Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2 by Mrigank Srivastava (94935)

“…Nized and BAL cells (A, B), freshly isolated type II alveolar epithelial cells (A, C), lung homogenate (A, D), and concentrated BAL fluid supernatant (E) were prepared for analysis of cath K mRNA by real-time RT-PCR (A) and western blotting (B-E). …”

Silencing of CAV1 inhibited the migration and invasion of SNU-449 cells and decreased the formation of complex branching tubular structures. by Peyda Korhan (620109)

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)

Not1 reduction decreases 4E-BP mRNA through the promoter region of 4E-BP gene. by Hirokazu Okada (323221)

In the absence of <i>eIF4E1</i>, global translation activity decreases while virus accumulation increases. by Delyan Zafirov (17420106)

RV infection decreases IRAK-1 protein levels in both BEAS-2B and primary airway epithelial cells. by Benjamin L. Unger (130418)

Inhibition of GLS1 decreases the proportion of CCR6 and CXCR3 expressing CD4⁺ T cells. by Zeynep Sener (3146064)

“…Data points in panels B-E represent results from three different donors (n = 3, Mean ± SD, ****p˂0.001, ***p˂0.005, **p˂0.01)</p>…”

Chemical inhibition of formins decreases actin pedestal assembly by EPEC, but not by KC12+EspF_U. by Katrina B. Velle (4330957)

U87MG glioma cells transduced with gal-3 shRNA demonstrate decreased tumor size and growth. by Rafael Yamashita Ikemori (698128)

“…The delay presented for the decrease in tumor size and growth in the gal-3 shRNA cells was not due to a decreased tumor cell proliferation <i>in vitro</i> when compared to scramble shRNA cells. …”

Female EIIIA-cFN null mice have decreased accumulation of intracellular lipids at day 2 after PHx. by Bridget Sackey-Aboagye (3221319)

“…Oil Red O staining was decreased in female EIIIA-cFN null mice <b>(B)</b> in comparison to wild type littermates <b>(A)</b>. …”

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Absence of neocortex is associated with a dorsal shift of piriform cortex in <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
Get full text
Get full text
Get full text

Decreased clonogenic capacity of U87MG and U251MG glioma cells dependent on SHG-44 concentration. by Denis Mustafov (19137870)

“…<b>(B)</b> A significant decrease in the proliferative clonal capacity of U251MG colonies was observed with 50ΜM and 100ΜM SHG-44 treatment. …”

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…<i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
Get full text
Get full text
Get full text

Differential protective effects of a history of thyroid cancer on breast cancer-specific mortality in patients at age<50years and age≥50years at the diagnosis of breast cancer. by Weiwei Cheng (582223)

IFNAR1 is decreased on CD103⁺ DCs in the PPs of mice following treatment with La-IFN-β. by Adelle P. McFarland (229619)

Capsaicin, pyridoxine, vincristine sulfate and ionomycin significantly decreased axon length ratio but only pyridoxine had no impact on neurotoxicity. by Fei San Lee (17282886)

“…At a lower dose, 50 μM Pyr, did not induce significant change in axon length ratio over time and between PBS control in both female and male rat DRGs. …”