DLK inhibition on low dose nocodazole treatment impacts gene expression. by Laura DeVault (798362)

“…Conversely, nocodazole treatment decreases expression of biological processes specific to mature neuronal behaviors including Pain Perception, Behavior Regulation and Feeding Behavior (Sensory Perception of Pain (GO:0019233, NES = 2.3965, p = <2.2e-16, FDR = 0.008895), Regulation of Behavior (GO:0050795, NES = 2.29, p = <2.2e-16, FDR = 0.01129), Neurotransmitter Transport (GO:0006836, NES = 2.3623, p = <2.2e-16, FDR = 0.00975), G-protein Coupled Receptor Signaling (GO:0007187, NES = 2.6953, p = <2.2e-16, FDR = <2.2e-16) and Feeding Behavior (GO:0007631, NES = 2.772, p<2.2e-16, FDR<2.2e-16)). …”

Supplementary Material for: Fric Test Revisited: A Suggestion for a New Scoring System and Its Correlation with Urticaria Control Test and Dermatology Life Quality Index by Can P.K. (5817772)

Table_3_Individual patient-centered target-driven intervention to improve clinical outcomes of diabetes, health literacy, and self-care practices in Nepal: A randomized controlled... by Shahina Pardhan (841338)

“…</p>Methods<p>A total of 110 participants with newly and consequently diagnosed Type 2 were randomly allocated into intervention (mean age = 45 ± 9.7 years) and control (mean age = 47 ± 12.5 years) groups. …”

Table_1_Individual patient-centered target-driven intervention to improve clinical outcomes of diabetes, health literacy, and self-care practices in Nepal: A randomized controlled... by Shahina Pardhan (841338)

“…</p>Methods<p>A total of 110 participants with newly and consequently diagnosed Type 2 were randomly allocated into intervention (mean age = 45 ± 9.7 years) and control (mean age = 47 ± 12.5 years) groups. …”

Table_2_Individual patient-centered target-driven intervention to improve clinical outcomes of diabetes, health literacy, and self-care practices in Nepal: A randomized controlled... by Shahina Pardhan (841338)

“…</p>Methods<p>A total of 110 participants with newly and consequently diagnosed Type 2 were randomly allocated into intervention (mean age = 45 ± 9.7 years) and control (mean age = 47 ± 12.5 years) groups. …”

TRLS2^-/- mice demonstrate appropriate hormone responses to low blood glucose. by Daniel W. Fisher (4872406)

“…Tukey’s <i>Post Hoc</i> Test p < 0.05) are decreased in <i>Trls2</i>^-/- mice. <b>G)</b> H&E sections (40x) of thyroid gland morphology is similar between <i>Trls2</i>^+/+ and <i>Trls2</i>^-/-, without signs of swollen follicles or dysplastic epithelial cells. …”

The development of the glomerulocystic phenotype is progressively associated with loss of primary cilium. by Anna Iervolino (708944)

“…<p>Representative pictures of renal cortex from 50 days old Ctr (B) and Dicer cKO mice (A, C, D) stained for α-Acetylated Tubulin (green) and counterstained with Dapi (blue). …”

Small molecule inhibitors of GSK-3β impede VEEV replication. by Kylene Kehn-Hall (45085)

“…<p><b>A</b>) U87MG astrocytes were treated with BIO (10, 5, 2.5, or 1.25 µM) and cell viability assayed 24 hours later by CellTiter Glo Assay (Promega). …”

Triptolide induces tRXRα degradation and AKT inactivation through activation of p38. by Na Lu (325317)

“…Triptolide-induced time-dependent phosphorylation of p38, JNK and Erk1/2 was compared to its effect on decreasing AKT phosphorylation and PARP cleavage. (B) HepG2 cells were treated with 50 nM triptolide for 9 h with or without p38 inhibitor SB203580 (10 µM), JNK inhibitor SP600125 (10 µM) or Erk1/2 MAPK inhibitor PD98059 (10 µM). …”

Id2 down regulation drives Neuro2a AD cells towards the AI phenotype. by Lina Chakrabarti (501389)

