Showing 32,861 - 32,880 results of 47,188 for search '(( 50 ((a decrease) OR (we decrease)) ) OR ( 5 ((wt decrease) OR (mean decrease)) ))', query time: 1.45s Refine Results
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  3. 32863

    Cre-mediated heterozygous deletion of Med28 causes differentiation of iPSC. by Lin Li (28817)

    Published 2015
    “…<p><b>(A)</b><i>Med28</i><sup><i>fl/fl</i></sup> iPSCs were infected with Ad-Cre, followed by single cell plating on day 3 and genotyping along with other analyses performed between days 5–8. <b>(B)</b> PCR genotyping shows clones with both deleted (- allele) and non-deleted WT (+ allele) alleles infected with Ad-Cre (+ Cre) compared to uninfected clones (-Cre), respectively. …”
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  8. 32868

    Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... by Francisco Alejandro Lagunas-Rangel (13849122)

    Published 2025
    “…In colorectal cancer cell lines, decreased PI3K phosphorylation was at least partially attributable to mevalonate depletion, a known consequence of statin treatment.…”
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  13. 32873

    Presentation_1_Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.pptx by Charles Drummer (4533508)

    Published 2023
    “…</p>Methods<p>To examine this hypothesis, we performed liver pathological analysis, RNA-seq, FACS, Western blots, Seahorse mitochondrial stress analyses of macrophages and bone marrow transplantation on HFD-induced NAFLD in WT and Casp11–/– mice.</p>Results and Discussion<p>Our results showed that 1) HFD increases body wight, liver wight, plasma cholesterol levels, liver fat deposition, and NAFLD activity score (NAS score) in wild-type (WT) mice; 2) HFD increases the expression of caspase-11, GSDMD, interleukin-1β, and guanylate-binding proteins in WT mice; 3) Caspase-11 deficiency decreases fat liver deposition and NAS score; 4) Caspase-11 deficiency decreases bone marrow monocyte-derived macrophage (MDM) pyroptosis (inflammatory cell death) and inflammatory monocyte (IM) surface GSDMD expression; 5) Caspase-11 deficiency re-programs liver transcriptomes and reduces HFD-induced NAFLD; 6) Caspase-11 deficiency decreases extracellular acidification rates (glycolysis) and oxidative phosphorylation (OXPHOS) in inflammatory fatty acid palmitic acid-stimulated macrophages, indicating that caspase-11 significantly contributes to maintain dual fuel bioenergetics—glycolysis and OXPHOS for promoting pyroptosis in macrophages. …”
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    Degradation of aggregate-prone αA-crystallin mutant, R116C. by Ilangovan Raju (333566)

    Published 2013
    “…The mutant R116C protein level has decreased after 6 hours treatment with cycloheximide compared to wild-type protein which demonstrated R116C protein instability. …”
  16. 32876

    ILI time-series, weighting schemes and projection targets. by Alessio Andronico (2202853)

    Published 2024
    “…For the weighting scheme v2, we used a normal distribution parameterized with the mean and the standard deviation of the observed incidence for the corresponding calendar week across the training seasons. …”
  17. 32877

    Pneumococcal RNase R globally impacts protein synthesis by regulating the amount of actively translating ribosomes by Cátia Bárria (6174782)

    Published 2019
    “…We present evidences showing that accumulation of these factors leads to a decreased amount of 70S active particles, as demonstrated by the altered sucrose gradient ribosomal pattern in the RNase R mutant strain. …”
  18. 32878

    Role of TiO2 and carbon nanotubes on polyethylene, and effect of accelerated weathering on photo oxidation and mechanical properties by Zagho M.M.

    Published 2019
    “…TONPs increased the tensile strength of the samples by 11.5% but deterioration of this property is the same as the pristine sample after accelerated weathering for 39 days. …”
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  19. 32879

    Ski7 mutant fish produce reduced numbers of developing offspring. by Luis Enrique Cabrera-Quio (10164691)

    Published 2021
    “…(F) Quantification of embryo development in <i>WT</i> and <i>ski7</i><sup><i>-/-</i></sup> embryos. …”
  20. 32880

    Recruitment of the cellular Osh/ORP proteins is facilitated by Fis1 into tombusvirus replication compartment. by Wenwu Lin (7542863)

    Published 2021
    “…Each experiment was repeated. (D) Decreased level of re-localization of ergosterols to internal punctate structures in fis1Δ yeast replicating TBSV (third panel from left) in comparison with WT yeast (bottom panel) or fis1Δ yeast expressing Fis1p from a plasmid (right panel). …”