Pioglitazone Improves Fat Distribution, the Adipokine Profile and Hepatic Insulin Sensitivity in Non-Diabetic End-Stage Renal Disease Subjects on Maintenance Dialysis: A Randomized... by Anne Zanchi (645982)

“…This was associated with a 20% increase in hepatic insulin sensitivity without changes in muscle insulin sensitivity, a 12% increase in HDL cholesterol and a 50% decrease in CRP.…”

Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development—Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Ide... by Katarina Truvé (215968)

“…<i>CAMKK2</i> showed reduced expression in both canine and human brain tumors, and a non-synonymous variant in <i>P2RX7</i>, previously demonstrated to have a 50% decrease in receptor function, was also associated with disease. …”

Data Sheet 1_Assessment of heat-killed E. coli expressing Chikungunya virus E2 protein as a candidate vaccine for dual protection against Chikungunya virus and E. coli.docx by Surajit Patra (18400578)

“…The CHIKV neutralization assay results showed a two-fold decrease in CHIKV TCID50 value after 12 hours and a three-fold reduction after 120 hours. …”

Supplementary file 1_Comparative efficacy of femoral neck system vs. cannulated compression screws in young patients with femoral neck fractures: a systematic review and meta-analy... by Weishuai Zhang (22399933)

“…In addition, the FNS group exhibited a lower incidence of postoperative complications, including urinary tract infections, venous thromboembolism, non-union, screw loosening, and femoral head necrosis [risk ratio (RR) = 1.05, 95% CI: 0.92–1.19, P = 0.50]. …”

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study... by Helena Huerga (109527)

“…Culture in sputum was done for a subset of patients. The diagnostic yield was defined as the proportion of patients with a positive assay result among those with laboratory-confirmed TB. …”

Double immunofluorescent labelling for actin and phosphorylated p44/42 (a) from lumbar DRGs of control, untreated STZ-induced diabetic, and insulin-treated STZ-induced diabetic rat... by Kazuhiro Sugimoto (452376)

“…Neuronal and satellite cell phosphorylated p44/42 (e) fluorescence intensity is significantly increased by 68% in untreated STZ-induced diabetic rats (black bars) compared with control rats (white bars), whereas it is significantly decreased by 50% in insulin-treated STZ-induced diabetic rats (grey bars) compared with untreated STZ-induced diabetic rats. …”

Relative phases A (<i>ψ</i>₁) and B (<i>ψ</i>₂) of the direct and retrograde wave gaits from the simple model. by Yuichi Ambe (3766735)

“…<p>The relative phases are derived with both high stiffness (<i>d</i>* <i>K</i>* = 50)(solid line) and low stiffness (<i>d</i>* <i>K</i>* = 5)(dashed line) for <i>s</i>*/<i>a</i>* = 0.3. …”

<i>fmn</i> mutant flies expressing dTrpA1 or <i>shi</i>^ts showed increased temperature sensitivity compared to control flies. by Taro Ueno (184669)

“…Temperature at which the activity index decreased to 50% of that at 25°C calculated from C. …”

Data_Sheet_1_The Associations of Plasma Carotenoids and Vitamins With Risk of Age-Related Macular Degeneration: Results From a Matched Case-Control Study in China and Meta-Analysis... by Hong Jiang (79543)

“…Plasma concentrations of examined carotenoids and vitamins were significantly lower in patients with AMD than those in controls. After a multivariate adjustment for body mass index, blood cholesterol, and other lifestyle risk factors, higher lutein/zeaxanthin content in plasma was significantly associated with a decreased risk of AMD, and the odds ratio (OR) comparing the top and bottom tertiles was 0.21 (95% CI: 0.05, 0.84; P_trend = 0.024). …”

VEGF-A siRNAs cause upregulation of phosphorylated Thr³⁰⁸-AKT and downregulation of Ang II and AT1R in NRK-52E cells in high glucose. by Xiaoyan Bai (554943)

“…<p>(A) Upregulated pAKT (T308) while (B) no effects on pAKT (S473) in NRK-52E cells mediated by VEGF-A_siRNA#1 and #2 (immunofluorescence, scale bar 50 µm). …”

