Response of a representative cell. by Taekjun Kim (302640)

“…Spike density following S1–S2 sequence was compared with spike density following S2 for each of temporal epochs of 30 ms with a shift of 5 ms. The temporal epochs with a statistically-significant decrease in spike density as determined with Mann-Whitney U-test are shown in blue bars, and significant increase in red bars, centering on corresponding analysis windows, revealing the magnitude and time course of suppressive and facilitative effects of S1 that depend on S1 position and SOA. …”

Dietary Restriction Induces Gluconeogenic Gene <i>pck-2</i> Expression via DAF-16, and <i>pck-2</i> Expression is Needed for DR-associated Healthspan Benefits. by Brian Onken (86790)

“…<p>(A) Representative wild-type animals expressing a GFP transcriptional reporter for <i>pck-2</i> (<i>pck-2</i> promoter GFP fusion, lacking <i>pck-2</i> coding sequences) under <i>ad libitum</i> (AL) or dietary restricted (DR) conditions, day 4 of life. …”

Influence of Additional Gaussian Noises on Mixed Quantum-Classical Nonadiabatic Dynamics Simulations of Photoisomerization of <i>cis</i>-Azobenzene by Zihan He (3702544)

The <i>TgCRT</i>-deficient parasites displayed a swollen vacuole and a disrupted endolysosomal system. by L. Brock Thornton (6808385)

“…The TgCPL staining was used to assess the morphology of the VAC. The mean VAC size ± standard error of mean (SEM) was calculated for three independent measurements and is listed in the figure. …”

Data_Sheet_1_Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex.docx by Ingrid Nogueira (15407156)

“…When comparing individual firing properties, noise exposure differentially affected type A and B PC firing frequency in response to depolarizing current steps. Specifically, type A PCs decreased initial firing frequency in response to +200 pA steps (p = 0.020) as well as decreased steady state firing frequency (p = 0.050) while type B PCs, on the contrary, significantly increased steady state firing frequency (p = 0.048) in response to a + 150 pA step 1 week after noise exposure. …”

Column charts of SI_8min and SI_10min in the therapy and control group at follow-up. by Felix L. Herr (21544362)

Column charts of WiAUC in therapy and control group at baseline and follow-up. by Felix L. Herr (21544362)

Fluorescence detection of cellular toxicity as a function of starvation or treatment with the mTOR inhibitor, XL-765. by Kara R. Vogel (739629)

The perimeter of L2 cell dendritic trees after silencing <i>Tor</i>, <i>Atg5</i> and <i>Atg7</i> genes. by Ewelina Kijak (3746299)

“…<p>After silencing the <i>Tor</i> (A) or <i>Atg5</i> (B) under control of the 21D-promoter, the daily rhythm of the L2 cell dendritic tree size was abolished (mean +/- SD) [<i>Tor</i>: ANOVA, p>0.05; <i>Atg5</i>: Kruskal-Wallis Test: H (3, N = 401) = 7,722824 p =, 0521], while in case of <i>Atg7</i> (C), the pattern of the daily rhythm of the L2 dendritic trees was changed. …”

Excess glucose availability negatively impacts healthspan of young and old animals; conversely, the benefits of disrupting glycolysis do not include extended maximal lifespan. by Brian Onken (86790)

“…Exposure to excess glucose results in significant decreases in swimming rates in young animals (day 5 from hatching; <i>P</i> = 0.0004, unpaired t test). n = 40 animals per condition from a single trial; error bars represent SEM; *** <i>P</i> < 0.001. …”

Comparison of oxidized proteins extracted from HL-1 cells exposed to LG, NG, HG and IHG between short- (12h) and long-time (72h) glucose treatment. by Patrick Mordel (17020879)

PDRN upregulates SIRT1 protein expression in HaCaT cells exposed to UVB or H₂O₂. by Jingjing Chen (293564)

Development of Prolinol Containing Inhibitors of Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design by Dianne T. Keough (4660351)

“…Against <i>TBr</i> in cell culture, a prodrug exhibited an EC₅₀ of 10 μM. …”

The KOR antagonist BTRX-335140 blocks U-69,593 responses in mPFC-projecting VTA dopamine neurons. by Elyssa B. Margolis (7933838)

Table_5_Bacillus velezensis B105-8, a potential and efficient biocontrol agent in control of maize stalk rot caused by Fusarium graminearum.DOCX by Shuang Wang (46453)

“…Microbial biocontrol agents are the best means of controlling MSR and reducing the use of chemical fungicides, such as Bacillus spp.…”

3‑Hydroxypyridin-4(1<i>H</i>)‑one Derivatives as <i>pqs</i> Quorum Sensing Inhibitors Attenuate Virulence and Reduce Antibiotic Resistance in <i>Pseudomonas aeruginosa</i> by Zhi-Ying Miao (9388615)

“…The most potent derivative <b>16e</b> was identified as a selective inhibitor of the <i>pqs</i> system (IC₅₀ = 3.7 μM) and its related virulence factor pyocyanin (IC₅₀ = 2.7 μM). …”

Comparison of ATP production in HL-1 cells exposed to LG, NG, HG and IHG between short- (12h) and long-time (72h) glucose treatment. by Patrick Mordel (17020879)

Curcumin restores aging-induced disruption of the BTB in mice by activating autophagy in mouse testes injected with D-gal. by Chen Xue (699418)

Decision trees to evaluate the fecal microbiota after SCI. by Ruizhu Lin (6820649)

<i>pals-25</i> is required for increased <i>pals-5p</i>::<i>GFP</i> expression in <i>pals-22</i> mutants. by Kirthi C. Reddy (250928)

“…<p>(A-E) Mutants isolated from <i>pals-22</i> suppressor screens show decreased expression of the <i>pals-5p</i>::<i>GFP</i> reporter. …”