AbM-induced secretion of IL-1β depended upon the NLRP3 inflammasome. by Tsung-Teng Huang (167578)

“…<p>(<b>A</b>) THP-1 cells were stably transfected with shRNAs targeting ASC and NLRP3, and mRNA expression of ASC and NLRP3 was measured by RT-PCR and compared with nontarget control (shCtrl). …”

Hydrogel Skin-Covered Neurons Self-Assembled with Gustatory Cells for Selective Taste Stimulation by Trang Huyen Le-Kim (7011074)

“…This work demonstrated that agarose gel skin is a simple, fast, and effective means to increase the signal selectivity of cellular responses in the co-culture of multiple types of cells.…”

Viability results after long-lasting ischemia and reperfusion. by Zsolt Turóczi (5657446)

“…Also, viability after 9 hours of ischemia and 2 hours of reperfusion decreased significantly compared to the 9-hour-ischemia-only group. …”

Macrophages facilitate reactivation by the secretion of extracellular vesicles (EVs). by Raffael Júnio Araújo de Castro (3875755)

“…<p>(<b>A</b>) Experimental design scheme of the transwell assay. …”

Table 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Background<p>Hypertensive heart disease (HHD) poses a substantial global public health burden, particularly among older adults. …”

Table 4_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Background<p>Hypertensive heart disease (HHD) poses a substantial global public health burden, particularly among older adults. …”

Image 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.tif by Ning An (618997)

“…Background<p>Hypertensive heart disease (HHD) poses a substantial global public health burden, particularly among older adults. …”

Table 3_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Background<p>Hypertensive heart disease (HHD) poses a substantial global public health burden, particularly among older adults. …”

Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Background<p>Hypertensive heart disease (HHD) poses a substantial global public health burden, particularly among older adults. …”

³¹P NMR spectra of Myo-pHis. by Mehul V. Makwana (13570466)

“…<p>a) Phosphorylation of histidines in myoglobin i) Native myoglobin, pH 10.8; ii) Myo-pHis, pH 10.8, following phosphorylation with potassium phosphoramidate, buffer exchange to pH 10.8, and concentration (18.2 mg/mL); iii) Denatured myo-pHis. …”

GLP-1 effects on insulin secretion, proliferation and apoptosis are impaired in insulin receptor knockdown cells. by Nunzia Caporarello (221943)

“…<p>Panel A. Insulin secretion in INS-1E cells, transfected with insulin receptor siRNA. …”

Central <i>Dusp6</i> expression is not affected by changes in body composition or nutrition. by Katrin Pfuhlmann (4413625)

“…<p>Decreased body weight (A) and food intake (B) but unchanged levels of <i>Dusp6</i> mRNA in brain areas (C) of chow-fed Lep^ob mice treated daily for 6 days with 1 mg/kg of leptin (Leptin) and chow-fed Lep^ob mice treated with saline but pair-fed (Saline pf) to the Leptin group, compared to ad libitum fed saline controls (Saline <i>ad lib</i>) (n = 5–6 mice; food intake: n = 3 cages). …”

POMC and NPY neurons of <i>Ugcg</i>^{f/f//CamKCreERT2} mice are less responsive to leptin. by Viola Nordström (388258)

“…<p>(A) Leptin engages POMC neurons in the Arc of control (<i>Ugcg</i>^f/f) mice and <i>Ugcg</i>^{f/f//CamKCreERT2} mice 1–2 wk p.i., as indicated by elevated c-Fos. …”

EA treatment restored <i>Stat</i>5NKO-induced obese phenotype, improved energy metabolism and cold tolerance in the <i>Stat</i>5NKO obese mice. by Shu-Ping Fu (549948)

“…<p>(A) Observation of body weight in the four groups, n = 10 in each group. …”

GLP-1 fails to rescue apoptosis in ENPP1 transfected cells. by Nunzia Caporarello (221943)

“…<p>Apoptosis was assessed by caspase 3/7 activity, in INS-1E (panel A) and βTC-1 (panel B) cells, either transfected with neo or ENPP-1 gene variant. …”

Chondrocyte death in the knee joints of mice with immune-complex-mediated arthritis (ICA) by Karin CAM Nabbe (58865)

“…IL-13 significantly decreased chondrocyte death, both at day 3 and at day 7 (a). …”

The effect of rosiglitazone-treated stromal cells on myeloid differentiation in HSPCs. by Wenyi Lu (701872)

“…<p>(A) C3H10T1/2 cells and M2-10B4 were treated with 10 μM rosiglitazone in the presence or absence of BADGE(20μM). …”

Positional Isomeric Effects on the Optical Properties, Multivalent Glycosidase Inhibition Effect, and Hypoglycemic Effect of Perylene Bisimide–deoxynojirimycin Conjugates by Ren-Feng Li (10688392)

“…The molecular docking results showed that the active fragment of <b>PBI-4DNJ-1</b> has the highest binding energy (9.649 kcal/mol) and the highest total hydrogen bond energy (62.83 kJ/mol), which were related to the positional isomeric effect on the hypoglycemic effect in mice. This work introduced a new means to develop antihyperglycemic agents in the field of multivalent glycomimetics.…”

Glass Formation of Null-Matrix Cu-Hf-(Zr, Ti) Alloys by Octavio Lozada-Flores (8301582)

“…The results also showed that the parameters obtained from thermal analysis did not correlate with the GFA obtained. However, a good correlation of GFA and dc was found by means of the topological model, where the highest % packing efficiency (53.57 %) was found for the Cu61.48Hf18.52Zr6.48Ti13.52 alloy, which also showed the highest dc value with 6 mm.…”

Data_Sheet_1_Improvement of Mesenchymal Stem Cell Immunomodulatory Properties by Heat-Killed Propionibacterium acnes via TLR2.PDF by Gabriela da Paz Silveira (6194351)

“…As these cells share the same MSCs bone marrow (BM) site and interact with each other, here we evaluated the P. acnes and its soluble polysaccharide (PS) effect on MSCs and their immunomodulatory role in a murine model of traumatic brain injury (TBI). …”