabolism and ascorbate and pyruvate metabolism in the nonresponders. …”

Partial silencing of GFP requires both EhRNaseIII and ScaAgo1. by Justine M. Pompey (268775)

“…FACS histogram of GFP fluorescence in the indicated strains show a decrease in GFP fluorescence in strain expressing EhRNaseIII using the strong GFP silencing hairpin but only in the strain expressing ScaAgo1. …”

datasheet1_In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.docx by Dahara Keyse Carvalho Silva (9774635)

“…In vitro incubation with LASSBio-1386 reduced the percentage of Leishmania-infected macrophages and the number of intracellular parasites (EC₅₀ = 9.42 ± 0.64 µM). Also, in vivo treatment of BALB/c mice infected with L. amazonensis resulted in a decrease of lesion size, parasitic load and caused histopathological alterations, when compared to vehicle-treated control. …”

Datasheet1_Hyperbaric effects on heart rate in professional SCUBA divers in thermal water.pdf by Luigi Fattorini (19758798)

Retinal histology examination after 10 weeks of ocular hypertension. by Nicolás Belforte (328093)

“…Scale bar: Upper panel  =  50 µm; Middle panel  =  50 µm. Data are the mean ± SEM (n = 5 animals per group). * p<0.05, ** p<0.01 vehicle injected eyes without ischemia pulses (sham), a: p<0.05, b: p<0.01 versus CS-injected eyes without ischemia pulses (sham), by Tukey's test. …”

Effects of the ambient temperature on the behavioral responses. by Ivanne Pincedé (270921)

Non-Temperature Induced Effects of Magnetized Iron Oxide Nanoparticles in Alternating Magnetic Field in Cancer Cells by Sudath Hapuarachchige (2203699)

Allelopathic Effects of Different Plant Water Extracts on Yield and Weeds of Wheat by M. NAEEM (5862101)

“…In this study, mixtures of allelopathic water extracts of sorghum + sunflower and sorghum + sunflower + mulberry were sprayed each at 12, 15, 18 and 21 L ha-1 at 40 and 55 days after sowing in wheat to control wild oats (Avena fatua), little seed canary grass (Phalaris minor), lamb’s quarters (Chenopodium album) and swine cress (Coronopus didymus). A synthetic herbicide Affinity 50 WP (Carfentrazone-ethyl 0.75% + Isoproturon 50% applied at 1000 g a.i., ha-1) and a weedy check were kept as a control treatment. …”

Self-Powered Biosensing System with Multivariate Signal Amplification for Real-Time Amplified Detection of PDGF-BB by Futing Wang (14851840)

A mitotic collapse resulting in sustained MPF activity during human cytomegalovirus infection requires APC/C subunit degradation. by Scott S. Terhune (8677500)

“…<b>(E)</b> Simulated increase in CDH1P (<i>k</i>′_<i>r</i>11) induces a collapse with elevated APC/CT yet loss of MPF, PTTG1, CCNB1 and LMNAP. …”

Video 1_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Massively Parallel Implementation of Steered Molecular Dynamics in Tinker-HP: Comparisons of Polarizable and Non-Polarizable Simulations of Realistic Systems by Frédéric Célerse (6710519)

“…Of course, one would like to use all types of force fields (FF) ranging from classical ones to more advanced polarizable models using point induced dipoles and distributed multipoles such as AMOEBA. …”