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6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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486
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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487
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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488
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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489
GLB1 increases expression in HGPIN and a subset of PCa and correlates with decreased proliferation and increased expression of HP1γ.
Published 2015“…Data are mean +/- 95% confidence intervals. * p<0.001. <b>(A)</b> Epithelial GLB1 expression is significantly increased in HGPIN and cancer compared to benign prostate in both nuclear and cytoplasmic compartments (All p<0.0001). …”
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490
Decrease in cleavage score by randomly permuting string-of-beads vaccines.
Published 2020“…<p>(a) For each vaccine in the Pareto frontier of each bootstrap, we created 50 new string-of-beads by randomly permuting its epitopes and compared the cleavage scores of the two vaccines. …”
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491
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Subset of selected genes showing a ≥2-fold change decrease of expression in the <i>furA</i>-turning off strain AGcoaRFurA.
Published 2016“…<p>Subset of selected genes showing a ≥2-fold change decrease of expression in the <i>furA</i>-turning off strain AGcoaRFurA.…”
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498
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Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG.
Published 2013“…(C) An estimation of overall neurogenesis based on the total number of BrdU-positive cells that survived the 42-day period multiplied by the proportion of BrdU-positive cells that acquired a mature neuronal phenotype indicates an age-induced significant and abrupt decrease in the overall number of new neurons. *** <i>p</i> < 0.001 between 1.5 and 3 months and between 3 and 6 months. …”