Clonal interference plays a prominent role in the dynamics of adaptation. by Daniel J. Kvitek (222988)

“…Mutations that are at a lower allele frequency in the final time point than at an earlier time point (i.e. below the y = x line) have decreased due to interference from a competing lineage. …”

Duration of topically applied antibodies in the vagina. by Jessica G. Cole (368927)

Data_Sheet_1_Immediate and long-term electrophysiological biomarkers of antidepressant-like behavioral effects after subanesthetic ketamine and medial prefrontal cortex deep brain... by Matthew Bergosh (18854590)

“…</p>Results<p>We found that the depression-like behavioral and weight effects of CORT correlated with a decrease in aperiodic-adjusted theta power (5–10 Hz) and an increase in sample entropy during the administration phase, and an increase in theta peak frequency and a decrease in the aperiodic exponent once the depression-like phenotype had been induced. …”

Bmi1 is down-regulated in the aging mouse brain. by Mohamed Abdouh (181282)

“…The blue line represents the mean, and the red line represents the standard deviation (n = 15; **<i>P</i><1.022E⁻²⁴). …”

Data_Sheet_1_The pre-ejection period is a highly stress dependent parameter of paramount importance for pulse-wave-velocity based applications.docx by Niklas Pilz (14618465)

“…Mental stress decreases the PEP by 16% (mean 90.0 ms) while physical stress halves PEP (mean 53.9 ms). …”

Use of GPCR-HIT to show effect of AT₁ receptor activation on CCR2/Gα_i1 proximity. by Mohammed Akli Ayoub (176430)

“…It has been observed previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref039" target="_blank">39</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref041" target="_blank">41</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref042" target="_blank">42</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref044" target="_blank">44</a>] that the BRET signal can increase or decrease as a consequence of the ligand-induced conformational change associated with Gα_i1 protein activation (A). …”

Effect of corticosterone and/or LBP treatment on SVZ and hippocampal neurogenesis. by Benson Wui-Man Lau (205109)

“…Data are expressed as mean±SEM. Scale bars: A-C & E-G: 50 µm; I-K: 25 µm.…”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

Table 1_Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings.do... by Mostafa M. Rady (14004633)

“…<p>Abiotic stress significantly damages crops, reducing global yields by over 50%. Among these challenges, salt stress poses a critical constraint that severely affects the growth, productivity, and quality of soybeans in various regions worldwide. …”

Overview of the SEB model. by Joseph A. Heng (21175983)

“…However, these biases are reduced in the case of high capacity. The crossover point between under- and overestimation increases with the variance of the numerosity distribution. c) Illustration of the coefficient of variation (i.e., SD[]/E[]) for different capacities. …”

CAF inhibit melanoma invasion in GOF^Notch1 mice. by Hongwei Shao (493627)

“…Arrows point to invading tumor cells. Percentage of invasion is based on results of H&E staining in low power fields (LPF) of each tumor section. …”

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…(B) The number of bands of bridging fibrosis per high power field were counted in images obtained at 100× magnification after Sirius red staining. There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…<p>(<b>A</b>) Proximity ligation assay for the analysis of ILK/kindlin-1 interaction in COLXVI and mock control cells (scale bar equals 50 µm). …”

Influence of Experimental Thermal Shifts and Overcrowding on Fecundity in Wild Females of Acartia Tonsa of the Bahía Blanca Estuary by Berasategui Anabela Anahi (10476259)

“…We examined the influence of thermal shift (6 ± 1ºC and 18 ± 1ºC) and overcrowding stress on egg production and hatching success in wild females of A. tonsa of the Bahía Blanca Estuary. Egg production rate (EP), hatching success during seven days (E7 %) and time taken to hatch 50 % of eggs (T 50) were registered. …”

HDACIs-induced inhibiton of <i>Gnrh1</i> gene transcription. by Lu Gan (33435)

“…There is no difference among the groups (n>10, One-way ANOVA). (E) HDACIs inhibited <i>Gnrh1</i> gene transcription rather than decreased the stability of <i>Gnrh1</i> mRNA. …”

Probiotics regulate Toll-like receptor (TLR) pathway in the lung 24 hours post CLP. by Ludmila Khailova (337471)

“…<p>Reverse transcription and real-time PCR assays were performed to quantify steady-state mRNA levels of TLR-2, TLR-4, MyD88 and NFΚB (p50/p105). (A) TLR-2 and (C) MyD88 were significantly upregulated in the septic group compared to shams (P<0.05) and significantly downregulated in the lungs of LGG and BL treated septic mice compared to untreated septic mice. …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Furthermore this increase in [Ca²⁺]_c is associated with a reduction in ΔΨ_m. Application of 50 mM KCl induces a further rise in [Ca²⁺]_c and profound mitochondrial depolarisation. …”

How Stable Are 2H-MoS₂ Edges under Hydrogen Evolution Reaction Conditions? by Nawras Abidi (9089558)

“…Hence, we suggest that the 50%S S-edge evolves over time toward a 0%S S-edge, covered by surface OH that will block permanently the active sites.…”

Time course of activity levels in middle-aged female mice. by David R. Bonsall (813770)

“…Mice showed reduced maximum velocity in their movement, both (E) on the wheel and (F) when placed in a novel environment. …”