“…(<b>H</b>) Representative bands from Western blot analysis revealed over activation of Akt, Raf, Erk and Smad pathways and overexpression of Integrin β1 protein in AD cells after Id2 down regulation indicating activation of anoikis resistant pathways. Data points represent mean ± S.D. (n = 4–6). *p<0.04 and **p<0.0001 by Student’s t-test. …”

Radiation limits the effect of OSM induction on IL-6 secretion but enhances the effect of RCCS. by Jake Goyden (748034)

“…With OSM treatment (C), irradiation without RCCS decreased IL-6 secretion at all time points. Irradiation had no effect on the synergistic increase in IL-6 secretion seen with combined OSM induction and RCCS. …”

Quantification of PLN sinus volume capacity (SVcap) using CE-US. by Echoe M. Bouta (456220)

“…In contrast, the increased SV could not be quantified following saline injection, which decreased US signal throughout the LN. (E) FPsi (arbitrary units; a.u.), SV (mm³), SV signal intensity (SVsi; a.u.), and SV Capacity (SVcap; a.u.) were calculated for the DEFINITY^® injected mouse with Amira as described in Materials and Methods. …”

Simulation results of rate-dependent APD changes in six different conditions. by Young-Seon Lee (565899)

“…<p>APs were drawn in the steady-state condition at the pacing rates of 2 Hz (A) and 1 Hz (B). (C) The relationships between APD and BCL were drawn at the control condition (<b>a</b>), I_CaL decreased by 50% (<b>b</b>), 70% (<b>c</b>), I_K1 increased by 100% (<b>d</b>), the PeAF condition with I_CaL decreased by 50% (<b>e</b>), and the PeAF condition (<b>f</b>) with I_CaL decreased by 70%.…”

Data_Sheet_1_Influence of Older Age and Other Risk Factors on Pneumonia Hospitalization in Switzerland in the Pneumococcal Vaccine Era.docx by Werner C. Albrich (3177693)

“…Older age with both age cut-offs were associated with increased LOS (≥50 years: aRR: 1.19 and 1.24, respectively; age ≥65 years: aRR: 1.60 and 1.20, respectively; p < 0.001 for all) and mortality (≥50 years: aOR: 4.73 and 2.84, respectively; age ≥65 years: aOR: 2.38 and 2.69, respectively, p < 0.001 for all) in patients with a pneumonia and pneumococcal pneumonia diagnosis, respectively. …”

Characteristics induced by 2 weeks exposure of SRA01/04 cells to low-doses of H₂O₂. by Zi-Feng Zhang (341807)

“…<p>A. Shows that cell viability (Left) of SRA01/04 cells decreases with increasing concentrations of H₂O₂ as measured by the MTT assay (Mean± SD; n = 5.). …”

Impaired cαβT cell development in <i>Rpt</i>^<i>f/f</i><i>-Foxn1Cre</i> mice. by Hong-Xia Wang (288934)

“…</b> Bar graphs represent mean ± SEM of CD4 and CD8 T cell (10d, <i>n</i> = 3; 6w <i>n</i> = 4). …”

Effects of WNT5A isoform expression on cancer cell line proliferation. by Matthieu Bauer (388805)

“…WNT5A-S increases while WNT5A-L decreases proliferative rates. Data (mean ± SEM from triplicate determinations) from a representative experiment are shown. …”

SNX-3-mediated CIE recycling tubules do not converge into the classical EEA-1-labeled sorting endosomes. by Yangli Tian (4871416)

“…[ROI] = 16, n = 12. Error bars are mean ± 95% CI. ns, not significant (Student’s <i>t</i> test). …”

Diagram illustrates the potential actions of Astragaloside IV on Fas/Fas L apoptotic pathway. by Mi Hye Kim (543923)

Fig-7. The development of the glomerulocystic phenotype is progressively associated with loss of primary cilium. by Anna Iervolino (6712642)

“…<div>Fig-7 Representative pictures of renal cortex from 50 days old Ctr (B) and Dicer cKO mice (A, C, D) stained for α-Acetylated Tubulin (green) and counterstained with Dapi (blue). …”