Directed evolution of HIV-1 to utilize CD4^low target cells. by David Beauparlant (3491435)

“…<b>(E)</b> Adaptation to CD4^low target cells results in high resistance to CD4 inhibitor compared to wild type HIV-1 isolates. Comparison of IC50 of CD4-blocking DARPin 55.2 against 41 wild-type HIV-1 strains from different clades (black dots, see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006255#ppat.1006255.s003" target="_blank">S3 Table</a> for details on virus panel and individual IC50 values) and the CD4^low adaptation virus panel (colored dots, see legend) probed by Env pseudovirus infection on TZM-bl cells. …”

HCV elicits differential expression of circRNAs. by Tzu-Chun Chen (787255)

Spatial structure of precipitation anomaly trend (left column) and trend difference relating to changes in precipitation intensity distribution (right column) from ((a), (e)) GPCP,... by Chunlei Liu (57542)

“…The dry tropical oceans are marked with black dots and the dry tropical land with magenta dots (defined as the 70% lowest <em>P</em> grid points for the tropical oceans and the tropical land respectively using the 1988–2005 mean). Trends (%/decade) are calculated over 1988–2008 for GPCP and AMIP5 data sets, 1979–2005 for CMIP5 historical data and 2006–2055 for RCP 4.5 data set. …”

Topography-correlated atmospheric signal mitigation for InSAR applications in the Tibetan plateau based on global atmospheric models by Yuqing Wang (110531)

“…European Centre for Medium-Range Weather Forecasts (ECMWF) Reanalysis v5 (ERA5), ERA-Interim (ERA-I), Modern-Era Retrospective analysis for Research and Applications v2 (MERRA2) and Generic Atmospheric Correction Online Service for InSAR (GACOS), for tropospheric-phase delay reduction in InSAR applications in the Tibetan plateau, of which ERA5 is the latest GAM released by ECMWF. …”

Blockade of IFN<i>γ</i> production rescues the T_reg cell homeostatic defect and alleviates systemic autoimmunity in <i>Foxp3</i>^<i>Cre</i><i>miR-142</i><sup><... by Wei-Le Wang (133402)

Secondary attack rates among 1407 close contacts based on case-patient^a characteristics, their own characteristics, and exposure setting. by Joseph Walker (4341838)

Dendritic length of Golgi Cox-impregnated layer V pyramidal neurons in the peri-infarct cortex and in the corresponding contralateral cortex. by Katrin Frauenknecht (305672)

Efficiency of explaining and predicting risk premium in different samples. by Mihály Ormos (697939)

Cathepsin B is the main cathepsin involved in the ouabain-induced reduction in PrP^C levels. by Mohadeseh Mehrabian (455336)

Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI. by Mougina K. Eltahir (12988153)

“…(d) Scatter plots pertaining to Fig 5c show decreased inclusion of <i>MAPT</i> e2 (top), <i>CSNK1D</i> e9 (bottom left) and <i>MPRIP</i> e9 (bottom right) in DM1 hiNeurons. …”

A deficiency of TLR9 decreases chronic stress-induced changes of pro-inflammatory cytokine levels by macrophages TLR9 knockout mice or wild type BALB/c mice aged 6 to 8 weeks were... by Yanxiao Xiang (468904)

Phenotypic characterization of <i>CsIVP</i>-RNAi transgenic plants. by Shuangshuang Yan (798064)

“…<p>(A) Plant morphology of WT and <i>CsIVP-</i>RNAi lines R5, R3, and R2. …”

Mendelian randomization results with COVID-19. by Alish B. Palmos (5857379)

Schematic diagram of STTFP model. by Guozhu Sui (21672798)

Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy with Picosecond Excitation by Eric A. Pozzi (675281)

“…Phys. Chem. Lett. 2014, 5, 106−110), we demonstrate that the UHV environment decreases irreversible signal degradation. …”

Effect of obesity on contraction of mesenteric arteries to angiotensin II and norepinephrine. by Graziela N. Hagihara (623403)

Contribution of angiotensin II receptors activation to the vascular effects of angiotensin. by Graziela N. Hagihara (623403)

Effect of angiotensin II on eNOS phosphorylation in mesenteric arteries. by Graziela N. Hagihara (623403)

Altering the N-terminal arms of the polymerase manager protein UmuD modulates protein interactions by David A. Murison (3821464)

“…We find that UmuD 8 mimics full-length UmuD in many respects, whereas UmuD 18 lacks a number of functions characteristic of UmuD.…”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”