Experimental setup to measure QS activity. by Kalinga Pavan T. Silva (4523842)

“…With the introduction of signal from strain D, the fold change in LacZ decreased resulting in no activation of QS. …”

Kinetics of aggregation study of CC, HR, CD and PrP_106–126 peptides through TEM and ThT fluorescence curves. by Silvia Vilches (442014)

“…The HR peptide contains higher amounts of amyloid fibrils (A, E, I) than CC at all points (B, F, J). Note the progressive decrease in number of spherical structures over time in the CD peptide (C, G, K) and the coexistence of spherical and protofibrillar structures in the PrP_106–126 peptide samples (D, H, L). …”

Notch1 deficiency reduces the CTGF-induced collagen gel stiffness in SMCs. by Jaspreet Sachdeva (4057231)

“…VSMCs cultured in a 6-well plate and treated with or without CTGF (10 ng/ml) for 72 hours and resuspended in a collagen solution at a concentration of 6 x 10⁵ cells/ml for 48 hours. …”

Table1.doc by Bruna S. de Alencar Silva (5002919)

“…Regarding the chronic effects, it was observed a decrease of all cytokines, except IL-10 (p < 0.05). …”

Data_Sheet_1_Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells.PDF by Enrique Jiménez-Madrona (16836648)

“…Analysis of the effect of boldine (25–600 μM) on different types of primary human GBM cells (GBM59, GBM96, and U87-MG) showed a concentration-dependent decrease in GBM cell growth. …”

Image1.TIF by Bruna S. de Alencar Silva (5002919)

“…Regarding the chronic effects, it was observed a decrease of all cytokines, except IL-10 (p < 0.05). …”

NF-κB and AP-1 are involved in the induction of the antiviral state in THP-1 cells. by Natacha Merindol (3521828)

“…Numbers represent the fold decrease in % GFP⁺ cells relative to mock-infected cells treated similarly. …”

TF-specific motif turnover drives TF binding divergence. by Mathilde Paris (17385)

Expression of GlyT2 following CNX knockdown/overexpression. by Esther Arribas-González (409128)

“…<p>(A) COS7 cells were co-transfected with 0.5 µg of GlyT2 cDNA in pCDNA3 and the indicated amount of control (HPRT) or CNX siRNA. …”

MEKi inhibits growth and ablates MAPK regardless of <i>PIK3CA</i>^<i>mut</i> status. by Robert S. McNeill (5485064)

“…<p>Selumetinib IC₅₀ were similar regardless of <i>PIK3CA</i>^<i>mut</i> status in NHA (<b>A</b>), but slightly higher in most <i>PIK3CA</i>^<i>mut</i> NHA^RAS compared to parental cells (*, P≤0.03) (<b>B</b>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0200014#pone.0200014.s011" target="_blank">S11 Fig</a></b>). …”

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease by Nisha Jain Garg (102122)

“…We found 213 and 199 protein spots (fold change: |≥ 1.5|, p< 0.05) were differentially abundant in C/A and C/S individuals, respectively, with respect to N/H controls. …”

Predicted mutation selection windows for <i>E</i>. <i>coli</i> exposed to ciprofloxacin. by Fabrizio Clarelli (3622889)

“…The blue line represents the wild-type strain based on the fits shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008106#pcbi.1008106.g003" target="_blank">Fig 3</a>, and the red line represents a strain with a hypothetical resistance mutation that decreases the binding rate (<i>k</i>_<i>f</i>) 100-fold and imparts a 15% fitness cost. …”

Data Sheet 1_HIV latency potential may be influenced by intra-subtype genetic differences in the viral long-terminal repeat.pdf by Deelan Sudhir Doolabh (18872095)

“…The median latent:active infection ratio decreased by a median of 3-fold following PMA/Ionomycin stimulation to 0.55 (range 0.46–0.78) indicating that a proportion of latently infected cells could produce viral proteins upon activation. …”

Proteomic and phosphoproteomic time course over cell–cell fusion. by Melvin Bérard (7907558)

“…(<b>D</b>) Fold enrichment for TORC, TORC1, TORC2, Orb6, and Cdc2 substrates among phosphosites that change (gray), decrease (blue) or increase (red) in abundance during cell–cell fusion. …”

Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice by Miroslava Anderova (155561)

“…Similarly, evaluation of relative α changes showed a significantly smaller decrease in α-syntrophin knockout mice only during severe pathological conditions, but not during mild stimuli. …”

Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx by Akihiro Kambara (10006775)

“…The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”

Table1_Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients.XLSX by Gaurav Tripathi (3163251)

“…Post therapy, 62 plasma metabolites (12 upregulated and 50 downregulated, FC±1.5, p < 0.05) differentiated nonresponders from responders and highlighted a significant increase in the steroid and histidine metabolism and significant decrease in tryptophan metabolism and ascorbate and pyruvate metabolism in the nonresponders. …”

Partial silencing of GFP requires both EhRNaseIII and ScaAgo1. by Justine M. Pompey (268775)

“…FACS histogram of GFP fluorescence in the indicated strains show a decrease in GFP fluorescence in strain expressing EhRNaseIII using the strong GFP silencing hairpin but only in the strain expressing ScaAgo1. …”

datasheet1_In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis.docx by Dahara Keyse Carvalho Silva (9774635)

“…In vitro incubation with LASSBio-1386 reduced the percentage of Leishmania-infected macrophages and the number of intracellular parasites (EC₅₀ = 9.42 ± 0.64 µM). Also, in vivo treatment of BALB/c mice infected with L. amazonensis resulted in a decrease of lesion size, parasitic load and caused histopathological alterations, when compared to vehicle-treated control. …”

MK-2206 induced cytotoxicity, inhibited proliferation and was able to overcome the protective effects of the tumor microenvironment. by Vijay Ramakrishnan (117159)

“…<p>When we cultured MM cell lines with indicated concentrations of MK-2206 for 48 hrs we observed dose dependent decrease in <b>A)</b> viability as observed by MTT assays and <b>B)</b> tritiated thymidine uptake indicative of inhibition of proliferation albeit with differences in the sensitivity of cell lines to MK-2206. …”