A High Force of <i>Plasmodium vivax</i> Blood-Stage Infection Drives the Rapid Acquisition of Immunity in Papua New Guinean Children by Cristian Koepfli (191306)

“…In this cohort, <i>P. vivax</i> episodes decreased three-fold over the age range of 1–4.5 years.…”

HEN1 is required for miRNA stability. by Vengamanaidu Modepalli (4335724)

“…Each dot represents the read counts of an individual miRNA before and after HEN1 knockdown. miRNAs that showed a depletion ≥ two-fold change are indicated in green. The data represent the mean of two independent biological replicates. …”

RAD21 is necessary for ERα binding within the <i>MYC</i> locus but not an exogenous ERE. A) RAD21 silencing abrogates ERα binding upstream of <i>MYC</i>. by Miranda V. McEwan (121381)

“…Cells were treated with vehicle (V) or estradiol (E) for 24 hours before luciferase activity was measured. …”

A set of microphotographs and a graph documenting inhibition of neutrophil migration towards 10 µM CuSO₄ exposed hair cells resulting from co-treatment of 5 dpf Tg(MPX:G... by Natalia Kasica-Jarosz (5328554)

“…The presented values refer to the average number of neutrophils in each group. 100 nM PACAP-38 treatment resulted in a significant, over two-fold decrease in the number of the neutrophils found singly in the area defined by notochord borders and those associated with neuromasts as compared to that determined in the 10 µM CuSO₄-exposed group (one-way ANOVA, Kruskal–Wallis test with Dunn’s post-test, GraphPad Prism 5, <i>p</i> < 0.001). …”

Image_3_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…Additionally, a more than 2-fold increase in secreted Aβ_1−x was observed under the latter two conditions. …”

Image_2_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…Additionally, a more than 2-fold increase in secreted Aβ_1−x was observed under the latter two conditions. …”

DataSheet1_Structural identification of catalytic His158 of PtMAC2p from Pseudozyma tsukubaensis, an acyltransferase involved in mannosylerythritol lipids formation.pdf by Yusuke Nakamichi (1851106)

“…Site-directed mutagenesis of His158 to Ala resulted in more than 1,000-fold decrease in the catalytic activity of PtMAC2p. …”

Image_7_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…Additionally, a more than 2-fold increase in secreted Aβ_1−x was observed under the latter two conditions. …”

Hypocotyl properties under single versus multiple stress conditions in wildtype and <i>bin2-1</i> mutants. by Nils Kalbfuß (14248277)

“…Scanning electron micrographs (A, D) were used to assess cellular parameters. (B, E) hypocotyl cell length. (C, F) hypocotyl cell anisotropy measured in 2D as length/width. …”

Collaboration of Syk kinase and TLR/MyD88 pathways sustain IB degradation and enhance NFB nuclear translocation by Kevin M Dennehy (89097)

“…Numbers above each lane show fold decrease (IB) or increase (cRel) of the relative band intensities of IB and c-Rel, with actin and USF-2 as loading controls, unstimulated control. …”

Image_5_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…Additionally, a more than 2-fold increase in secreted Aβ_1−x was observed under the latter two conditions. …”

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Jun Ding (80820)

“…Both homoplasmies and heteroplasmies show 5-fold higher transition/transversion ratios than variants in nuclear DNA. …”

Refeeding leads to enhancer overshoot with increased LXR footprint and enrichment of the LXR motif. by Noga Korenfeld (19557350)

“…FA, flanking accessibility; FC, fold change; FPD, footprint depth; LXR, liver X receptor; TF, transcription factor.…”

Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation by Bhavapriya Vaitheesvaran (177385)

DepMap essential genes exhibit preferential epigenetic conservation. by Daniel Rud (11432670)

“…<b>C)</b> DepMap essential genes (shRNA log-fold decrease less than -0.4) showed significantly smaller gene PWDs than non-essential genes. …”

KChIP2 KD associates with a relocalization of presenilin 1 away from sarcomeric structures. by Drew M. Nassal (845780)

“…<b>(D)</b> Representative immunostaining for RyR between Ad.GFP (left panel) and Ad.KChIP2 KD (right panel), showing preserved distribution. <b>(E)</b> Average plot profile for presenilin 1 from regions of interest (white boxes) showing the decreased peak intensity at sarcomeres and increased intensity between sarcomeres in Ad.KChIP2 KD (n = 25) compared to Ad.GFP (n = 25) myocytes. …”

HP1a protein levels are reduced and its localization pattern is altered by over-expression of CHD1. by Lakshmi Bugga (393594)

Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals by Hanna Shin (6697529)

Comparative growth rates of cultured marine dinoflagellates in the genus <i>Symbiodinium</i> and the effects of temperature and light by Anke Klueter (365228)

Impact of precipitation and temperature changes on hydrological responses of small-scale catchments in the Ethiopian Highlands by Tatenda Lemann (3187935)

“…Results indicate that runoff reacts disproportionately strongly to precipitation and temperature changes: a 24% increase in precipitation led to a 50% increase in average annual runoff, and an average annual rainfall–runoff ratio that was 20% higher. …”