Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…We found a significant decrease in annual hospital mortality over the study period [odds ratio(OR): 0.92 per year, 95% CI 0.88-0.96, P<0.001]. …”

Changes of the normalized volume V/V₀ in glioblastoma cell lines in response to sucrose- and inositol-substituted solutions of different osmolalities (LHS and RHS column... by Simon Memmel (518138)

“…Each data point represents the mean ± SE of 50–120 individual cells. Continuous curves in <i>A</i> show best least-square fits of the Lúcio-model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087052#pone.0087052-Lcio1" target="_blank">[50]</a> to the data. …”

Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif by Yuxiao Zheng (8334027)

“…Background<p>Renal cell carcinoma (RCC) progression is closely linked to dysregulation of the ubiquitin-proteasome system, particularly aberrant ubiquitination processes governing protein degradation and cell cycle control. As a pivotal E3 ubiquitin ligase, COP1 mediates substrate-specific ubiquitination to regulate protein stability. …”

Data_Sheet_1_The burdens of poverty during the COVID-19 pandemic.PDF by Julia Petersen (14168841)

Merlin negatively regulates SC NPC growth and glial differentiation in a Rac1- and ErbB2-dependent manner. by Cynthia Garcia (562261)

“…(<b>B</b>) Pharmacologic Rac1inhibition decreases <i>Nf2</i>−/− SC NPC neurosphere diameters (Vehicle: WT vs. …”

K_eq and Φ of the α subunit. by Pallavi A. Bafna (271514)

“…M2 residues T244, L251 and E262 face the lumen of the pore. <i>Left,</i> Residues colored according to the range for the fold-change in K_eq: >1000-fold (blue), 10–1000 fold (cyan) and <10-fold (grey) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0002515#pone-0002515-t002" target="_blank">Table 2</a>). αM2-cap residues experience large energy differences (‘move’) between C and O, whereas many mutants of residues near the cytoplasmic limit of the channel are iso-energetic, which may indicate relatively smaller structural changes. …”

Trypanosoma cruzi induces changes in gene expression of glucocorticoid and prolactin receptors in CD4⁺CD8⁺ cells and alters their sensitivity to GC-induced ap... by Ailin Lepletier (328461)

The stomatal lineage bHLHs have the potential to bind nucleosomal DNA and induce chromatin remodeling. by Ao Liu (481251)

“…<b>(D)</b> Changes in nucleosome occupancy (MNase-seq signal) at nucleosomal MUTE peaks (left) and random peaks (right) after ectopic, EST-induced, MUTE expression. <b>(E)</b> Example of a decrease in nucleosome signal at a MUTE binding site upon MUTE induction. …”

Gene expression profile of <i>Pcgf5</i>-deficient HSPCs. by Sha Si (2635147)

“…The statistical significance of the overlaps between the two gene groups is indicated. (E) Expression of <i>Pcgf</i> genes in WT LSK cells and GMPs in RPKM.…”

ATP homeostasis is maintained by AMPK-FOXO-CKB pathway in HEK293 cells under oxidative stress conditions. by Nan Zhang (46264)

“…<b>(b)</b> Knockdown of <i>CKB</i> or <i>AMPKα1</i>/<i>α2</i> mRNA expression increased the fold of ATP decrease caused by paraquat treatment for 24h in HEK293 cells. …”

Neutralization of plasmas against spike-pseudotyped lentiviral particles. by Allison J. Greaney (11046384)

“…Right: summary plot of the geometric mean across cohorts of the fold-decrease in neutralization compared to Delta spike (left axis) or D614G spike (right axis). …”

Data_Sheet_1_Characterization of a Dopamine Transporter and Its Splice Variant Reveals Novel Features of Dopaminergic Regulation in the Honey Bee.pdf by Vicky Zhang (7617218)

Attachment domains within MgpB are Located within the Proximal Conserved C-terminus and Share Homology with the Attachment Domain of the <i>M</i>. <i>pneumoniae</i> P1 Protein. by Stefanie L. Iverson-Cabral (797308)

Novel Radiotracer for ImmunoPET Imaging of PD‑1 Checkpoint Expression on Tumor Infiltrating Lymphocytes by Arutselvan Natarajan (1234197)

CD36 and Fyn Kinase Mediate Malaria-Induced Lung Endothelial Barrier Dysfunction in Mice Infected with <i>Plasmodium berghei</i> by Ifeanyi U. Anidi (446498)

When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail - Fig 3 by Alba Bernini (7512641)

“…In panel B, seed farms are ranked in decreasing order of the median total epidemic size they generated and each x-axis point represents a position in the rankings. …”

Analysis of mRNA levels of several candidate genes in relation to BMD levels. by Patricia Sarrión (552152)

“…<p>(<b>A</b>–<b>D</b>) Trend of correlation between Z-score values and gene expression levels of <b>(A)</b><i>TWIST1</i>, (<b>B</b>) <i>IL6R</i>, (<b>C</b>) <i>DLX3</i> and (<b>D</b>) <i>PPARG</i>. (<b>E</b>) One of the HBM samples presented an expression level of <i>SOX6</i> 5-fold decreased in relation to the mean of five control individuals. …”

C1 shows similar results on macrophages as for microglia and does not interfere with cell activity, proliferation, and cell death are not affected in non-stimulated conditions. by Philipp Jordan (9364068)

“…<b>d)</b> When stimulated with 1 μg/mL LPS (for 48 hours, using the same protocol as referred above C1 caused a dose independent decrease in cell activity for all 3 concentrations of C1 (0.025μM: 78.47 ± 31.61%, p = 0.0245; 0.25μM: 69.31 ± 36.50%, p = 0.001; 2.5μM: 66.48 ± 31.17%, p<0.001) in comparison to the positive control (100 ± 4.74%) and when cells were treated with 2.5 μM C1 there was a reduction of the cell activity also when compared to the DMSO control (p = 0.0310). …”

Assessment of SnO2 nanoparticles' impact on local Pichoclorum atomus growth performance, cell morphology and metabolites content by Bounnit, Touria

“…The current study investigates the ecotoxicity of SnO2 nanoparticles on a local marine algae isolate. Five different concentrations (1, 5, 25, 50 and 100mg/L) were tested and the culture was followed for 72h. …”
Get full text
Get full text

Antiangiogenic activity of photobiomodulation in experimental model using chorioallantoic embryonic membrane of chicken eggs by Lays Fernanda Nunes Dourado (6098738)

“…We treated the negative control group with 50 μl phosphate-buffered-saline (pH 7.4) and the positive control group (Beva) with 50 μl bevacizumab solution (Avastin, Produtos Roche Químicos e Farmacêuticos, S.A., Brazil). …”