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901
Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance.
Published 2014“…</b> Open field tests of average swim velocity during 10 minutes of each hour through a circadian cycle, in tanks replicating lifetime husbandry conditions, show a lower mean movement at night (in either genotype, **p<0.01) but no difference between genotypes in any measure during day (p = 0.247) or night (p = 0.814).…”
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902
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903
Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH.
Published 2013“…<p><b>A.</b> Representative images showing vasospastic MCA in vehicle treated mice, as compared to larger diameter MCAs from the two simvastatin treated groups that are similar to MCA in naïve group. …”
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904
VCP inhibition induces accumulation of ubiquitinated-proteins and decreases NFκB-expression.
Published 2016“…The increase in ubiquitinated-protein accumulation in soluble protein-fraction suggests that the DDN<sup>DBeQ</sup> treatment alters VCP-function resulting in proteostasis-inhibition and ER-accumulation of these proteins. We also see a significant decrease in expression of tumor-mediator, NFκB in DDN/DDN<sup>DBeQ</sup> treated samples as compared to the control-vehicle, although DDN<sup>DBeQ</sup> was most effective as anticipated. …”
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Image_1_Electroencephalographic Evidence for Individual Neural Inertia in Mice That Decreases With Time.JPEG
Published 2022“…EEG was measured after induction of and emergence from isoflurane administered near the EC<sub>50</sub> dose for loss of righting in genetically inbred mice on a timescale that minimizes pharmacokinetic confounds. …”
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912
MiR-129-5p levels were decreased in mouse depression models.
Published 2025“…<p><b>A.</b> Experimental schedule. All mice underwent behavioral tests following CRS treatment. …”
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913
Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>.
Published 2021“…Compared with the co-culture of WT BMCs and WT calvarial cells (WT / WT), the number of osteoclasts were significantly decreased at 50% in the co-cultures of TgLRAP BMCs and TgLRAP calvarial cells (TgLRAP / TgLRAP) (graph). …”
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914
Aspirin decreases expression of NFκB and β-catenin in colon cancer cells.
Published 2013“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”
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915
Marimastat decreases hepatic stellate cell (HSC) activation, but increases recruitment of inflammatory cells.
Published 2013“…<p>Chronic carbon tetrachloride (CCl4) administration in animals treated with Marimastat resulted in a decreased activation of HSCs, as identified by alpha-smooth muscle actin (α-SMA) staining (A). …”
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