Data_Sheet_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Pred... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Image_5_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Image_2_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_2_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Image_1_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_3_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Table_4_Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts... by Gemma A. Foulds (315263)

“…Although chemotherapy had no effect on the percentage of Treg, MDSC and NK cells, the expression of inhibitory receptors CD85j, LIAR and NKG2A and activating receptors NKp30 and NKp44 on NK cells increased, concomitant with a decreased expression of NKp46 and DNAM-1 activating receptors. …”

Specific knock-down of HIF-1α in MSPCs but not in ECFCs inhibits vessel formation <i>in vivo</i>. by Nicole A. Hofmann (138477)

“…A significantly decreased capacity to form perfused vessels was found in implants containing shHIF-1α transfected MSPCs compared to untreated co-transplants. …”

Human vessel formation after progenitor co-transplantation depends on hypoxia-induced factors in MSPCs but not ECFCs. by Nicole A. Hofmann (138477)

“…Human mesodermal origin was visualized with anti-human vimentin monoclonal antibody staining (h.Vimentin, brown; mouse and human nuclei counterstained with hematoxylin, blue; third row; scale bar 50 µm). Plugs contain different numbers of h.Vimentin-negative infiltrating mouse CD45⁺ hematopoietic cells (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044468#pone.0044468.s006" target="_blank">Figure S6C</a>). …”

<i>NOTCH3</i> Variants and Risk of Ischemic Stroke by Owen A. Ross (139522)

“…</p> <p>Results</p><p>Sequencing of the 269 SWISS probands identified one (0.4%) with small vessel type stroke carrying a known CADASIL mutation (p.R558C; Exon 11). Of the 19 common <i>NOTCH3</i> variants identified, the only variant significantly associated with ischemic stroke after multiple testing adjustment was p.R1560P (rs78501403; Exon 25) in the combined SWISS and ISGS Caucasian series (Odds Ratio [OR] 0.50, P=0.0022) where presence of the minor allele was protective against ischemic stroke. …”

Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection. by Olga A. Maximova (3115716)

“…Note: (i) pial lymphocytic infiltration (yellow arrows) appeared at 7 dpi (<b>G</b>), increased at 14 dpi (<b>H</b>), and decreased at 21 dpi (returning to the level seen at 7 dpi) (<b>I</b>); (ii) a rare focal lesion (red asterisk in H) with depleted MAP2-IR in the Purkinje cell layer (PCL), granule cell layer (GrCL) neurons, and partially in the molecular layer (ML) is spatially associated with the increased pial lymphocytic infiltration. …”

Coordinated polarity induced by high flow triggers vessel regression. by Claudio A. Franco (124909)

“…Scale bars (<b>A</b>: 50 μm; <b>E</b>: 20 μm). The data used to make this figure can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002125#pbio.1002125.s001" target="_blank">S1 Data</a>.…”

Simplified depiction of hyperthermia impacts on the intrafollicular complement and coagulation cascade. by Louisa A. Rispoli (8201232)

“…Alpha-2-Macroglobulin (A2M) is an anti-proteinase that complexes with proteinases such as kallikrein [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0227095#pone.0227095.ref050" target="_blank">50</a>] to inhibit proteolytic activity.…”

DataSheet1_Conservation status and historical relatedness of South African communal indigenous goat populations using a genome-wide single-nucleotide polymorphism marker.docx by T. C. Chokoe (13217025)

“…The use of Illumina goat SNP50K BeadChip shows that there was a migration route of communal indigenous goat populations from the northern part (LP) of South Africa to the eastern areas of the KZN that confirmed their historical relatedness and coincides with the migration periods of the Bantu nation.…”

Table_1_The beneficial effect of sulforaphane on platelet responsiveness during caloric load: a single-intake, double-blind, placebo-controlled, crossover trial in healthy particip... by Hidde P. van Steenwijk (16499940)

“…Participants carrying the polymorphic variant NAD(P)H dehydrogenase quinone 1 (NQO1*2) showed decreased excretion of sulforaphane (p = 0.035).</p>Conclusion<p>Sulforaphane was shown to be effective in targeting platelet responsiveness after a single intake. …”

In Patients with Established RA, Positive Effects of a Randomised Three Month WBV Therapy Intervention on Functional Ability, Bone Mineral Density and Fatigue Are Sustained for up... by Alessandra Prioreschi (2609719)

“…Hip BMD was significantly reduced in the CON group (0.97(0.05) to 0.84(0.05) g.cm^-2, p = 0.01), while no decreases were seen in the WBV group (1.01(0.05) to 0.94(0.05) g.cm^-2, p = 0.50). …”

Image_1_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Moreover, the JK5G group had a lower incidence of anemia (63.33% vs. 13.33%, p < 0.001), decreased lymphocyte count (20.00% vs. 0%, p = 0.010), decreased appetite (53.33% vs. 16.67%, p = 0.003), nausea (33.33% vs. 6.67%, p = 0.010), and asthenia (30.00% vs. 6.67%, p = 0.017) than the control group. …”

Image_2_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Moreover, the JK5G group had a lower incidence of anemia (63.33% vs. 13.33%, p < 0.001), decreased lymphocyte count (20.00% vs. 0%, p = 0.010), decreased appetite (53.33% vs. 16.67%, p = 0.003), nausea (33.33% vs. 6.67%, p = 0.010), and asthenia (30.00% vs. 6.67%, p = 0.017) than the control group. …”

CD14⁺ monocytes inhibit IFN-α production triggered by Ab-RSV via TLR7 in pDC. by Marcel A. Schijf (461275)

“…<p>(<b>A</b>) IFN-α production in CD14⁺ cell depleted PBMCs induced by Ab-RSV complexes, TLR9 ligand ODN 2216 and TLR7 ligand imiquimod is decreased by blocking endosomal acidification with 50nM Bafilomycin A₁. …”