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point decrease » point increase (Expand Search)
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22161
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”
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22162
Image_4_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici...
Published 2020“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”
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22163
The Effect of Ligand Lipophilicity on the Nanoparticle Encapsulation of Pt(IV) Prodrugs
Published 2013“…As the platinum concentration was increased, there was an initial increase in encapsulation followed by a decrease due to macroscopic precipitation. Maximal loading occurred when the platinum complex was present at a 40% w/w ratio with respect to polymer during the nanoprecipitation step. …”
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22164
Genetic evaluation of growth in Polled Nellore via multi-trait models
Published 2018“…Unlikely, a decrease was observed from W205 to W365 for the maternal permanent environmental effect. …”
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22165
Image_2_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici...
Published 2020“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”
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22166
Mitochondrial Ca<sup>2+</sup> uptake in permeabilized H295R cells transfected with <i>OPA1</i> or <i>Mfn1</i> siRNA.
Published 2011“…On day 5 the cells were permeabilized, superfused with a cytosol-like medium, Ψ<sub>m</sub> was dissipated with 10 µM rotenon, 8 µg/ml oligomycin, 10 µM FCCP and 50 ng/ml valinomycin for 2 minutes. …”
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22167
3BrP effect on glycolytic enzymes as well as on differentiation markers assessed via embryoid body (EB) formation.
Published 2015“…<p>ESCs were maintained in control conditions (with LIF), in the absence of LIF (differentiation control) and in the presence of two different 3BrP concentrations (25 and 50 μM) plus LIF. <b>A)</b>- Left: Protein levels for Hexokinases II and I, Gapdh and PDH were determined by Western Blot and quantified by densiometric evaluation. …”
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22168
Actively station: Effects on global cognition of mature adults and healthy elderly program using eletronic games
Published 2018“…Results: The cognitive performance of the TG improved significantly after the program, particularly in the domains of language and memory, and there was a decrease on the anxiety index and frequency of memory complaints, when compared to the CG. …”
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22169
Table_2_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici...
Published 2020“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”
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22170
AP-1 knockdown potentiates the effect of AP-3 knockdown on regulated secretion.
Published 2013“…<p>(A) PC12 cells were transfected with pooled siRNA directed against AP-1 γ or pooled nontargeting siRNA as control. …”
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22171
Image_3_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici...
Published 2020“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”
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22172
Discovery of Novel Celastrol Derivatives as Hsp90–Cdc37 Interaction Disruptors with Antitumor Activity
Published 2019“…Among all the target compounds, <b>41</b> was screened with superior antiproliferative activity on related cancer cells (IC<sub>50</sub>: 0.41–0.94 μM) and <b>41</b> could decrease the level of the Hsp90–Cdc37 complex in A549 cells. …”
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22173
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”
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22174
Dental pain prevalence among health care personnel
Published 2021“…<div><p>ABSTRACT BACKGROUND AND OBJECTIVES: Dental pain is a major reason for looking for dental services. …”
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22175
MMR activities in the APE and hMSH6 expressing cells
Published 2011“…The repair efficiency was calculated as the percentage of decrease in the mixed-color colonies. The values are a mean ± SD from three separate experiments. …”
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22176
Effects of variation in pDC number and activation status.
Published 2010“…<p>(A) Virus kinetics in spleen following infection with low (5×10<sup>1</sup> pfu), intermediate (5×10<sup>3</sup> pfu) and high (5×10<sup>5</sup> pfu) dose infections under conditions of varying pDC numbers per spleen. …”
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22177
Datasheet1_Trends in hypertension and hypertension treatment in primary care in general practices in Germany between 2013 and 2022.pdf
Published 2024“…After adjusting for covariates, there was a significant decrease in the number of patients diagnosed with hypertension (beta coefficient = −7.91, p-value < 0.001) and treated with any antihypertensive drug per practice per year between 2013 and 2022 (beta coefficient = −5.40, p-value < 0.001).…”
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22178
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”
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22179
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates
Published 2021“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”
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22180
Supplementary Material for: Effects of Simvastatin on inflammatory response and biological behavior of adamantinomatous craniopharyngioma
Published 2024“…Western blot analysis demonstrated SIM inhibited nuclear factor-kappa B (NF-κB) p65 activation expression while promoted the expressions of Cl-caspase-3 and P38 MAPK. CCK8 assay indicated a decrease in ACP cell activity upon SIM treatment. …”