The bifunctional pT2K-CAG-EGFP-183F plasmid expresses functional members of the miR-183 family <i>in vitro</i>. by Kaidi D. Zhang (770061)

“…When pGFP-183F was included in the transfection, the appropriate miRNA reporter showed a significant decrease in luminescence compared to control wells (DF-1 cells co-transfected with pGFP and the appropriate miRNA reporter). …”

Direct effects of duration. by Martin Wiener (249995)

“…(<b>b</b>) Average chronometric functions for auditory and visual participants. Reaction time decreased as a function of duration, but dropped off faster after the BP was passed and was faster for auditory stimuli at the longest duration tested. …”

Fsn0503 inhibits angiogenesis <i>in vivo</i>; CD34 Immunohistochemical analysis of Fsn0503 treated tumors. by Claire Ward (362061)

“…(<b>C</b>) A significant reduction is observed in the mean vessel area of tumours treated with Fsn0503 (p<0.001).…”

Role of Dendritic Release in Generating Bursts. by Enrico Rossoni (271791)

“…<p>(A) Upper trace: The evolution of the mean firing rate in the model (in spikes/s; average over all neurons); the vertical axis has been capped to highlight the fluctuations of the basal activity. …”

Table_1_Correlation of HBV DNA and Hepatitis B Surface Antigen Levels With Tumor Response, Liver Function and Immunological Indicators in Liver Cancer Patients With HBV Infection U... by Shida Pan (12696593)

Erk and PI3K signal patterns determine Myc temporal behaviors. by Tae Lee (42532)

Wnt/β-catenin signaling down-regulation is both dependent and independent of HIF expression. by Donald J. Scholten II (649432)

“…<p>A, Levels of active β-catenin were determined by western blot at different hypoxia time points for each of the shRNA in MNNG/HOS cells. …”

Notch induces phenotypic changes in the hepatocytic cell line AML-12. by Carola M. Morell (4594864)

“…The increased expression of Notch target genes Hes1, Hey1 and Hey2 in Jag1 treated cells confirmed that this was a Notch-dependent process. No significant changes in gene expression were detected in the cells treated with Shh at any time point. …”

Inhibition of infection in cells depleted of β6 and β8 integrins. by Biljana Petrovic (3935240)

“…<p>(A) Extent of integrins silencing. SK-OV-3 cells were doubly silenced for β6 and β8 integrins (siRNA β6+β8), or mock-silenced (siRNA ctrl). …”

The senescence-dependent spatial reorganization of H3K9me3-marked chromatin differs at the perinucleolar space and the nuclear periphery. by Stefan Dillinger (4063552)

“…<p>(<b>A</b>) Semi-quantitative immunoblots show severely decreased H3K9me3 and Lamin B1 levels, less strongly decreased H3 levels and no detectable alterations in Lamin A/C, tubulin and GAPDH levels in senescence. …”

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice by Asimina Hiona (246175)

“…At the biochemical level, sarcopenia in D257A mice is associated with a marked reduction (35–50%) in the content of electron transport chain (ETC) complexes I, III and IV, all of which are partly encoded by mtDNA. …”

Antidromic stimulation of the ventral roots to identify the location of the motor nucleus. by Yoshiyasu Arai (378937)

“…Each optical signal is the response to a single antidromic stimulus averaged from a train of stimuli (8 stimuli at 20 Hz) and recorded in the presence of a cholinergic (mecamylamine 50 µM) and a GABAA (bicuculline 50 µM) antagonist to block the synaptic inputs from R-interneurons onto motoneurons (33). …”

Molecular mechanism of the inhibitory activity of VEZT on gastric cancer growth. by Ruizhen Miao (459710)

“…<p>(A) TCF19-transfected MKN-45 showed increased percentage of G2/M phase cells and decreased percentage of S and G0/ G1 phase cells. …”

Early cytokines determine pathogenesis of HIV/SIV infection. by Peter D. Katsikis (346398)

“…(B) Cytokines either increase (↑) or decrease (↓) immune parameters or target availability and therefore directly influence viral replication and viral set-point (effects of cytokines are adapted from <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002055#ppat.1002055-Ansari1" target="_blank">[8]</a>, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002055#ppat.1002055-Mueller1" target="_blank">[10]</a>, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002055#ppat.1002055-Naicker1" target="_blank">[23]</a>, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002055#ppat.1002055-Shin1" target="_blank">[66]</a>, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002055#ppat.1002055-Wang1" target="_blank">[70]</a>). …”

Tyramine-mediated reduction in GABA synaptic release requires SER-2. by Jamie L. Donnelly (397302)

“…SER-2 was expressed in <i>ser-2(pk1357)</i> mutant animals. Each data point represents the mean percentage of animals immobilized by aldicarb scored every 30 min ± SEM for at least four trials, totaling a minimum of 60 animals. …”

Table_1_Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation.docx by Qinsheng Lu (778233)

“…Taken all together, the immunohistochemical data suggest a decrease in bioavailability, receptor binding capacity, and signaling in the endometrium of women with HMB compared with controls. …”

Bioenergetic analysis of Opa1 morphants. by Jennifer J. Rahn (343062)

“…<p>Oxygen consumption rates (OCR) were measured in 24, 48, and 72 hpf morphants (mean +/− SEM, n = 5–10). <b>A.</b> Opa1 morphant basal respiration was significantly decreased compared to MMC morphants at 24 and 72 hpf (p = 0.004 (a) and p = 0.0007 (b), respectively). …”

Kinetic characterizations of AChR blockade by PQ1–5. by Wan-Chen Lin (658261)

“…Currents are displayed as upward deflections. (B) Dose-dependent decrease in the apparent mean open time (τ_app) of the AChR. …”

National Land Cover Database (NLCD) Tree Canopy Cover (TCC) Puerto Rico USVI by U.S. Forest Service (17476914)

“…Data for this record includes the following resources:</div><ul><li> <a href="https://www.arcgis.com/sharing/rest/content/items/50ad050c2cd44598a9bee2b4990de85e/info/metadata/metadata.xml?…”

Changes of plasma membrane potential of live HAECs treated with or without 10 µg/ml DEPs assayed by flow cytometry. by Yangzhe Wu (162008)

“…<p>(a) Representative graphs show that DEP exposure induced a significant decrease in fluorescence intensity of DiBAC4(3). …”