Estimation of the CO and CBF. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

Pre-post effects of a tetanus care protocol implementation in a sub-Saharan African intensive care unit by Riaz Aziz (5702639)

“…Despite the increased provision of care, we found no significant decrease in overall mortality in the Early versus the Late groups (55.4% versus 40.3%, p = 0.069), or between the pre-protocol and post-protocol groups (60.7% versus 50.0%, p = 0.28). …”

GSTM3 A/B Polymorphism and Risk for Head and Neck Cancer: A Meta-Analysis by Yu Xu (52257)

“…Stratification by tumor site indicated that the GSTM3 polymorphism was associated with a decreased risk of laryngeal cancer under recessive model and homozygote comparison (OR = 0.52, 95%CI: 0.30–0.89; and OR = 0.50, 95%CI: 0.29–0.87, respectively); By stratifying source of control, decreased cancer risk was observed in hospital-based population under all genetic models (OR = 0.67, 95%CI: 0.56–0.81 for the dominant model; OR = 0.66, 95%CI: 0.46–0.95 for the recessive model; OR = 0.55, 95%CI: 0.37–0.83 for the homozygote comparison model, and OR = 0.70, 95%CI: 0.58–0.84 for the heterozygote comparison model).…”

Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing <i>Iso</i>combretastatins and Phenstatins as Antitumor Agents by Yanqing Pang (4386715)

“…Most of these selenium containing hybrids exhibited potent cytotoxicity against a panel of cancel cell lines, with IC₅₀ values in the submicromolar concentration range. …”

<i>PsnWRKY95</i> transgenic plants selection and functional analysis of <i>PsnWRKY95</i> in cadmium resistance. by Yuzhao Ma (12840632)

Demonstration that SP-1 and SP-3 negatively regulates the PP2A-Aα promoter. by He-Ge Chen (90952)

“…Expression of the exogenous pCMV-SP-1 in both types of ocular cells attenuated expression of the endogenous gene coding for PP2A-Aα. F. Expression of the exogenous SP-3 in both types of ocular cells induced only slight decrease in the luciferase reporter gene activity within 0 to 500 ng of the pCMV-SP-3 plasmid, which is not statistically significant. …”

Image5_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

DOT or SAT for Rifampicin-resistant tuberculosis? A non-randomized comparison in a high HIV-prevalence setting by Erika Mohr (3331566)

“…<div><p>Background</p><p>Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administered treatment (SAT) in a South African township with high rates of RR-TB and HIV.…”

Plasmid constructs used in this study. by Zahra Hosseininia (22265113)

“…We found that hypermethylation of the upstream regulatory sequence of PRAME-AS results in an approximately 50% reduction in PRAME transcripts and an 18.5% decrease in PRAME-AS transcript levels. …”

Oligonucleotides used in this study. by Zahra Hosseininia (22265113)

“…We found that hypermethylation of the upstream regulatory sequence of PRAME-AS results in an approximately 50% reduction in PRAME transcripts and an 18.5% decrease in PRAME-AS transcript levels. …”

Meta-Analysis: Effects of Probiotic Supplementation on Lipid Profiles in Normal to Mildly Hypercholesterolemic Individuals by Mikiko Shimizu (205878)

“…Probiotic interventions (including fermented milk products and probiotics) produced changes in total cholesterol (TC) (mean difference –0.17 mmol/L, 95% CI: –0.27 to –0.07 mmol/L) and low-density lipoprotein cholesterol (LDL-C) (mean difference –0.22 mmol/L, 95% CI: –0.30 to –0.13 mmol/L). …”

Table 5_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic... by Weifeng Zhen (12969341)

“…Ultra-protective ventilation (≤4 mL/kg predicted body weight) has the potential to further decrease ventilator-induced lung injury but may result in severe hypercapnia. …”

CA alleviated DOX-induced myocardial injury <i>in vitro</i> and <i>in vivo</i>. by Meijiao Mao (10677555)

IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…(C) and (D) Western blotting showing the relationship between the phosphorylation of FOXO3a and <i>PRNP</i> expression. Treatment with 50 and 100 ng/ml IGF-1 remarkably increased the phosphorylation of FOXO3a in both the SH-SY5Y and HeLa cell lines but caused little variation in the total level of FOXO3a. …”

Meta-analyses of the association of <i>G6PC2</i> allele variants with elevated fasting glucose and type 2 diabetes by Yuanyuan Shi (563992)

“…Per increment of G allele at rs560887 and A allele at rs573225 resulted in a FG 0.070 mmol/l and 0.075 mmol/l higher (ß (95% CI) = 0.070 (0.060, 0.079), <i>p</i> = 4.635e-50 and 0.075 (0.065, 0.085), <i>p</i> = 5.856e-48, respectively). …”

P2RX7 is overexpressed in metastatic ovarian carcinoma tumors. by José David Nuñez-Ríos (18823719)

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

Baseline characteristics of study subjects. by Arlete Gianfaldoni (17655603)

“…To detect LH and FSH pulses, the technique proposed by Santen and Bardin was adopted; therefore, one pulse was defined as a 20% increase in the concentrations as to the preceding point, followed by an important decrease.…”

S1 File - by Arlete Gianfaldoni (17655603)

“…To detect LH and FSH pulses, the technique proposed by Santen and Bardin was adopted; therefore, one pulse was defined as a 20% increase in the concentrations as to the preceding point, followed by an important decrease.…”