IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

Increase in resistance grade is correlated with the loss of <i>in vitro</i> parasite infectivity and decreased cutaneous lesion size. by Jairo E. Perez-Franco (3166050)

DHA decreased cell viability in HepG3 cells. by Arlet Hernandez (12289155)

Gene clustering identifies up- and down-regulated groups that control development, pluripotency, and cell division. by Michael Shelton (382572)

“…<p>Pluripotent H9 hESCs were differentiated for 50 days as previously described [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0222946#pone.0222946.ref012" target="_blank">12</a>], beginning with high (7.5 μM or 10 μM) CHIR99021 concentrations. mRNA samples from the indicated time points were subjected to gene expression profiling. …”

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

Subjects:

The <i>Becn1</i> F121A mutation inhibits the BECN1-BCL2 interaction in vivo. by Altea Rocchi (3278457)

Subjects:

Autophagosomal sequestration of Aβ42 in brain of autophagy-hyperactive mice. by Altea Rocchi (3278457)

Subjects:

An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

Subjects:

A <i>Becn1</i> mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease by Altea Rocchi (3278457)

Subjects:

<i>Becn1</i>^F121A improves the survival rate of PDAPP AD mice. by Altea Rocchi (3278457)

Subjects:

(a) the wild type with SHV in the left panel and its neighbors in the wild type are shown (b) the S130G mutant in the right panel and its neighbors in the mutant type its neighbors... by Mohd Hassan Baig (441304)

Inhibition and assessment of the biophysical gating properties of GluA2 and GluA2/A3 AMPA receptors using curcumin derivatives by Mohammad Qneibi (7314050)

“…Thus, the current study investigated novel curcumin derivatives on the biophysical properties of AMPA receptors, specifically on the homomeric GluA2 and the heteromeric GluA2/A3 subunits and assessed for inhibitory actions. …”

Overexpression of U1 snRNA induces decrease of U1 spliceosome function associated with Alzheimer’s disease by Zhi Cheng (729515)

“…These findings not only helped researchers better understand the functions of U1 snRNA, but also paved the way to reveal the mechanisms of AD from a different point of view and may find a new therapeutic target for the disease.…”

Decreased numbers of motor neurons in Tc1 and Dp(16)1Yey mice. by Sheona Watson-Scales (586942)

Mice carrying 100P mutations show region-specific decreases in proportions of PV-expressing cells. by Malgorzata Borkowska (3166719)

Space impression evaluated using the SDM (7-point Likert scale). by Hiroyuki Fukumoto (18197728)

The second-order rate-yield tradeoff demonstrated by decreasing the P/O ratio and and knocking out <i>gnd</i> (“Δ<i>gnd</i>”) in ME-model simulations. by Chuankai Cheng (6791417)

BrdU incorporation is elevated in clrn1-/- zebrafish at 4 mpf and decreases with age. by Hannah J. T. Nonarath (20861735)

“…Quantification of Brdu+ nuclei in the (e) outer nuclear layer (ONL, or Photoreceptor layer) and (f) inner nuclear layer (INL) revealed an increase in BrdU incorporation for <i>clrn1</i>^<i>-/-</i> zebrafish at the youngest time point which decreased with age. White arrows highlight BrdU+ nuclei. …”

Ni causes a decrease in membrane sterols in A549 lung epithelial cells. by Amber R. Matha (19681603)