Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

CD14 controls LTA and Pam₃CSK₄ internalization and NF-κB activation. by Karim J. Brandt (362950)

“…CD14 blocking antibody decreases significantly TNF production. Data are represented as mean +/- SD of at least 4 independent experiments. …”

Table 1_Single-case report: dynamic changes in cardiac function during shamanic journeying and Qigong meditation.docx by Emma R. Huels (10321976)

“…The LF/HF ratio decreased further in the second post-shapeshift period, while HF power and pNN50 were increased compared to drumming initiation. …”

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Response to NLC for 1 122 native plant species with significant null models. by Kaixuan Pan (11714457)

“…<p>3 species with a neutral (without a relationship, named ‘None’) response were omitted as not preferring any NLC. a-h, Response curves of plant species to NLC. i-l, Summary statistics of preferred NLCs. a, Summary of all 1 122 native plants responding to NLC (with percentages in parentheses). b-d, Response curves of species with decreasing (each magenta line indicates one species) (b), unimodal (each blue line indicates one species) (c) and increasing (each green line indicates one species) (d) relations with NLC. …”

Summary sketch of a L2/3 SNHL pyramidal neuron by Vibhakar C. Kotak (53276)

“…The cumulative outcome of such robust homeostatic alterations following hearing loss may adjust the cortical network at a new set point in anticipation that peripheral activity will be restored.…”

<i>Smed-not1(RNAi)</i> animals maintain mitotic neoblasts. by Jordi Solana (499882)

“…<p>(A) Quantification of mitosis by counting of h3p-positive cells in whole mount immunohistochemistry on <i>control(RNAi)</i> and <i>Smed-not1(RNAi)</i> animals 5, 10, 15 and 20 days after RNAi (N = 7 per time point). No significant differences are detected. …”

Dynamics of major immune cell populations in the mouse CNS during <i>T</i>. <i>regenti</i> infection. by Tomáš Macháček (3406469)

“…<b>(E–H)</b> The relative proportion of the examined immune cell populations in the spinal cord (E), the brain stem (F), the cerebellum (G), and the hemisphere (H). …”

Detection of Antibodies in Blood Plasma Using Bioluminescent Sensor Proteins and a Smartphone by Remco Arts (1896490)

Inhibition of myosin IIB activity increases the number and length of filopodia-like protrusions. by Jennifer L. Hodges (207936)

“…MIIB knockdown produces many long protrusions branching from the spine head, which results in spine head positioning away from the spine tip, E. MIIB knockdown creates an increase in the fraction of thin (long protrusions with small head at tip) and filopodia-like spines (long protrusions without a spine head) with a concomitant decrease in the fraction of mushroom and stubby spines, F. …”

Synaptic remodeling and synaptic size distributions in long-term experiments. by Adiel Statman (638527)

“…Data is shown after smoothing with a 5 time point window to decrease the effects of measurement noise, and after normalizing the fluorescence values by the average over the entire experiment. …”

<i>alc/AMPKβ</i> is required for maintenance of dendritic branching in Class-IV sensory neurons. by Stanislav Nagy (570925)

“…(C-E) Quantification shows no significant change in neuronal area (mm²) (D); however, knockdown of <i>alc</i> decreases both dendritic branching order (C) and branch number (E). …”

More than two decades after the introduction of Limnoperna fortunei (Dunker 1857) in La Plata Basin by M. A. Pessotto (4770456)

“…The species exhibits a high intrinsic dispersal ability (free planktonic larvae), wide tolerance to environmental factors and dispersion is potentialized by natural dispersion processes (e.g. fauna displacement) and human facilitation (e.g. commercial navigation).…”

Opposite effects of 5-HT/AKH and octopamine on the crop contractions in adult <i>Drosophila melanogaster</i>: Evidence of a double brain-gut serotonergic circuitry by Paolo Solari (582368)

“…Injection of serotonin into the brain between the interocellar area shows that brain applications of serotonin decrease the frequency of crop activity. Based on our results, we propose that there are two different, opposite pathways for crop motility control governed by serotonin: excitatory when added in the abdomen (i.e., directly bathing the crop) and inhibitory when supplied within the brain (i.e., by injection). …”

Different types of history-dependent behavior one might observe. by Denise M. Wolf (272435)

“…This gives the observer the impression of first an increase in information and memory and then a decrease as the trajectories approach their long-term values. d,e) If measurements are made on single cells rather than on averaged populations (as we did in this paper), history-dependent distributions may be observed. d) Short-term stochastic memory. …”

Behavior of the minimal molecular model of SIN asymmetry establishment. by Archana Bajpai (127253)

“…Solid lines for molecules at old SPB, dashed lines for molecules at new SPB, time in arbitrary units. (<b>B–E</b>) Timing of transition (reaching the inflection point in the SIN_New curve) greatly depends on total level of each of the investigated proteins (plotted on a log₂ scale). …”

The model develops larger place fields with shallower phase precession in areas of higher running speed. by Eloy Parra-Barrero (15461005)

“…There is a tendency for a modest decrease as the mean of the distribution (dotted line) is below a ratio of 1. …”