Defects in skin lipid composition and cellular lipid efflux mediated by Abca12. by Ian Smyth (54249)

“…Expression of Abca1 was determined at the protein level by Western blotting (C, upper panel) and decreases in <i>Abca12</i> homozygous mutant cells were shown to be in part due to decreases in transcription of <i>Abca1</i> (C, lower panel, fold change in transcription relative to el12/el12, ***p<0.0005). …”

Table4_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table6_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table1_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table2_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table3_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table5_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table6_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Table1_Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions.xlsx by Li Peng (83452)

“…Moreover, PF decreased the serum levels of IgE, LTB4, and HIS, and PF administration at ZT10 produced relatively superior effectiveness. …”

Data_Sheet_1_Clinicians' preferences for managing aneurysmal subarachnoid hemorrhage using endothelin receptor antagonists.pdf by Sebastian Heidenreich (12523516)

“…</p>Methods<p>An online choice experiment was conducted to elicit preferences of neurologists, intensivists, and neurosurgeons treating aSAH in the US and UK for the use of ERAs. The design of the choice experiment was informed by a feasibility assessment (N = 100), one-on-one interviews with clinicians (N = 10), a qualitative pilot (N = 13), and a quantitative pilot (N = 50). …”

Monitoring of IFN-γ and IL-2 production in subjects with chronic Chagas disease and treated with benznidazole. by María G. Alvarez (166567)

“…<p>IFN-γ– or IL-2-producing T cells were measured at different time points after benznidazole treatment or enrollment (for untreated subjects). …”

Myelomonocytic expansion in blood, bone marrow, and spleen of young TAK1^ΔM mice. by Betty Lamothe (57187)

“…(<b>C</b>) Bone marrow biopsy specimens and bone marrow smears (<i>left panels</i>) from 7-week-old TAK1^F/+ and TAK1^ΔM mice were stained with H&E and Wright-Giemsa, respectively. Note the increase in blasts with large folded nuclei and basophilic cytoplasm (<i>arrows</i>) in TAK1^ΔM mice. …”

Quantification of PLN sinus volume capacity (SVcap) using CE-US. by Echoe M. Bouta (456220)

“…To normalize the SV to changes in FPsi following injection, the SVcap was calculated as (SV*SVsi)/FPsi. Note the 2-fold increase in SVcap at all time points following contrast injection.…”

Table_7_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX by Shenqiang Hu (3687574)

“…Ovaries of 6 does at different time points during gonadotrophic stimulation were collected for histomorphological examination and genome-wide analysis of miRNA and mRNA transcriptomes, and the plasma were separated for detecting melatonin (MT), prostaglandin E₂ (PGE₂), estradiol (E₂), and progesterone (P₄) levels. …”

Table_6_Integrated Analysis of mRNA and miRNA Expression Profiles in the Ovary of Oryctolagus cuniculus in Response to Gonadotrophic Stimulation.DOCX by Shenqiang Hu (3687574)

“…Ovaries of 6 does at different time points during gonadotrophic stimulation were collected for histomorphological examination and genome-wide analysis of miRNA and mRNA transcriptomes, and the plasma were separated for detecting melatonin (MT), prostaglandin E₂ (PGE₂), estradiol (E₂), and progesterone (P₄) levels. …”

Comparison of qualitative experimental input–output relations and model predictions. by Linda Irons (9292686)

“…Default uniform model parameters are <i>n</i> = 1.25, <i>EC</i>₅₀ = 0.55, <i>b</i> = 0.2 and <i>p</i> = 0.3 (Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008161#pcbi.1008161.e001" target="_blank">1</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008161#pcbi.1008161.e004" target="_blank">4</a>), with weights <i>w</i> = 1 (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008161#sec008" target="_blank">Methods</a>). …”

Ca²⁺-induced inhibition of ferrocytochrome <i>c</i> oxidase activity in mitochondria. by Tatiana Vygodina (456671)

“…<p>(<b>A</b>) Rat liver (1.3 mg protein/ml) or rat heart mitochondria (0.6 mg protein/ml) in the medium containing 0.25 M sucrose, 50 mM HEPES/tris pH 8.0, 0.4 M choline chloride, 100 µM EGTA, and also 1 µM cyclosporine A and 1 µM the uncoupler, CCCP. 15 µM of the reduced cytochrome <i>c</i> is added and its oxidation is followed at 550 nm vs the 535 nm reference. …”

Increased carrying capacity reduces the benefit of adaptive therapy by reducing spatial competition. by Masud M A (12219010)

“…The spatial carrying capacity was characterized as <i>K</i> = 1 (each lattice point could hold one cell) or <i>K</i> = 2 (each lattice point could hold, at most, two cells, regardless of their sensitivity or resistance). …”

RNA for the antifolate target dihydrofolate reductase-thymidylate synthase is not overexpressed in WR99210-treated cells. by Karthikeyan Ganesan (269200)

“…Two, the exact scheme was repeated with independently grown parasites, thus generating 4 hybridizations per time point of WR99210 treatment. This scheme was labeled <i>SD</i>, <i>for Sensitive</i> cells treated with the <i>drug</i> analog WR99210. …”

Differentially expressed genes in selected immune cell types during <i>L</i>. <i>major</i> infection. by Gopinath Venugopal (638444)

“…<p>Volcano plot showing the DEGs in macrophages (A), resident macrophages (B), inflammatory monocyte (C), neutrophils (D), BECs (E), and LECs (F). Colored dots indicate genes at least 2 (natural log ~0.693) fold increased (red) or decreased (blue) in infected cells relative to naive cells with an adjusted p-value < 0.05.…”