Direct ionizing radiation and bystander effect in mouse mesenchymal stem cells by Amanda Nogueira-Pedro (12377818)

“…</p> <p><b>Conclusions:</b> The results can be interpreted as a positive outcome, meaning that the radiation damage is restricted to the directed IR MSCs not leading to off-target cell responses.…”

Responses to auditory or visual shape stimuli in the AC. by Manabu Ogi (7460417)

“…<p>(A) Image of responses to a pure tone at 5 kHz in the right AC (R5kHz). …”

Identification of sFasL mediating the inhibition of IL-1β release. by Vanessa Beynon (153924)

“…<p>a) Microarray analysis was performed in memory T-cells cultured in the presence of monocytes with and without IFNβ for 16 h and resorted by gating on CD3+CD4+7AAD- cells, upregulated candidates that fit the criteria of presence of a soluble form and molecular weight of 23–38 kDa are displayed; b) qPCR confirmation of upregulation of SSP1, LGALS9, APOL1 and FasL mRNA expression through incubation with IFNβ (n = 3); c) analysis of biological relevance of upregulated molecules by the use of blocking antibodies (10 ug/ml), only blockage of FasL significantly decreased the inhibitory effect on IL-1β release (n = 3) (% suppression calculated as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039576#pone-0039576-g004" target="_blank">Fig 4</a>); d) soluble FasL levels were measured with a FasL specific ELISA in the supernatants of co-cultured activated CD4+CD45RO+ memory T-cells (n = 3); e) surface expression of FasL is measured after overnight co-culture by staining with FasL specific antibody and acquisition of cells by flow cytometry (representative of 3 independent experiments); f) IL-1β release is inhibited by recFasL in the presence of a crosslinking antibody (n = 3) (Data are shown as means ± SD of duplicate cultures; *p<0.05, **p<0.01, ***p<0.001 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations).…”

Image_3_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.jpeg by Benjamin Jurek (322560)

“…<p>Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. …”

Table_1_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.pdf by Benjamin Jurek (322560)

“…<p>Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. …”

Mathematical modeling of nuclear deformation and architecture reorganization. by Sungrim Seirin-Lee (7372355)

“…(<b>H</b>) The deformation degrees for (<b>E</b>) and (<b>G</b>), measured by means of the deformation-related area from a circle of the same area.…”

Image_1_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.tif by Benjamin Jurek (322560)

“…<p>Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. …”

Image_2_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.tif by Benjamin Jurek (322560)

“…<p>Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. …”

Novel isoguanine derivative of unlocked nucleic acid—Investigations of thermodynamics and biological potential of modified thrombin binding aptamer by Weronika Kotkowiak (793451)

“…<div><p>Thrombin binding aptamer (TBA), is a short DNA 15-mer that forms G-quadruplex structure and possesses anticoagulant properties. …”

Data_Sheet_1_Becoming authoritarian for the greater good? Authoritarian attitudes in context of the societal crises of COVID-19 and climate change.docx by Magdalena Hirsch (9124524)

“…While authoritarian disposition captures general tendencies to accept the means, trust in science serves as a proxy for the perceived importance of COVID-19 and climate change mitigation. …”

Differential impacts of 61 cytokines on hybrid cell development in crude BM cultures. by Shuo Geng (488618)

“…The samples were examined in a semi-automated fashion for surface expression of CD11c, MHC II, and Ly6G. …”

Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn²⁺ Chelation by Ann-Sofi Johansson (168577)

“…Taken together, these observations point at a case where the toxic response of cultured cells might not be related to human pathology but stems from the intrinsic limitations of a simplified cell model. …”

Gamma irradiation effects on polymethyl methacrylate by Al-Qaradawi, I. Y.

Get full text
Get full text

Effects of TIIA on apoptosis-related factors after SCI. by Xin Yin (149454)

“…<p>The protein expression of Bcl-2 was reduced in the SCI group at 1 day and 3 days compared to the sham and sham/TIIA groups, whereas Bcl-2 was up-regulated in the SCI/TIIA group (A). The analyzed data are shown. (B) The cleaved caspase-3 expression began to increase at 1 day, peaked at 3 days and quickly reduced to a lower level at 7 days after SCI. …”

Acetone recovery in laboratories wastes: an approach of aspects of management, operation and environmental efficiency by Guilherme Furlan Coletti (7291532)

“…<p></p><p>The objective of this work was to exclusively improve the management of wastes constituted mainly by organic solvents, due to the opportunities for improvements in the processing of such substances in the institution where the studies were realized. By means of the tests carried out in the distillation system using acetone as a reference, advantages and disadvantages were found with increasing/decreasing the temperature used in the process. …”

Validation of the cell model. by Ling Teng (317759)

“…The halide permeability (p) is the rate of SPQ dequenching. The graphs show a deeply decreased activity in G551D-CFTR expressing cells. …”

PQ-treatment causes energy stress <i>in vivo</i> and activates energy sensing pathways. by Michael P. Siegel (195229)

“…<p>PCr/ATP ratio decreases with PQ treatment (A, with representative MR spectra above) and the ratio of phosphorylated AMPK to total AMPK increased (B, with representative western blot above). …”

USP7 increases the protein levels and stabilities of CRY1 and CRY2. by Arisa Hirano (2636251)

“…Quantified data are shown as means + SEM (n = 3). <b>D.</b> <i>Usp7</i> knockdown decreased the starting levels of CRYs-LUC. …”

NAD redox balance and expression of SIRT1 in hippocampi of mice undergoing 2- or 4-mo moderate treadmill running. by Stefano Falone (301445)

“…Both the NAD redox ratio and the SIRT1 protein level were decreased in an age-dependent fashion (S4 vs S2) (panels a and b, respectively). 2-mo exercise reduced both the NAD⁺/NADH ratio and the expression level of SIRT1 (E2 vs S2) (panels a and b, respectively), whereas both the NAD redox balance and the protein level of SIRT1 increased after 4-mo exercise (E4 vs S4) (panels a and b, respectively). …”

High mutual cooperation rates in rats learning reciprocal altruism: The role of payoff matrix by Guillermo E. Delmas (6169820)

“…<div><p>Cooperation is one of the most studied paradigms for the understanding of social interactions. Reciprocal altruism -a special type of cooperation that is taught by means of the iterated prisoner dilemma game (iPD)- has been shown to emerge in different species with different success rates. …”