Data Sheet 1_Brain microvascular endothelial cells differentiated from a Friedreich’s Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly perm... by Frances M. Smith (17770776)

“…In the absence of dysregulated F-actin organization, FA iBMVEC exhibited a loss of 50% ZO-1, 63% Occludin, and 19% Claudin-5 protein expression, along with a disruption in the bi-cellular organization of the latter two proteins. …”

DataSheet1_Temporal Trends in the Incidence and Mortality of Major Reproductive-Related Cancers in Women in Guangzhou From 2010 to 2020: A Joinpoint and Age-Period-Cohort Study.xls... by Suixiang Wang (11086199)

“…</p><p>Conclusion: The ASIRs for cervical and ovarian cancers among women in Guangzhou showed a decreasing trend during the period. The APC model showed mortality for 4 cancers increased with age. …”

Effect of 2% HQ, 0.05% INN and 0.1% TAC on hippocampal 5-HT level and 5-HT_{1A /1B} receptor expression. by Huali Wu (349567)

“…Scale bar = 50μm. (C) IOD values of the expression of 5-HT_1A receptor in CA1 region. …”

DataSheet1_A mechanistic physiologically based model to assess the effect of study design and modified physiology on formulation safe space for virtual bioequivalence of dermatolog... by J. F. Clarke (14200124)

“…The tested dosing scenarios showed decreased sensitivity for all formulation parameters with a decreased dose. …”

DataSheet1_A mechanistic physiologically based model to assess the effect of study design and modified physiology on formulation safe space for virtual bioequivalence of dermatolog... by J. F. Clarke (14200124)

“…The tested dosing scenarios showed decreased sensitivity for all formulation parameters with a decreased dose. …”

Limiting the amount of growth factors produced by fibroblasts in the no repair (NR) ABM revealed that only a large reduction in TGF-β levels altered the collagen density following... by Amanda M. Westman (10777800)

“…A 75% reduction of TGF-β secretion by fibroblasts increased the number of SSCs present and decreased the rate and amount of collagen accumulation (A). …”

Supplementary Material for: Gonadotropin-Releasing Hormone Agonists During Gonadal Chemotherapy for the Effect on Pregnancy Outcome and Ovarian Function in Premenopausal Patients W... by Yuan Y. (3237453)

“…For secondary endpoints, the GnRHa group improved menstrual recovery rates (RR=1.20; 95% CI: 1.11-1.30), and decreased the rate of amenorrhea 1-2 years after chemotherapy (RR=0.50; 95% CI: 0.40-0.63). …”

Table_2_Acute Stress and an Electrolyte- Imbalanced Diet, but Not Chronic Hypoxia, Increase Oxidative Stress and Hamper Innate Immune Status in a Rainbow Trout (Oncorhynchus mykiss... by Leonardo J. Magnoni (6627971)

“…The dietary challenge was also associated with a decrease in the alternative complement pathway activity (ACH₅₀) in plasma, suggesting an impaired innate immune status in that group. …”

Table_1_Acute Stress and an Electrolyte- Imbalanced Diet, but Not Chronic Hypoxia, Increase Oxidative Stress and Hamper Innate Immune Status in a Rainbow Trout (Oncorhynchus mykiss... by Leonardo J. Magnoni (6627971)

“…The dietary challenge was also associated with a decrease in the alternative complement pathway activity (ACH₅₀) in plasma, suggesting an impaired innate immune status in that group. …”

Table 1_Impact of co-infections and immune responses on clinical severity of human adenovirus 3 and 7 infections in hospitalized children with lower respiratory tract infections: a... by Xiaolin Ma (701778)

“…Immune cell analysis indicated that HAdV-7 infections led to a more pronounced decrease in CD3+ T cells (1596.8 vs 2444.8 cells/l, p=0.042), CD8+ cytotoxic T cells (668.6 vs 774.0 cells/µl, p=0.045), and increased NK cell percentages (11.5% vs 9.0%, p=0.044) compared to HAdV-3 infections.…”