Operant self-stimulation of nigral dopamine neurons. by Mark A. Rossi (348414)

“…Self-stimulation behavior did not decrease when the animals received a second session immediately after the first. …”

Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances <i>Pseudomonas aeruginosa</i> clearance in a mouse peritoneal implant infection... by Jing Luo (146659)

“…Measurement of the cytokine levels in the peritoneal lavage fluid of mice in the baicalin treatment group revealed a decrease in IL-4, an increase in interferon γ (IFN-γ), and a reversed IFN-γ/IL-4 ratio compared with the control group, indicating that baicalin treatment activated the Th1-induced immune response to expedite bacterial load clearance. …”

MYK-461 reduces contractility in feline HCM in an exposure-dependent manner. by Joshua A. Stern (819269)

Supplementary file 1_The efficacy and safety of endoscopic surgery combined with platelet-rich plasma for lumbar disk herniation: a systematic review and meta-analysis.pdf by Guimei Guo (4127074)

“…Objective<p>Lumbar disk herniation (LDH) is a common spinal disorder with an increasing annual incidence, significantly impairing patients’ quality of life. …”

Temperature Dependent Effects of Elevated CO₂ on Shell Composition and Mechanical Properties of <i>Hydroides elegans</i>: Insights from a Multiple Stressor Experiment by Vera B. S. Chan (483328)

Data_Sheet_1_State-Dependent Entrainment of Prefrontal Cortex Local Field Potential Activity Following Patterned Stimulation of the Cerebellar Vermis.PDF by Stéfanie A. Tremblay (7554821)

“…Local field potentials were recorded in the right lateral cerebellum (Crus I/II) and bilaterally in the prefrontal cortex (frontal association area, FrA) in adult male Sprague-Dawley rats. Stimulation was delivered to the cerebellar vermis (lobule VII) using single pulses (0.2 Hz for 60 s), or repeated pulses at 1 Hz (30 s), 5 Hz (10 s), 25 Hz (2 s), and 50 Hz (1 s). …”

The enhanced radiosensitization of certain cell cultures with combination of 17AAG with inhibitors of the Hsp70 induction. by Vladimir A. Kudryavtsev (3836524)

“…The similarly enhanced radiosensitization was also found in other cell cultures (A549, HT 1080 and Myc-CaP) with 50–200 nM geldanamycin or 30–100 nM radicicol, or 50–200 nM NVP-AUY922 instead of 17AAG and with 100–200 μM KNK437, or 5–20 μM NZ28 instead of quercetin and triptolide (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173640#pone.0173640.t002" target="_blank">Table 2</a>). …”

Combined M002 and irradiation to neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…Tumor volumes were measured twice weekly and reported as fold change in tumor volume ± standard error. There was a significant decrease in tumor volume in the animals treated with combined modalities for both tumor types (<b>A</b> and <b>C</b>). …”

Table_1_Ideal Cardiovascular Health in Young Adults With Established Cardiovascular Diseases.DOCX by Jane A. Leopold (12098417)

“…Young adults with cardiovascular disease (n = 349) were older, had a lower socioeconomic status, a higher prevalence of risk factors, and lower Life's Simple 7 Health Scores (6.4 ± 1.5 vs. 7.1 ± 1.5, p < 0.01) compared to young adults without cardiovascular disease (n = 696). …”

DataSheet1_Injectable hydrogel with immobilized BMP-2 mimetic peptide for local bone regeneration.pdf by Kirstene A. Gultian (13136634)

VEGF reduces miR-30b expression in HUVECs. by Grant A. Howe (2558611)

“…<p>(A) RNA was isolated from HUVEC treated with 50ng/ml of VEGF for 24h and used to profile miRNA using Affymetrix gene expression arrays. …”

Vector genomes and GFP mRNA in heart and liver. by Bryan A. Piras (314201)

“…The shGFP group showed a 77% reduction in cardiac GFP mRNA compared to the shControl group (n=7/group, p<0.0001), and while the shGFP group showed a 39% decrease in mRNA in liver, the difference was not statistically significant (n=7/group, p=0.38).…”

Determination of the changes in contact area during osmotic stimulation of adhered primary hepatocytes. by Tabea A. Mundinger (124217)

“…The original relative contact area (i) changes considerably during hypoosmotic stimulation (ii) and does not return to its original area afterwards (iii). A rapid decrease in relative contact area can be observed after returning to normoosmotic media (iv) followed by the stabilization of the relative contact area (v). b) All areas defined as relative contact areas in the consensus of both wavelengths are represented here as black areas. …”

BMAL1 and PER1 protein and transcript levels are reduced by thyroxine treatment. by Jonathan A. Hardman (714625)

“…(b,d) PER1 protein was significantly decreased by T4 at 6, 12,18 and 24 hours. BMAL1 protein levels were also decreased significantly by T4 at time points 6,12 and 18 hours showing a tendency to decrease at 0 and 24 hours. …”

AXL overexpression dampens the response to IFNα. by Scott A. Read (788751)

“…<p>Stable transfection of Huh-7 cells with PCMV6-AXL was confirmed by western blot, using antibodies against AXL or the fusion Myc tag (A). Huh-7 cells overexpressing AXL induced a stronger but more transient phosphorylation of STAT1 (B), with increased phosphorylation at 15 and 30 minutes post-IFN (50 u/ml), but a strong decrease at 1 h (2 replicates). …”

Evaluation of MGMT inhibitors with chemosensor 1. by Andrew A. Beharry (1940068)

“…<p>Incubation of purified MGMT enzyme with the inhibitors BG and PaTrin-2 led to a concentration dependent decrease in observed final fluorescence intensity, indicative of MGMT inhibition. …”

RNA degrades with time. by Jeffrey A. Blair (3178230)

“…(C) An antibody to rRNA shows a similar decrease of immunoreactivity with time, (D) but an antibody to dsDNA remains robust even after a PMI of 46 h. …”

Filamin mutants have less synchronous wing movements than control animals. by Lucas A. B. Fisher (18865005)

“…D) A 5-millisecond recording of a <i>filamin</i>^{<i>WT-GFP</i>} control fly. …”

Therapeutic efficacy study in <i>E</i>. <i>granulosus</i> infected mice. by Julia A. Loos (737868)

“…<p>(A) Box plots showing the comparative distribution of the weight (g) of cysts recovered from untreated mice (C) and treated with albendazole (ABZ, 5 mg/kg/d), metformin (Met, 50 mg/kg/d) and the combination of both drugs (ABZ+Met) for 60 days. …”

Summary of the physiological, metabolic and hypothalamic gene expression changes in exercising Siberian hamsters with free access to a running wheel compared to sedentary Siberian... by Ines Petri (531427)