Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway by J. Wang (472325)

“…Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC50 value of 2.24 mM. …”

Changes in the activity of caspases during exposure to PCBs. by Francesco Raggi (844655)

“…To confirm the specificity of PCB action on caspases, cells were also pre-treated with caspase inhibitors prior to PCB exposure. 20 μM Ac-DEVD-CHO (A), Ac-IETD-CHO (B) or Ac-LEHD-CHO (C) were used as inhibitors of caspase -3, -8 or -9, respectively. Data (mean ± SD of five independent experiments) were expressed as arbitrary units (A.U.); the value of 1 was attributed to the caspase activity of vehicle-exposed cells. **, p<0.001, ***, p<0.0001, compared with the vehicle, according to ANOVA followed by Dunnett’s post hoc test. ##, p<0.005, ###, p<0.0005, p = n.s. …”

Dispersion relation for the Hamiltonian hat{mathcal {H}}_0 of the π-flux cubic lattice model for different values of the parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0... by G Mazzucchi (557358)

“…</strong> Dispersion relation for the Hamiltonian \hat{\mathcal {H}}_0 of the π-flux cubic lattice model for different values of the parameter <em>a</em> (from top to bottom, <em>a</em> = 0, 0.5, 1).</p> <p><strong>Abstract</strong></p> <p>We study the superfluid properties of attractively interacting fermions hopping in a family of 2D and 3D lattices in the presence of synthetic gauge fields having π-flux per plaquette. …”

Fig. S5 from A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-κB Signaling in <i>KRAS</i>-Mutant Colon Cancer Cells by Akira Inoue (6273)

“…<p>Supplementary Figure S5. Evaluation of the toxicity of super carbonate apatite-MIRTX conjugate and effect of systemic administration of formulated MIRTX on tumor growth in vivo. …”

Tree cover limits occupancy of a declining game bird by Bradley Kubecka (7387181)

“…Only 2 of 144 sites were characterized by low-moderate canopy cover (<50%) with a moderate fire frequency (burned 5 and 7 times since 2010). …”

Water temperature affects aggressive interactions in a Neotropical cichlid fish by Manuela L. Brandão (5021027)

A trend in discussions about the endemic blues and daily responsibilities. by Seoyoung Kim (2603596)

Associations of baseline BK and hyp3-BK(1–8) with change in cortical interstitial fractional volume [Vv(Int/cortex)] in the 66 participants assigned to placebo, the 63 participants... by Kevin M. Wheelock (4237609)

“…Values above the dashed lines reflect an increase in Vv(Int/cortex) and those below the lines a decrease over 5 years.</p>…”

Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling by Heejin Ahn (3173670)

Establishment and characterization of a choroid plexus barrier system. by Bethany A. O’Hara (8532741)

“…<p>A) Barrier development protocol. Cells are maintained at high density (>50% confluence) and used for experiments between passages 30–38. …”

RovA stimulated transcription of its own gene. by Yiquan Zhang (113213)

“…<p>Only the bacterial cells of “shift from 26 to 37°C” at the middle-exponential growth phase were analyzed herein. <b>a) LacZ fusion.</b> A promoter-proximal region 743 bp upstream to 146 bp downstream of <i>rovA</i> was cloned into pRW50 containing a promoterless <i>lacZ</i> reporter gene, and then transformed into WT or <i>ΔrovA</i> to determine the β-galactosidase activity in cellular extracts. …”

The impact of the single exit price policy on a basket of generic medicines in South Africa, using a time series analysis from 1999 to 2014 by Rajatheran Moodley (7109351)

“…</p><p>Results</p><p>Majority of the medicines analysed reflect a substantial decrease in medicine prices immediately after implementation of the pricing regulations as reflected in both the change in level and the change in slope using the interrupted time series analysis.…”

Mass-spectrometry results of HA-tagged TBP55 co-immunoprecipitation. by Han Jiang (195350)

Change in smooth muscle NO from a dynamic increase in flow. by William Davis Haselden (9175156)

“…<p>Simulations were performed using a static proximal model with a NO production rate in the parenchyma of 0.02 M/s corresponding to 50% GC activity with no flow. …”

<i>A</i>. <i>fumigatus</i> siderophores protect <i>A</i>. <i>fumigatus</i> biofilm from <i>P</i>. <i>aeruginosa</i> anti-fungal activity. by Gabriele Sass (335744)

The physiological role of I_Cl(Ca) during membrane depolarization was examined using NPPB and T16A_inh-A01. by Ji Hyun Jeon (112239)

“…The half-maximal dose (EC₅₀) of T16A_inh-A01 that was necessary to increase the width was similar to EC₅₀ of T16A_inh-A01 that inhibited I_Cl(Ca) (2.6 vs. 3.0 µM). …”

Meth induces a biphasic and depressive effect on cardiac electrophysiology. by Jimmy Zhang (159595)

LIR1 deficiency markedly reduces <i>L</i>. <i>amazonensis</i> virulence. by Maria Fernanda Laranjeira-Silva (843978)

Image3_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.TIF by Meng-meng Liu (18241785)

Image4_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.TIF by Meng-meng Liu (18241785)