DataSheet_1_Anti-diabetic combination therapy with pioglitazone or glimepiride added to metformin on the AGE-RAGE axis: a randomized prospective study.pdf by Eugenio Ragazzi (2211859)

“…Within pioglitazone group, as well within glimepiride group, significant variations (Δ, as difference between 5 years of treatment minus basal) were observed for AGE (Δ= ˗21.1±13.4 µg/ml, P<0.001 for pioglitazone; Δ= ˗14.4±11.4 µg/ml, P<0.001 for glimepiride) and in AGE/s-RAGE (Δ= -0.037±0.022 µg/pg, P<0.001 for pioglitazone; Δ= -0.024±0.020µg/pg, P<0.001 for glimepiride), suggesting an average decrease of the parameters by more than 50% in both treatments. …”

Supplementary file 1_Instability and uncertainty of carbon storage in karst regions under land use change: a case study in Guiyang, China.docx by Heng Zhou (287510)

“…By 2035, projections under natural development, urban expansion, and ecological protection scenarios estimate increases to 147.50 Tg, 147.40 Tg, and 147.82 Tg, respectively. (2) Carbon storage instability increased from 2000 to 2020, while uncertainty is expected to decrease by 2035. …”

Image_2_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

Image_1_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

This study examines a range of drugs targeting different cellular functions in three bacterial species, using various system-level readouts to analyze their effects. by Morten Kals (19727515)

“…This novel link between morphology change and growth inhibition led us to develop a new heuristic metric, MOR₅₀, which can be used for rapid and high throughput MIC estimation. …”

Image_1_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

Efficacy & safety of <i>Carica papaya</i> leaf extract (CPLE) in severe thrombocytopenia (≤30,000/μl) in adult dengue – Results of a pilot study by Dipu T. Sathyapalan (8468901)

“…<i>25</i> and IFNγ: 1.93% v/s 62.6% for; <i>p = 0</i>.<i>12</i>). While a mean percent increase in IL-6 levels occurred in placebos (15.92%±29.93%) by day 3, a decrease was noted in CPLE group (12.95%±21.75%; <i>p = 0</i>.…”

Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey by John Ly (2901986)

“…</p><p>Conclusions</p><p>We detected a 30% decreased odds of FBD after the start of EVD in a rural Liberian county with relatively few cases. …”

DataSheet1_Techno-Economic and Environmental Assessment of Ammonia Production From Residual Bagasse Gasification: A Decarbonization Pathway for Nitrogen Fertilizers.pdf by Rodrigo Oliveira Telini (12874529)

“…Finally, since 1.6 Mt_CO2/y can be avoided by using the residual bagasse as feedstock in the ammonia plant, the alternative scenarios become competitive vis-à-vis the conventional scenario in terms of NPV when carbon taxes of 40–50 USD/t_CO2 are adopted. …”

DataSheet_1_Intensive Hemodiafiltration Successfully Removes Ganciclovir Overdose and Largely Exceeds Reported Elimination During Hemodialysis—A Case Report and Review of the Liter... by Verena Gotta (4040870)

“…Since the product label reports a 50% decrease of ganciclovir plasma concentrations after intermittent hemodialysis (HD), two HDF sessions were considered necessary to achieve a ≥75% elimination of the drug by precaution, despite targeted intense HDF prescription. …”

DataSheet_1_Exploring blood lipids-immunity associations following HBV vaccination: evidence from a large cross-sectional study.pdf by Qian Yang (300330)

“…</p>Results<p>After adjusting for relevant covariates, we observed that low levels of high-density lipoprotein cholesterol (HDL) were independently linked to a significantly lower seroprotective rate. …”

Table_1_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_2_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_1_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_2_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Analysis of targeted MLX deletion in Sertoli cells. by Patrick A. Carroll (11586792)

“…(<b>K</b>) Comparison of the decrease in DSP rate between WT to MLX^KO and MLX^fl/fl to MLX^fl/fl with Amh-Cre (<i>N</i> = 5–7). …”

Datasheet1_5′-UMP inhibited muscle atrophy due to detraining: a randomized, double-blinded, placebo-controlled, parallel-group comparative study.docx by Mika Inoue (19133983)

“…</p>Results<p>Both groups showed a significant decrease in muscle thickness at MT70. …”

Virus titers in the lung of vaccinated and control mice after challenge with A/Puerto Rico/8/1934 (H1N1) virus. by Anne-Cécile V. Bayne (405631)

Unmasking the efficacy of Skipjack Tuna (<i>Katsuwonus Pelamis</i>) dark muscle hydrolyzate in lipid regulation: a promising component for functional food by Fangfang Huang (821089)

“…Furthermore, KPHs-AL exerted a combined effect of regulating lipid accumulation in FAA-induced steatosis HepG₂ cells, leading to decreased total cholesterol (TC) and total triglyceride (TG). …”

Table_1_Favourable Lifestyle Protects Cognitive Function in Older Adults With High Genetic Risk of Obesity: A Prospective Cohort Study.DOCX by Huamin Liu (6852678)

“…This study aims to confirm the association of phenotypic and genetic obesity with cognitive impairment and the benefits of adhering to a healthy lifestyle. This prospective study included 10,798 participants (aged ≥ 50 years) with normal cognitive function from the Health and Retirement Study in the United States. …”