FIGURE 6 from Targeting <i>MALAT1</i> Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer by Anjali Yadav (17117308)

“…The IC₅₀ values were calculated by generating a dose–response curve using GraphPad Prism software. …”

Key for figures and hypothesis tables. by Renée Deehan (326438)

“…<p>Green and red boxes = observed increases and decreases, respectively, in RNA expression of a given gene. …”

Characterization of hADRB1 and hADRB2 after trace amine challenge. by Gunnar Kleinau (103422)

“…TYR shows no agonistic effect on hADRB1 (p<0.05) and hADRB2 (p<0.01), but acts as an allosteric antagonist on hADRB1/2, indicated by a decreased maximum of stimulation (p<0.05) with comparable EC₅₀ values. …”

Exercise reduces <i>C1qa</i>⁺ microglia/monocytes in the aged cortex. by Ileana Soto (531878)

“…(B) Quantification of IBA1⁺ cells in aging, aged sedentary (Sd), and aged runner (Rn) mice shows a decrease in microglia/monocyte density in the aged runners versus the aged sedentary mice. …”

[Ca²⁺]_i oscillations during stimulation with 12 mM glucose. by Jurij Dolenšek (276793)

“…Y axis represents the normalized fraction of the difference between maximum and plateau baseline fluorescence. <b>D</b> A pseudo-colored representation of time lags between oscillation end₅₀ in the cell in which [Ca²⁺]_i decreased first and every other cell. …”

DataSheet1_Effect of Sperm Cryopreservation on miRNA Expression and Early Embryonic Development.docx by Xiaoyu Xu (356293)

“…<p>Although sperm preservation is a common means of personal fertility preservation, its effects on embryonic development potential need further investigation. …”

DataSheet1_Identification of target groups and individuals for adherence interventions using tree-based prediction models.PDF by Johannes Wendl (11213891)

“…</p><p>Results: 1) our simple linear regression model estimated a positive adherence effect, that is an increase in total costs of 10.73 Euro per PDC-point and year for diabetes type 1, 3.92 Euro for diabetes type 2 and 1.92 Euro for hyperlipidemia (all p ≤ 0.001). 2) The model-based tree detected subgroups with negative estimated adherence effects for diabetes type 2 (-1.69 Euro, 24.4% of cohort) and hyperlipidemia (-0.11 Euro, 36.1% and -5.50 Euro, 5.3%). 3) Our model-based random forest estimated personalized adherence effects with a significant proportion (4.2%–24.1%) of negative effects (up to -8.31 Euro). …”

Low SGZ proliferation and neurogenesis in the dentate gyrus of adult <i>Prnp^0/0</i> mice correlate with high numbers of double labeled NG2-BrdU cells in the molecular la... by Ana Bribián (171285)

“…<p><b>A</b>) Left: Quantification of the number of PSA-NCAM-positive and BrdU-positive cells in dentate gyrus sections from <i>Prnp^+/+</i> and <i>Prnp^0/0</i> mice one day after BrdU-labeling. …”

Inhibition of collagen cleavage by prostaglandin E(PGE) and transforming growth factor (TGF)-β2 by Elena V Tchetina (38723)

“…<p><b>Copyright information:</b></p><p>Taken from "Prostaglandin PGEat very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and , a gene linked to chondrocyte hypertrophy"</p><p>http://arthritis-research.com/content/9/4/R75</p><p>Arthritis Research & Therapy 2007;9(4):R75-R75.…”

Adherence assays. by Amit Kumar (81180)

“…The scale ranges from 0.5 to a 10-fold decrease in adherence, as compared with control samples, n = 3/group. …”

Intraplantar acid injection produced TRPV1-mediated time-dependent behavioral hyperalgesia and spinal neuron sensitization. by He Liu (67509)

“…<p>(A) Intraplantar injection of pH 5.0 PBS (10-µl), not pH 7.4 PBS (10-µl), produced thermal (top) and mechanical (bottom) hyperalgesia. …”

DNA microarray analysis of long-term stationary phase-induced gene expression in <i>E. coli</i> grown in LB broth. by Kotakonda Arunasri (385358)

“…The X-axis represents the log2 fold change and the dark vertical lines represent cut-offs at 2.0 fold decrease and increase. …”

DNA microarray analysis of long-term stationary phase-induced gene expression in <i>E. coli</i> grown in LB broth plus glycerol. by Kotakonda Arunasri (385358)

“…The X-axis represents the log2 fold change and the dark vertical lines represent cut-offs at 2.0 fold decrease and increase. …”

Differential expression of mRNA in women vs men. by Amy C. Maher (261756)

Transient ERK1/2 dephosphorylation induces dissociation of Jarid2 and Ring1B and chromatin decompaction in NMP-L cells at the <i>PAX6</i> locus but does not reduce H3K27me3 nor eli... by Claudia I. Semprich (14204821)

“…Interprobe distance measurements in >50 nuclei in the three conditions in three individual experiments (<i>n</i> = > 150 nuclei/cell type, Mann–Whitney test/rank-sum test, *** <i>p</i> ≤ 0.001) (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000221#pbio.3000221.s024" target="_blank">S10 Data</a>), this decompaction correlated with a 2.5-fold decrease in number of base pairs per nm compared to both controls (untreated NMP-L (D3): 205 bp/nm, DMSO NMP-L (D3): 218 bp/nm and MEKi NMPL (D3): 87 bp/nm). …”

Differentially expressed module (DEM) cluster analysis. by William R. Swindell (175427)

“…The right margin lists the median fold-change (PP/PN) among genes belonging to each module, along with a p-value testing whether module genes were disproportionately increased or decreased in psoriasis lesions (FDR <0.05 in each case; GSEA).…”

Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration by Leonithas I. Volakis (155515)

“…MDA-231^MYOF-KD cells exhibited a 2-fold decrease in cell stiffness, a 2-fold increase in cell-substrate adhesion and a 1.5-fold decrease in traction force generation. …”

Mapping changes in patterning after inhibition of Notch activity. by Matthew French (13007466)

“…After using PRINGLE to create an EpiMap, the epiblasts are folded at the midline and clustered with k-means to demark comparable ROIs. …”

Table 1_The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae.xlsx by Xiaoyu Zhang (62901)

“…The importance of each factor was demonstrated using mean decrease in Gini. “Admitted with a diagnosis of respiratory infectious disease” (8.39) was identified as the most important factor in the model, followed by “Hypoalbuminemia” (7.83), then “ESBL” (7.06), “Electrolyte Imbalance” (5.81), “Age > 62 years” (5.24), “The number of Positive Sputum Cultures for KP > 2” (4.77), and being bedridden (4.24). …”

Exocytosis of ATP from astrocytes <i>in situ</i> can be triggered by synaptic stimulation. by Ulyana Lalo (506296)

“…Spontaneous currents recorded in the pyramidal neurons at a holding potential of −80 mV in the presence of picrotoxin (100 µM) and CNQX (50 µM) were mediated by P2X receptors, as verified by inhibition with selective P2X antagonist NF279 (3 µM). …”