Quantitative secretomics allows comparison of individual VgrG dependence across multiple T6SS substrates and reveals a new VgrG2-specific effector. by Francesca R. Cianfanelli (2856026)

“…Points show mean ± SEM (n = 4). Inset: genetic arrangement of <i>SMDB11_0927–0929</i>, where <i>SMDB11_0927</i> encodes the new lipase-like effector, Slp.…”

Nature of Decahydro-<i>closo</i>-decaborate Anion Reorientations in an Ordered Alkali-Metal Salt: Rb₂B₁₀H₁₀ by Mirjana Dimitrievska (1494430)

“…This result is consistent with previous NMR data for ordered monoclinic Na₂B₁₀H₁₀, which also pointed to two types of anion reorientational motions. …”

Nature of Decahydro-<i>closo</i>-decaborate Anion Reorientations in an Ordered Alkali-Metal Salt: Rb₂B₁₀H₁₀ by Mirjana Dimitrievska (1494430)

“…This result is consistent with previous NMR data for ordered monoclinic Na₂B₁₀H₁₀, which also pointed to two types of anion reorientational motions. …”

Domain structure of the <i>M. circinelloides</i> Ago proteins. by María Cervantes (5655781)

“…Arrows indicate the amino acids whose mutations led to a decreased RNA-binding efficiency <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0069283#pone.0069283-Lingel1" target="_blank">[14]</a>. …”

Design of an inducible CRISPRi gene-silencing system for <i>S</i>. <i>mutans</i>. by Robert C. Shields (8551326)

“…As the xylose concentration was decreased, data points change from a dark to a light blue color. …”

Information S1 - Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor by Akiko Murakami (515972)

“…Treatment with YC-1 significantly decreased the number of HIF1α-positive cells in a dose-dependent manner. …”

Knock out VGLL4 in valvar endothelial cells leads to hypertrophy and compromised heart function on later stage. by Wei Yu (43094)

“…<p>(A) Gross front view of hearts from 9-month-old <i>Tie2</i>^<i>Cre+</i><i>;Vgll4</i>^<i>fl/-</i> and <i>Vgll4</i>^<i>fl/-</i> control hearts. …”

Salinity and nitrogen removal rate. by Valentin Faust (13176389)

Larvicidal and macrofilaricidal efficacy of Closantel and Morantel against mosquito larvae and <i>Setaria digitata</i> nematodes by Megan Hall (506400)

“…While malaria incidence in India has decreased by nearly 50% in recent years, India holds 66% of the WHO SEA region’s malaria burden (World Malaria Report, 2023, Singh et al., 2024). …”

Microsatellite Instability and Mistmatch Repair protein analysis by Salvador J. Diaz-Cano (100072)

“…<p>Microsatellite Instability Testing in CRC and Interpretation</p> <p>Microsatellite instability is a type of mutation that occurs in microsatellite regions (short polymorphic DNA segments) by nucleotide addition (increased size) or nucleotide loss (decreased size) in the repeats. …”

Molecular and Peritoneal Microvascular Changes Cause Peritoneal Membrane Dysfunction by Uremia-Related Mechanisms by Zakaria, El-Rasheid

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Peg13 attenuates the sevoflurane-induced NSC damage. by Yunfeng Jiang (2589892)

“…Transduction with OE-Peg13 at MOI of 10 increased Peg13 transcripts by 1.8 folds, determined by qRT-PCR. G, H. Peg13 over-expression recovered the sevoflurane-decreased neurosphere formation in NSCs. …”

Reduced control model M4: Normative evidence accumulation. by Veith Weilnhammer (2909060)

“…History-congruent amounted to 50.73% ± 0.07% of trials (in blue). As in the full model, the no-oscillation model showed a significant bias toward perceptual history T(4.32×10³) = 9.94, <i>p</i> = 4.88×10⁻²³; upper panel). …”

<i>Cobl</i> KO mice fail to show repair of the dendritic arborization defects caused by MCAO in both layer II/III and layer V neurons of the ipsilateral hemisphere. by Yuanyuan Ji (455424)

“…Note that dendritic branching points (<b>E</b>), dendritic terminal points (<b>F</b>), total dendritic tree length (<b>G</b>), and Sholl intersections (<b>H-J</b>) were all decreased at 24 hours after MCAO and that, in contrast to WT animals (<b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001399#pbio.3001399.g005" target="_blank">Fig 5</a></b>), none of these phenotypical parameters recovered during the days after MCAO in <i>Cobl</i> KO mice. …”

WFS1 deficiency leads to impaired neuronal development. by Michal Cagalinec (3151077)

“…(D–F) WFS1 deficiency retards growth of the longest axon (D) and growth of the axonal tree (E) and decreases the number of axon tips (F). (G) Survival of WFS1-deficient neurons is decreased when compared with control neurons (<i>n</i> = 61–62 individual dishes from 17 independent sister cultures at DIV 6–11). …”

Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Connecting Protein Conformation and Dynamics with Ligand–Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking by Mark Kastantin (1514023)

“…By controlling FN structure and dynamics through tuning surface chemistry, we found that as the conformational and translational dynamics of FN increased, the rate of binding, particularly to folded FN, and stability of the bound FN−α_vβ₃ complex decreased significantly. …”

Histopathological scores and histopathologies of EAU mice. by Kayo Suzuki (166737)

“…Furthermore, these scores were further decreased when treated by inhibiting both Ang2 and VEGFA (i.e., anti-Ang2 antibody with anti-VEGFA antibody treatment group and anti-Ang2/VEGFA bispecific antibody treatment group) (P<0.01). …”

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity by Mei-Ling Yang (3625355)

Initial Mutations Direct Alternative Pathways of Protein Evolution by Merijn L. M. Salverda (228413)

“…We found that a combination of decreased enzymatic activity and lower folding cooperativity underlies negative sign epistasis in the clash between key mutations in the common and deviating lines (Gly238Ser and Arg164Ser, respectively). …”