TCF7L2 Genetic Variants do not Influence Insulin Sensitivity or Secretion Indices in Autoantibody-positive Individuals at Risk for Type 1 Diabetes by Maria J. Redondo (9640512)

The coevolution of effort and replication, replicated and corrected by Florian Kohrt (13918527)

“…</p> <p>The results of this corrected model show the following pattern: Starting with a high effort, low effort replications are more attractive than conducting novel research (that is, employing this strategy received higher payoffs), which results in the replication rate reaching nearly 100% after ~730,000 steps. At this point the decline of effort has made low-effort novel research more attractive than low-effort replications (because publishing a novel positive result is associated with a higher payof than publishing a replication) and consequently the replication rate decreases again. …”

Hybrid wind-diesel-battery system planning considering multiple different wind turbine technologies installation by Rakhshani, E.

“…Results of the case study demonstrate a significant reduction in the planning cost, namely above 5 percent depend on the wind speed. Furthermore, the total yearly energy generated by diesel generator is decreased by 700 kWh, meaning higher renewable penetration and less emissions.…”
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Comparison of neurogenic activity between levodopa and PPX in MTPT-treated PD animals. by Jin Young Shin (116728)

“…MK-801 administration significantly increased the number of BrdU-positive cells in the SVZ of the levodopa-treated PD mice compared to the levodopa-only PD animals (A and B), whereas no significant changes in neurogenic activity were observed in the PPX-treated PD animals following the administration of MK-801 (A and B).Values are means ± SD (n = 5, *P<0.02; **P<0.002). Scale bar: 20 µm.…”

RIPostC induced myocardial autophagy. by Zhihua Han (28856)

“…After 3 hours of perfusion, RIPostC increased the ratio of LC3-II/LC3-I and the expression of Beclin-1, decreased SQSTM1 expression in ND group. Data were presented as means ± SEM, n = 5 per group. …”

Effects of tPA on cerebral infarction and hemorrhage at 18 h after reperfusion. by Mitsunori Ishiguro (359127)

“…*P<0.05 vs. vehicle (Welch's <i>t</i> test, n = 5–8). Data are expressed as means ± SEM.</p>…”

Degradation of PKM2 by BQ exposure. by Jie Zhu (126574)

“…Values are presented as means ± SDs (n = 3−5). *, <i>P</i><0.05; **<i>P</i><0.01; #, <i>P</i><0.001 compared with controls.…”

Mesenchymal ablation at e13.5 leads to reduced β- and acinar-cell mass due to impaired proliferation of precursor cells. by Limor Landsman (206879)

“…<p><i>Nkx3.2</i>-Cre;DTR embryos and non-transgenic (non tg) littermates were injected with DT at e13.5 and analyzed at the embryonic days indicated. (A) A scheme illustrating embryonic development from e9.5 to e18.5. …”

Alternation of RNA levels of synaptic proteins and dendritic spines in hTDP-43_WT homozygous mice. by Ya-Fei Xu (85380)

“…(<b>B–C</b>) The numbers of dendritic spine are dramatically reduced in the brain of TDP-43 hemozygous mice compared to NT mice. Data shown are the means ± SEM of 3–5 mice per group; **p<0.001, as assessed by one-way ANOVA with Tukey’s posthoc analysis or Two-tailed student’s t test to compare measures among 2 groups.…”

Dose-Response Curves by Karen Lipkow (380366)

“…<div><p>CheA activity (orange) was increased in ten equal steps from steady-state to maximum level to mimic an increasing repellent concentration (A–D) or decreased to mimic an increase in attractant (E–H). …”

Developmental changes in intrinsic membrane properties of hESMNs. by Tomonori Takazawa (316965)

“…(B) Resting membrane potential and (C) rheobase did not change (n  = 27 and 29, respectively). Positive current steps were injected in 5 pA increments to distinguish small differences in rheobase among individual neurons. …”

Synthesis, Structure, and Activity of Enhanced Initiators for Olefin Metathesis by Jennifer A. Love (1393678)

“…A series of ruthenium olefin metathesis catalysts of the general structure (H₂IMes)(PR₃)(Cl)₂RuCHPh (H₂IMes = 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene) have been prepared; these complexes are readily accessible in two steps from commercially available (H₂IMes)(PCy₃)(Cl)₂RuCHPh. …”

Docking of LDCVs Is Modulated by Lower Intracellular [Ca²⁺] than Priming by Mathias Pasche (74950)

“…The parameters that reflect docking, i.e. axial mobility and the fraction of LDCVs residing at the plasma membrane for less than 5 seconds, were strongly decreased at a free [Ca²⁺]_i of 500 nM. …”

Omniscan-induced cells express iron metabolism proteins. by Chhanda Bose (787135)

“…<p><b>(A)</b> Expression of ferroportin and other iron regulatory protein hepcidin by human PBMC treated with 0.5 mM Omniscan and deferiprone for 8 days, as shown by immunocytochemistry staining. …”

The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane by Rizk, Nasser M

“…Methodology: C57BL/6 mice (n=20) were fed with a high fat diet (60%) for 16 weeks to generate diet induced obese (DIO) mice with body weights between 45–50 gm. …”
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Rapamycin prevented death from renal dysfunction in <i>Tsc2</i>^{Δ<i>podocyte</i>}. by Wakiko Iwata (8600457)

“…<p>(<b>A</b>) <i>Tsc2</i>^{Δ<i>podocyte</i>} mice treated with rapamycin had improved survival compared to vehicle-treated <i>Tsc2</i>^{Δ<i>podocyte</i>} mice. …”

Mutation of <i>pgl</i> reduces nucleotide output. by Jisun Kim (837555)

“…Changes >1.-5fold and P<0.05 are shown. Graphs display means and standard deviations of carbon labelled sum. n = 3. …”

Zyflamend, a unique herbal blend, induces cell death and inhibits adipogenesis through the coordinated regulation of PKA and JNK by Dexter Puckett (9282362)

Table_1_Network Reconfiguration Among Cerebellar Visual, and Motor Regions Affects Movement Function in Spinocerebellar Ataxia Type 3.DOCX by Hui Chen (28597)

“…At the nodal level, the clustering coefficient and local efficiency increased significantly in the visual (bilateral cuneus) and sensorimotor (right cerebellar lobules IV, V, VI) networks and decreased in the cognitive areas (right middle frontal gyrus). …”

Table_3_Network Reconfiguration Among Cerebellar Visual, and Motor Regions Affects Movement Function in Spinocerebellar Ataxia Type 3.docx by Hui Chen (28597)

“…At the nodal level, the clustering coefficient and local efficiency increased significantly in the visual (bilateral cuneus) and sensorimotor (right cerebellar lobules IV, V, VI) networks and decreased in the cognitive areas (right middle frontal gyrus). …”