Presentation_1_Schedule-Dependent Synergy Between the Histone Deacetylase Inhibitor Belinostat and the Dihydrofolate Reductase Inhibitor Pralatrexate in T-and B-cell Lymphoma Cells... by Godefridus J. Peters (121184)

“…Exposure to IC25 of PLX did not decrease the IC50 for BLS (CI from 0.6–1.2), but exposure to IC25 of BLS markedly increased PLX sensitivity (low CIs from 0.40 to 0.66). …”

Changes in genetic diversity and the McDonald-Kreitman related index (MKR) for varying strengths of strain competition and antigenic mutation rates. by Daniel Zinder (106377)

“…<p><b>(A)</b> Mean pairwise genetic diversity π is measured as the mean distance, measured in years, for the coalescence of random pairs of contemporaneous samples in a tree. …”

Excitability of motor cortex is not affected by cTBS over somatosensory (“som”) cortex, whereas cTBS over motor cortex suppresses its excitability. by Neeraj Kumar (109718)

“…<p>cTBS to somatosensory cortex decreases perceptual acuity. (A) Mean time series of MEPs recorded from biceps brachii pre- (blue) and post-cTBS (red) from a representative participant. …”

Expression of grapevine expansins in the V. vinifera cv Corvina atlas. by Silvia Dal Santo (268493)

“…The color scheme used to represent expression level is red/green: black boxes indicate a low variation in expression, green boxes indicate a fold decrease and red boxes indicate a fold increase with respect to the mean value. …”

Supplementary Figure S1 from Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain M... by James S. Wilmott (15008931)

“…<p>Gene expression of major signalling pathways and multiplex immunohistochemical comparison of markers between timepoints and tumor sites. A) Gene expression of related oncogenic signalling pathways between treatment timepoints and site, B) Estimated mean difference of proteins and pathways between biopsy categories (95% confidence interval for the estimated mean difference is depicted as a segment), C) Multiplex immunohistochemical staining for key intracellular signalling proteins, D) Changes in immune intratumoral immune cell densities between treatment timepoints and site, E and F) Multiplex immunohistochemical staining depicted marked decrease in immune cell densities EDT in PT4 (steroid treated). …”

Time courses of choice probabilities after sequence onset in three regions of the auditory forebrain. by Elena Selezneva (4537447)

“…<p>(A) The thick lines show mean CPs of 239 multiunits recorded in RAC. …”

Network Analysis. by Vladimir Tolstikov (133808)

“…Dotted lines represent indirect relationships between nodes. Red colored lines point to activation and blue to inhibition. Yellow lines indicate an inconsistent state of a downstream molecule. …”

Effects of HFD on glucose regulation and hyperlipidemia in NOX2-FL and mNOX2-KO mice. by Jennifer K. Pepping (4330654)

“…<p><b>(A)</b> Fasting blood glucose levels. Data are mean and SEM, and ** indicates significant (p < 0.01) increase in fasting blood glucose level in HFD-fed NOX2-FL mice as compared to CD-fed NOX2-FL mice, while # depicts significant decrease in fasting glucose in HFD-fed mNOX2-KO mice as compared to HFD-fed NOX2-FL mice. …”

Forward scores follow exponential tails with constant <i>λ</i>. by Sean R. Eddy (5840)

“…Variation in is represented by plotting quartiles (black bars) and most extreme outliers (grey triangles) in addition to the means. approaches the conjectured log 2 as fitted tail mass decreases, but beyond a certain point, variance increases. …”

Live Fast, Die Young: Experimental Evidence of Population Extinction Risk due to Climate Change by Elvire Bestion (818248)

Metabolic dysfunction of cardiomyocytes is dependent on the presence of rVλ6Wil fibrils. by Helen P. McWilliams-Koeppen (116503)

“…<p>(A) Supernatants from a suspension of rVλ6Wil fibrils generated by centrifugation of a fibril suspension at either 435,000 x g or 16,000 x g do not decrease MTT reduction by cardiomyocytes (supernatants were used at a 1x or 10x volume equivalent [vol. eq] to the unfractionated fibril suspension). …”

PAR1 or PAR4 activation reduces urothelial MIF in mouse bladder. by Dimitrios E. Kouzoukas (746678)

“…White arrows point to intraluminal surface of the urothelia. MIF immunofluorescent labeling localized to urothelium (<b>A, D</b>) and a decrease in urothelial MIF immunofluorescence was observed after PAR1-AP (<b>B</b>) or PAR-4-AP (<b>E</b>) treatment when compared to control peptide-treated groups (<b>A</b>, <b>D</b>). …”

Quantitative proteomics analysis indicates metabolic changes due to executioner caspase deficiency in accordance with reduced myocyte maturation. by Maria Cardona (227256)

“…<p><b>(A-D)</b> Relative abundance profiles of selected proteins along development (0, 1, 3 and 8-month-old) in both wild type (WT) and caspase-3 and -7 knockout (KO) animals; in the left and middle columns, the changes are expressed separately for KO and WT animals in relation to the abundances at t = 0, while in the rightmost column the abundance of proteins in the KO are compared with that of the WT animals at each time point. …”

Inhibition of myosin IIB activity increases the number and length of filopodia-like protrusions. by Jennifer L. Hodges (207936)

“…Arrows point to different spine morphology types. <b>B</b>) Hippocampal neurons were co-transfected at DIV 6 with GFP and either an shRNA vector against MIIB (pSUPER-IIB) or a control empty vector (pSUPER). …”

Shared Investment Projects and Forecasting Errors: Setting Framework Conditions for Coordination and Sequencing Data Quality Activities by Stephan Leitner (710454)

“…Furthermore, we show that—in some setups—a certain extent of misforecasting is desirable from the firm’s point of view as it supports the achievement of the corporate objective of value maximization. …”

Data_Sheet_1_Inside the Alterations of Circulating Metabolome in Antarctica: The Adaptation to Chronic Hypoxia.PDF by Michele Dei Cas (12217586)

“…The non-polar metabolome revealed a modest decrease in the concentration of all the major lipid classes. …”

Effect of laser therapy on the inflammatory response induced by endodontic medications implanted into the subcutaneous tissue of rats by Felipe de Souza MATOS (6125111)

“…Analysis of variance (ANOVA) and Tukey's post-hoc test were applied to determine significant differences in the number of mast cells between groups (p<0.05).RESULT: There was a decrease in mast cells for the HL, HPL and IL groups when compared with the HS, HPS and IS groups at both time points. …”

Data_Sheet_1_Inside the Alterations of Circulating Metabolome in Antarctica: The Adaptation to Chronic Hypoxia.PDF by Michele Dei Cas (6475358)

“…The non-polar metabolome revealed a modest decrease in the concentration of all the major lipid classes. …”

Supplementary Material for: Urine Metabolomics by ¹H-NMR Spectroscopy Indicates Associations between Serum 3,5-T₂ Concentrations and Intermediary Metabolism i... by Pietzner M. (4152400)

“…In detail, the odds for intermediate or suppressed serum 3,5-T₂ concentrations doubled owing to a 1-standard deviation (SD) decrease in urine trigonelline levels, or increased by 29-50% in relation to a 1-SD decrease in urine pyroglutamate, acetone and hippurate levels. …”

Table1_Peak appearance time in pulse waveforms of intracranial pressure and cerebral blood flow velocity.DOCX by Arkadiusz Ziółkowski (14325084)

“…Further study is needed to test whether PAT of the CBFV pulse may serve as an indicator of changes in ICP–this may open a perspective for non-invasive monitoring of alterations in mean ICP.…”