Image_1_Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.JPEG by Juan Chen (61123)

“…Covariates associated with voriconazole plasma concentrations and dose requirements were adjusted by using generalized linear mixed-effect models.</p>Results<p>A total of 682 voriconazole steady-state trough concentrations from 91 Chinese pediatric patients were included. …”

Mobility Competitiveness and Security: Expatriate Perspectives from Qatar by Ewers, Michael Christopher

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Length-dependent activation in NF trabeculae (<i>n</i> = 9) vs. failing trabeculae with no hypothyroidism (FNH; <i>n</i> = 9) and failing trabeculae with hypothyroidism (FH; <i>n</... by Nancy S. Saad (2615341)

“…<b>(E)</b> RT50 decreased as muscles were shortened from L₁₀₀ to L₈₅ and the degree of shortening was much obvious in NF group. …”

Sound evoked cortical activity across vigilance states before and after NOE. by Linus Milinski (10532121)

“…Sounds were one octave narrow band noise (NBN) bursts centred at 1, 4, 8, and 16 kHz, at a stimulus level of 40, 50, 60, and 65 dB SPL, with a duration of 820 ms that included a silent gap of 38 ms. …”

Image_1_Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita.TIF by Balint Kovacs (8294496)

“…In contrast to the antibody-transfer-induced EBA model, individual targeting of FcγRIII or FcγRIV decreased ROS release to 50%. Combined FcγR blocking abrogated ROS release from BM neutrophils. …”

DataSheet1_Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular... by Lingfei Lu (5400374)

“…Molecular docking results showed that kaempferol, triptolide, nobiletin, and schottenol had a strong binding ability to PTGS2 and RELA. Furthermore, the in vitro experiments confirmed that LTD effectively decreased the expression of PTGS2, NF-κB, JNK, and AKT in the HG-induced DKD model.…”

Mosquito-Disseminated Insecticide for Citywide Vector Control and Its Potential to Block Arbovirus Epidemics: Entomological Observations and Modeling Results from Amazonian Brazil by Fernando Abad-Franch (127663)

“…We tested mosquito-disseminated PPF in Manacapuru, a 60,000-inhabitant city (~650 ha) in Amazonian Brazil.…”

Table_1_Comprehensive Multi-Omics Identification of Interferon-γ Response Characteristics Reveals That RBCK1 Regulates the Immunosuppressive Microenvironment of Renal Cell Carcinom... by Wenhao Xu (2302681)

“…Besides, immunohistochemistry staining showed significantly elevated RBCK1 expression in tumors (n = 50) compared with kidney samples (n = 40) from a real-world cohort, Fudan University Shanghai Cancer Center (FUSCC, Shanghai). …”

Data_Sheet_1_Functional Exhaustion of Type I and II Interferons Production in Severe COVID-19 Patients.docx by Caroline Ruetsch (9691565)

“…In vitro treatment with type IFNα restored type IFNγ secretion in COVID-19 patients while the secretion of pro-inflammatory cytokines IL6 and IL1β remained stable or decreased, respectively. These results (a) demonstrate a functional exhaustion of both innate and adaptive immune response in severe forms of COVID-19; (b) identify IFNα and IFNγ as new potential biomarkers of severity; and (c) highlight the importance of targeting IFNs when considering COVID-19 treatment in order to re-establish a normal balance between inflammatory and Th1 effector cytokines.…”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…</p>Methods<p>CorPuScula (Coronary, Pulmonary and Sanguis) is a longitudinal, repeated-measure panel study conducted in 2000–2002 in Munich, Germany including 52 seniors (58–94 years old) with 899 observations and 50 children (6–10 years old) with 925 observations. …”

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children by Liusheng Huang (610226)

“…Similarly, peak concentration was decreased by 50% (p = 0.07) for artemether and 36% (p = 0.01) for dihydroartemisinin. …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…</p>Methods<p>CorPuScula (Coronary, Pulmonary and Sanguis) is a longitudinal, repeated-measure panel study conducted in 2000–2002 in Munich, Germany including 52 seniors (58–94 years old) with 899 observations and 50 children (6–10 years old) with 925 observations. …”

LPS triggered chemotactic signaling through fAR1. by Miao Pan (5285834)

“…On the right, structural modeling and computational docking predict that the extracellular domain of fAR1 folds into a VFT structure functioning as the binding site for FA moiety (green). …”

Proxy-based paleoclimate series for the last 5000 years. by David Kaniewski (218243)

“…Interval of high (low) Cyperaceae pollen percentages are interpreted in terms of increased (decreased) Nile flow; (<b>g</b>) fluctuations of the δ¹⁸O speleothem scores from Soreq Cave, Israel, for the last 3600 years <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071004#pone.0071004-BarMatthews1" target="_blank">[70]</a>. …”

Table 1_Multicenter epidemiology of Stenotrophomonas maltophilia bloodstream infections in Indian ICUs: building digital surveillance network.pdf by Parul Singh (191877)

“…Mortality was highest in secondary BSIs (60%), followed by CLABSIs (50.3%) and non-CLABSIs (36.4%). The median ICU stay for CLABSI patients was 21 days. …”

Performance of the model with the inhibitory V0_D pathways removed. by Yaroslav I. Molkov (542831)

“…Decreasing <i>α</i> causes two bifurcations: (i) transition from symmetric alternations of flexor activity, i.e. with a phase difference of Δ<i>φ</i> = 0.5, to alternations with a phase difference of Δ<i>φ</i> ≠0.5 at X₇ and then (ii) from alternation to synchronization of flexor activity at X₆. …”

Table_1_Visual Feedback Modulates Aftereffects and Electrophysiological Markers of Prism Adaptation.DOCX by Jasmine R. Aziz (6195440)

“…Adaptation is hypothesized to occur through two processes: strategic recalibration, a rapid self-correction of pointing errors; and spatial realignment, a more gradual adjustment of visuomotor reference frames that produce prism aftereffects (i.e., reaching errors upon glasses removal in the direction opposite to the visual shift). …”

Line profile analyses of gekkotan eggshells. by Seung Choi (3542693)

“…(E) <i>Correlophus ciliatus</i>. The hatched rectangle marks the crack. …”

Curcumin affects the brain amyloid deposition histology patterns as a function of <i>Drosophila</i> genotype. by Ina Caesar (185701)

“…DAPI staining from regions with widespread p-FTAA-positive aggregates were decreased. (K–O) Aβ_{1–42 E22G} expressing flies at day 0, day 5, and day 10, showed a spot-like staining from both p-FTAA and the Aβ specific antibody, but a weaker p-FTAA staining was apparent (c.f. …”

Cerebellar pathology in FTgpi mice. by Paolo Dametto (253415)

“…(<b>E</b>) Cerebellar frozen sections were stained with DAPI (blue), Iba1 (yellow) and TUNEL (purple) to reveal nuclei, fragmented DNA, and microglia respectively. …”