Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

“…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”

Treatment of cancer cells with FL118 significantly decreases BrdU positive cells (proliferative cells) and induces apoptotic markers. by Xiang Ling (307318)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

Subjects:

Silencing of SphK1, but not SphK2, decreases HPAEC migration by S1P in wound healing ECIS assay. by Evgeny V. Berdyshev (307465)

Inhibition of PI3K activity decreases uptake of Opa_CEA-expressing gonococci via CEACAM1. by Maike Voges (154488)

Table_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.DOCX by Kai Yang (73590)

Image_1_Decreased Vessel Density in Retinal Capillary Plexus and Thinner Ganglion Cell Complex Associated With Cognitive Impairment.TIF by Kai Yang (73590)

T310A mutation decreases TSP50’s ability to interact with NF-κB:IκBα complex and to promote NF-κB signaling. by Yu-Yin Li (323887)

Growth of <i>Spirulina</i> spp. at 450nm for different temperature. by Maha Rehman (17114332)

HPK1-IN-3 decreased T lymphocyte activation. by Min Jeong Ahn (18886882)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

Overexpression of ZnT3 and ZnT10 decreases ROS and prevents Ang II-induced senescence. by Nikolay Patrushev (179006)

1-hr treatment with 10μM PF573228 or 10μM PD98059 in Caco-2 cells. by Sema Oncel (10152053)

Subjects:

C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”

Treatment with mitochondrial shuttle inhibitors, GKA50, Ranolazine and glucose results in significant decreases in superoxide concentration as detected by coelenterazine chemilumin... by Laura L. Bronsart (844933)

Differential gene expression assay EC₅₀ values in Huh-7 cells and PHH. by Xuan G. Luong (9761423)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…To develop more potent compounds, we initiated a structure–activity relationship study that identified 2-aminobenzoxazole as a viable scaffold. …”

Effects of H₂O₂, insulin and resveratrol on ³H -thymidine incorporation in human primary keratinocytes. by Yasuo Ido (172159)

Advancing the science of NOWS research. by Sarah E. Maylott (14560785)

“…It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. Understanding which infants will develop NOWS soon after birth could reduce hospital stays for infants who do not develop NOWS and decrease burdens on hospitals and clinicians. …”