Identification of the class of mediators present in the hvKP1 generated conditioned minimal medium and ascites that enhance the growth and/or survival of hvKP1. by Thomas A. Russo (188770)

“…<p>The growth of hvKP1 was assessed at 0, 3, 6, and 24 hours in human ascites (batch 1). <u>Panel A</u>: Ascites was not supplemented (unconditioned) or supplemented with: 1) 5% hvKP1-generated conditioned (cond) ascites (batch 1) or 2) 50% conditioned ascites generated from the <i>E. coli</i> laboratory strain BW25113 and isogenic derivatives deficient in the production of enterobactin (BW25113Δ<i>entB</i> (CGSC#8704), BW25113Δ<i>entC</i> (CGSC#8702)), AI-2 molecules (BW25113Δ<i>luxS</i> (CGSC#10100)), and indole (BW25113Δ<i>tnaA</i> (CGSC#8309)) (batch 1). …”

Supplementary Material for: Gonadotropin-Releasing Hormone Agonists During Gonadal Chemotherapy for the Effect on Pregnancy Outcome and Ovarian Function in Premenopausal Patients W... by Yuan Y. (3237453)

“…For secondary endpoints, the GnRHa group improved menstrual recovery rates (RR=1.20; 95% CI: 1.11-1.30), and decreased the rate of amenorrhea 1-2 years after chemotherapy (RR=0.50; 95% CI: 0.40-0.63). …”

MVEC:AoAF interactions are dependent on signaling through ALK5. by Rebecca A. Scott (488956)

“…(<b>F</b>) Following treatment with 1 μM A83-01, the number of total cells, MVECs, and AoAFs per mm³ was decreased compared to control cultures on day 14. …”

DataSheet1_40Ar/39Ar ages and geochemistry of the Intersalar Range of the Bolivian Altiplano: A volcanological transect spanning the arc and reararc of the Central Andean Plateau.x... by Morgan J. Salisbury (13896744)

“…In this study we report 23 new ⁴⁰Ar/³⁹Ar ages, 15 whole-rock Sr-Nd-Pb isotope analyses, and 50 whole-rock major and trace element analyses from samples collected across ∼115 km of the Intersalar Range. …”

DataSheet_1_Balancing the Risk-Benefit Ratio of Immune Checkpoint Inhibitor and Anti-VEGF Combination Therapy in Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.docx by Li Tao (154250)

“…To optimize clinical decision-making, we conducted a systematic review and meta-analysis of published randomized clinical trials to characterize the efficacy and the risk of adverse events (AEs) in patients treated with ICIs plus anti-VEGF therapy.…”

HrrF expression is iron-responsive and Fur-dependent. by Estevan A. Santana (621708)

“…<p><b>A.</b> Total RNA was purified from strains 86-028NP<i>rpsL</i>, 86-028NP<i>rpsL</i>Δ<i>fur</i>, 86-028NP<i>rpsL</i>Δ<i>fur</i>Δ<i>hrrF_L,</i> and 86-028NP<i>rpsL</i>Δ<i>fur</i>Δ<i>hfq</i> grown in DIS to mid-logarithmic phase at 37°C with shaking at 50rpm. …”

Table_1_Spike protein of SARS-CoV-2 Omicron variant: An in-silico study evaluating spike interactions and immune evasion.DOCX by Jose A. Jimenez Ruiz (14189012)

Sour taste initiates GABAergic and serotonergic inhibition in taste buds. by Yijen A. Huang (334066)

“…<b>B,</b> In another experiment, ATP secretion stimulated by sweet/bitter tastants (as in A) was strikingly diminished when a sour tastant (HAc, acetic acid 10 mM, pH 5.0) was added to the stimulus mix (↓, taste/HAc). …”

DataSheet_1_A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.... by Savannah M. Rocha (10826524)

“…Results indicated that oral administration of PT150 caused a dose-dependent decrease in replication of SARS-CoV-2 in lung, as well as in expression of ACE2 and TMPRSS2. …”

Data_Sheet_1_Associations of healthy eating index-2015 with osteoporosis and low bone mass density in postmenopausal women: a population-based study from NHANES 2007–2018.docx by Kai Wang (21246)

Human Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P) regulates cytoplasmic lipid droplet abundance: A potential target for indirect-acting anti-dengue virus agents by Anastasia Hyrina (3860455)

“…Pre-treatment of Huh-7.5.1 cells with PF-429242 results in a dose-dependent inhibition of DENV infection [median inhibitory dose (EC₅₀) = 1.2 microM; median cytotoxic dose (CC₅₀) = 81 microM; selectivity index (SI) = 68)] and a ~3-log decrease in DENV-2 titer with 20 microM of PF-429242. …”

The effectiveness of substance use interventions for homeless and vulnerably housed persons:  A systematic review of systematic reviews on supervised consumption facilities, manage... by Olivia Magwood (5819663)

Table_3_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Image_1_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Table_1_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Table_2_Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial.PDF by Mads N. Thomsen (13270053)

“…</p>Methods<p>In order to determine the additional effect of carbohydrate restriction in addition to a fixed body weight loss, we randomly assigned 72 adults with T2D and obesity (mean ± SD HbA_1c 7.4 ± 0.7%, BMI 33 ± 5 kg/m²) to a carbohydrate-reduced high-protein diet (CRHP; energy percent from carbohydrate/protein/fat: 30/30/40) or an isocaloric conventional diabetes diet (CD; 50/17/33) for 6 weeks. …”

Table 1_Efficacy of encapsulated fecal microbiota transplantation and FMT via rectal enema for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial (CAP-E... by Natsuda Aumpan (9449957)

“…Primary endpoint was clinical response defined by ≥50-point decrease in IBS-symptom severity score (IBS-SSS) at 4 weeks. …”

Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Image 5_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Table 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.xlsx by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”