Labile Iron Pool assessment of rat peritoneal macrophages through Calcein AM Assay. by James R. Connor (332038)

“…When calcein binds to iron the fluorescent activity is quenched, thus more available iron is reported as decreased fluorescent activity. All data shown are means ± SEM of three independent observations in separate cell culture wells. …”

Effect of probenecid on biopterin levels in the blood and urine after 6RBH₄ administration. by Akiko Ohashi (3202062)

“…The blood and urine were collected as in experimental procedure (A) of Materials and Methods. (a) Blood BP (lower panel) and the BH₄% (upper panel), “BH₄ alone” (open circles) and “BH₄ + Pbc” (closed circles). …”

Precocious closure of the critical period for juvenile ODP in PSD-93 KO mice. by Plinio D. Favaro (6157709)

“…<p>(A-H) Optically imaged activity and retinotopic maps in V1 of WT (A–D) and PSD-93 KO mice (E-H) during mid CP (−4), color-coded maps of retinotopy (bottom rows), histogram of OD scores (top right of panels), and color-coded OD maps (bottom right, including average ODI) are illustrated. …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. …”

LBP increased the viability of H₂O₂ treated cells in an appropriate concentration. by Bing Qi (492962)

“…H₂O₂ treatment significantly decreased the viability of SRA01/04 cells, however in the presence of LBPs (concentration of 200–400 mg/L), the induction of cell death was blocked in a dose-dependent manner. …”

Table_1_Intramolecular Annulation of Gossypol by Laccase to Produce Safe Cottonseed Protein.DOCX by Lin Wang (11986)

“…These results indicate a novel detoxification pathway for gossypol and reveal the crucial role played by radical species in cyclization. …”

Lengthened ependymal cilia and increased ciliary beating function and frequency in the Katnal2-KO brain. by Ryeonghwa Kang (6793046)

“…(<i>n</i> = 60 beads from 4 mice [WT-AD], 39, 4 [WT-AV], 62, 4 [KO-AD], 33, 4 [KO-AV], 116, 4 [WT-PM], and 82, 4 [KO-PM], Student’s <i>t</i>-test [AV bead speed], Mann-Whitney test [AD bead speed, PM bead speed]). (H) A decreased speed of microbeads in AD + AV regions after a 10-min pretreatment of brain slices with pneumolysin (PNML; 0.5 μg/ml) (<i>n</i> = 40 beads from 3 mice for pneumolysin and control [without pneumolysin] groups, Mann–Whitney test). …”

DataSheet1_Knockout of AMPKα2 Blocked the Protection of Sestrin2 Overexpression Against Cardiac Hypertrophy Induced by Pressure Overload.PDF by Nan Zhang (46264)

“…</p><p>Methods and results: Sesn2 expression was significantly increased in mice hearts at 2 and 4 weeks after aortic banding (AB) surgery, but decreased to 60–70% of the baseline at 8 weeks. Sesn2 overexpression (at 3, 6, and 9 folds) showed little cardiac genetic toxicity in transgenic mice. …”

DataSheet2_Knockout of AMPKα2 Blocked the Protection of Sestrin2 Overexpression Against Cardiac Hypertrophy Induced by Pressure Overload.PDF by Nan Zhang (46264)

“…</p><p>Methods and results: Sesn2 expression was significantly increased in mice hearts at 2 and 4 weeks after aortic banding (AB) surgery, but decreased to 60–70% of the baseline at 8 weeks. Sesn2 overexpression (at 3, 6, and 9 folds) showed little cardiac genetic toxicity in transgenic mice. …”

Effect of plasma free fatty acid supply on the rate of ceramide synthesis in different muscle types in the rat by Piotr Zabielski (4568062)

“…<div><p>Ceramide is a key compound in sphingolipid metabolism. Dynamics of ceramide synthesis is important in the several biological processes, such as induction of apoptosis or insulin resistance. …”

ANAC078 negatively regulates auxin synthesis by directly binding to the promoters of <i>YUC2</i>, <i>YUC4</i> and <i>GH3</i>.<i>5</i>. by Yong Tang (161879)

“…<p>A. qPCR analysis confirmed the expression of <i>ANAC078(-C)</i> in WT [<i>ANAC078(-C)ox</i>] (left), which results in the decreased IAA amount (right). …”

Reduced expression of Np9 in NCCIT teratocarcinoma cells increases sensitivity to chemical stress. by Susana M. Chan (6411794)

“…Reduced expression of Np9 resulted in increased sensitivity to bleomycin or cisplatin treatment with decreased viability of NCCIT cells. T bars denote the standard deviations of the means; P values were determined using student t-test analysis. ns not significant, *<i>P</i><0.05, **<i>P</i><0.001, ***<i>P</i><0.0001.…”

Expression change of olfactory sensory system genes in sex determination gene mutants. by Jun Xu (45543)

“…<p>(A) Relative mRNA expression levels of <i>BmPBP1</i>, <i>BmPBP2</i>, <i>BmPBP3</i>, <i>BmOR1</i>, <i>BmOR2</i>, and <i>BmOR3</i> in WT and mutant males. …”

c-Kit deficiency impairs reconstitution of HSPCs in the adult mice. by Yuki Kimura (199693)

“…<p>(A) c-Kit deficiency decreases hematopoietic stem cell subsets. …”

Vitamin D₃-induced VC and the expression of bone related genes in the aortas of wild type mice. by Min-Su Han (83764)

“…Data are group means ± SD of experimental groups (n=6-8). Statistical analysis was performed using the unpaired Student’s <i>t</i>-test. …”

Effect of Tyrphostin AG490 on signal transducer and activator of transcription 3 (STAT3) activation. by Mojca Gasparitsch (8138415)

“…Values are means ± s.e. of at least three independent experiments <b>(a)</b>. …”

Pdx1 effects on cell viability and Pdx1 internalization. by Vincenzo Cardinale (781191)

“…When cells were treated with 0.5 μM Pdx1, cell viability significantly decreased after 48 hours in both hBTSCs and HepG2 as observed by Trypan blue exclusion assay (data are means ± SD of 6 experiments; **p< 0.01; ***p< 0.001). …”

CystC and Δ14CystC inhibit NMuMG cell proliferation and invasion by Jonathan P Sokol (27257)

“…CystC and Δ14CystC both significantly decreased DNA synthesis in resting NMuMG cells (*< 0.05; Student's -test). …”

DataSheet_1_HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.docx by Mohammed Ghiboub (9463586)

“…Cytokine and gene expression analyses confirmed that IFNγ-treated macrophages consistently develop a cytokine response after LPS repeated challenge, but pretreatment with HDAC3i or HDAC3 siRNA reinstates a state of tolerance reflected by general suppression of tolerizable genes, possibly through decreasing TLRs expression, and particularly TLR4/CD14. …”

DataSheet2_So Similar, yet so Different: The Case of the Ionic Liquids N-Trimethyl-N (2-methoxyethyl)ammonium Bis (trifluoromethanesulfonyl)imide and N,N-Diethyl-N-methyl-N(2-metho... by Oriele Palumbo (5342030)

“…The two ILs, slightly differing only for the length of two short chains, diverge significantly in the thermal properties: N111(2O1)-TFSI undergoes to a crystallization upon cooling, whereas N122(2O1)-TFSI is likely to become a glass. …”