Schematic representation of the effects of stepwise bromination of the benzene ring of benzotriazole (Bt), including interdependence of the molecular volume (A) and pK_a (B) of the products with their IC₅₀ for inhibition of protein kinase CK2α: (a) Green arrows follow sequential bromination of the central vicinal C(5)/C(6) atoms, leading to a moderate decrease of pK_a and a large decrease in IC₅₀; (b) Red arrows illustrate the lesser effects of bromination of the peripheral C(4)/C(7) atoms, resulting in a significant decrease of pK_a, with virtually no gain in inhibitory activity; (c) Black lines link products with the same number of bromine atoms, but substantially differing in pK_a and IC₅₀, culminating in the di- and tri-brominated derivatives with inhibitory activities comparable to that of TBBt. by Romualda Wąsik (119538)

Effects of specific anti-miRs for the five miRNAss on the IC50 of cisplatin (A) and paclitaxel (B) in Hec1A cells. by Taek Sang Lee (494682)

Ulk2 morphants have a decreased extension/retraction ratio. by Stacey Lee (647217)

RNF5 loss decreases ERK and Akt activation, CDK1 and Smo expression and KSHV lytic replication in PEL cells. by Xiaojuan Li (351842)

Neutralization of JRFL WT and mutant viruses by different MAbs and CD4-IgG2. by Chitra Upadhyay (817121)

“…A) Titration curves of representative virus-MAb pairs. B) JRFL WT and mutant neutralization by MAbs targeting V2i, V3, V2q, and the CD4bs and by CD-IgG2. …”

Temporal distributions of inscriptions and occupations using uniform 50-years-long timeblocks. by Vojtěch Kaše (6156971)

Resveratrol decreases cell proliferation in a time and dose dependent manner. by Mehtap Kilic Eren (591048)

Development of a cAMP sensor with decreased pH sensitivity. by Katy L. Everett (461878)

Expression of genes encoding proteins involved in protein folding, quality control, trafficking and ER-associated degradation differentially expressed in liver of <i>Fmo5</i><sup><... by Ian R. Phillips (5074121)

The <i>P[syt^P-L]</i> mutation decreases the Ca²⁺ affinity of release and vesicular release probability, but the readily releasable pool is unchanged. by Mallory C. Shields (4474210)

“…<p>(A) Mean EJP amplitudes from <i>+/-;P[syt^WT]/+</i> (filled black circles) and <i>+/-;P[syt^P-L]/+</i> (filled red circles) larvae at Ca²⁺ levels ranging from 0.05 mM—5.0 mM. …”

Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer by Ana Alfaro (280118)

“…Interestingly, when analyzing only the HPV16-positive CC, D2 increases (OR = 2.5, 95% CI = 1.2–5, p < 0.05) and D3 decreases (OR = 0.45, 95% CI 0.2–0.9, p < 0.05) the risk to develop CC before 50 years old in relation with A1/2 variant. …”

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

Average time necessary to disperse 50% of the population introduced (half-life time) in experiments and theoretical simulations, according to the number of woodlice initially intro... by Pierre Broly (228993)

Lack of PD-L1 expression by host tissues increases numbers of activated donor T cells but decreases donor Tregs in spleen. by Mohammad S. Hossain (415643)

NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4. by Zhentao Sheng (107495)

“…(C) Expression of WT Psid rescued the level of N-Drk-GFP in <i>psid-D4</i> mutant clones. …”

Western blot analysis of LET-60 levels in WT and <i>let-60</i> mutants. by Maximilian Kramer-Drauberg (8981141)

Western blot analysis of MPK-1 levels in WT and <i>let-60</i> mutants. by Maximilian Kramer-Drauberg (8981141)

Drugs IC₅₀s data during the study period. by Winnie Okore (14139712)

Diversity of intestinal microbiota in the feces of finishing pigs fed a diet supplemented with or without <i>B</i>. by Jun Ho Song (1675123)

Immunization for EAE decreased the counts of CD4+ and CD8+ T-PBLs in DA rats. by Mirjana Nacka-Aleksić (3342095)