TCR-like Fabs Bind Cognate pMHC with Nanomolar Affinity. by Keith R. Miller (141522)

“…Each binding curve represents a different concentration of pMHC beginning at 200 nM and decreasing to 1.5 nM in 2 fold dilutions. No binding was observed for either Fab binding non-cognate pMHC molecules up to 400 nM.…”

Targeted expression of TeTxLC, Shi, Kirand Glued-DN affects the architecture of the CSDn by Bidisha Roy (37349)

“…RN2--CD2-FRT-Gal4, UAS-/UAS-showing greatly increased dendritic branches within the ipsilateral lobe (arrows in (e)) and modest decrease in contralateral terminals (k). …”

Data_Sheet_1_Causal Associations of Urate With Cardiovascular Risk Factors: Two-Sample Mendelian Randomization.docx by Thitiya Lukkunaprasit (9548637)

“…</p>Results<p>The statistically driven approach showed significant causal effects of urate on HDL-C and triglycerides using four of the six MR methods, i.e., every 1 mg/dl increase in genetically predicted urate was associated with 0.047 to 0.103 SD decrease in HDL-C and 0.034 to 0.207 SD increase in triglycerides. …”

The effects of Nodal on proliferation and apoptosis are dependent on activation of the type 1 receptor (ALK4/7). by Daniela F. Quail (123286)

“…(E) PCR analysis demonstrating that treatment of MDA-MB-231 cells with 10 µM SB431542 causes a significant increase in <i>BAX</i> expression (n = 3, p = 0.002), and (F) a significant decrease in <i>BCL2</i> expression (n = 3, p = 0.022), indicative of elevated apoptosis compared to vehicle controls. …”

Reduced Lung Inflammation in TLR2 KO Mice 72 Hours after Infection by W. Joost Wiersinga (33895)

“…TLR2 KO mice that survived the experiment shown in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0040248#pmed-0040248-g003" target="_blank">Figure 3</a>A were examined 6 wk after inoculation; as expected, they showed decreased organ inflammation as compared to the 72 h time point The abscesses that were still present were encapsulated (H). …”

ENOblock does not inhibit the conversion of 2-PGA to PEP as measured by ³¹P NMR Experimental conditions were the same as for the experiments presented in Fig 2, except t... by Nikunj Satani (3605696)

“…(<b>a)</b> The 2-PGA peak (3.5 ppm, <b>e</b>) was stable for >24hrs in the absence of enzyme, but rapidly decreased with a concomitant increase in the PEP peak (-1ppm, <b>e</b>) in the presence of 10 nM recombinant hENO2. …”

Extracellular acidification delays neutrophil apoptosis and reduces caspase 3 activation. by Shannan Cao (792360)

“…Purified neutrophils were labeled with FITC-annexin V and PI after cultured for indicated time and detected by flow cytometer. (D,E) pH changed from acid to neutral at either the 4^th hour(D) or the 12^th hour(E) of cell culture will accelerate the neutrophil death. …”

Directed evolution of HIV-1 to utilize CD4^low target cells. by David Beauparlant (3491435)

“…<b>(E)</b> Adaptation to CD4^low target cells results in high resistance to CD4 inhibitor compared to wild type HIV-1 isolates. Comparison of IC50 of CD4-blocking DARPin 55.2 against 41 wild-type HIV-1 strains from different clades (black dots, see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006255#ppat.1006255.s003" target="_blank">S3 Table</a> for details on virus panel and individual IC50 values) and the CD4^low adaptation virus panel (colored dots, see legend) probed by Env pseudovirus infection on TZM-bl cells. …”

IAA application on <i>pin1</i> meristem leads to local tissue softening and pectin de-methyl-esterification in sub-epidermal tissues. by Siobhan A. Braybrook (388465)

“…Each pixel in a rigidity map corresponds to the E_A value obtained from one indentation point. …”

Stimulus and results of Experiment 4 ‘Pre-exposure in binocular rivalry’. by Maartje Cathelijne de Jong (334147)

“…We used the paradigm presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030595#pone-0030595-g001" target="_blank">figure 1B</a>, with the intermittent viewing period lasting either 0.5 or 2.5 minutes and the test period lasting 50 seconds. …”

Kinetic characterization of GK and its inhibition by GKRP. by Magdiel Salgado (553127)

“…As has been reported in hepatocytes, GKRP inhibits glial GK in a dose-dependent manner, resulting in a median inhibitory concentration (IC₅₀) of 0.28 mM. …”

Ivermectin uptake and infection status (n = 270). by Mwanahawa I. Mshana (15460720)

DataSheet1_Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.pdf by Tianye Li (9759056)

“…Most importantly, a marked decrease in nuclear β-catenin was observed in cells that received cisplatin treatment. …”

Mechano-Responsive, Tough, and Antibacterial Zwitterionic Hydrogels with Controllable Drug Release for Wound Healing Applications by Kun Fang (619812)

SEM images with different water glass content. by Chenhao Li (822769)

Image 2_Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.tif by Fengqin Li (126568)

“…When autophagy levels were reduced using NAC and 3-MA, a corresponding decrease in TCID₅₀ was observed. …”

Image 6_Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.jpg by Fengqin Li (126568)

“…When autophagy levels were reduced using NAC and 3-MA, a corresponding decrease in TCID₅₀ was observed. …”

Table1_Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.PDF by Tianye Li (9759056)

“…Most importantly, a marked decrease in nuclear β-catenin was observed in cells that received cisplatin treatment. …”

DataSheet2_Synthesis, docking studies, biological activity of carbon monoxide release molecules based on coumarin derivatives.ZIP by Huapeng Liu (7360361)

“…Moreover, complex 5 caused a decrease of mitochondrial membrane potential and effectively induced ROS production against MDAMB231 cells. …”

DataSheet1_Synthesis, docking studies, biological activity of carbon monoxide release molecules based on coumarin derivatives.DOCX by Huapeng Liu (7360361)

“…Moreover, complex 5 caused a decrease of mitochondrial membrane potential and effectively induced ROS production against MDAMB231 cells. …”