Molecular Simulations Reveal Terminal Group Mediated Stabilization of Helical Conformers in Both Amyloid-β42 and α‑Synuclein by Shayon Bhattacharya (6560891)

“…Computed free energies and interaction maps (not obtainable from experiments alone) show that flexible terminal groups (N-terminus of Aβ42 and C-terminus of αS) show a tendency to stabilize folded helical conformations in both peptides via primary hydrophobic interactions with central hydrophobic domains, and secondary salt bridges with other domains. …”

Human biliary tree stem cell (hBTSC) differentiation towards pancreatic fate induced <i>in vitro</i> by Pdx1 peptide. by Vincenzo Cardinale (781191)

“…(D) In hBTSCs cultured for 14 days in KM containing 0.1 μM Pdx1, MafA (4.5-folds) (data are means ± SD of 6 experiments; **p< 0.01) or Pdx1 (2-folds) (data are means ± SD of 6 experiments; **p< 0.01) gene expression increased in comparison with KM, while EpCAM mRNA decreased (average 4-folds) (data are means ± SD of 6 experiments; *p< 0.05).…”

Table_2_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.docx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Table_3_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.docx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_5_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Data_Sheet_3_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.xlsx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_6_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Data_Sheet_1_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.xlsx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_3_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Table_1_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.docx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_1_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_4_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Data_Sheet_2_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.xlsx by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Image_2_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

“…The KEGG results showed the enriched module for folding, sorting and degradation (chaperones and folding catalysts) and the decreased modules related to metabolisms of cofactors and vitamins, amino acid, and lipid in PSCI patients. …”

Inhibitory effect of ketoconazole, quinidine and 1-aminobenzotriazole on pharmacokinetics of <i>l-</i>tetrahydropalmatine and its metabolite in rats by Weibin Xiao (9960755)

“…Following the administration of CYP inhibitors, a single dose of <i>l-</i>THP (9 mg/kg) was orally administrated.…”

αNa,K-ATPase levels. by Reem Ismael-Badarneh (3213921)

“…Ang II administration decreased Na,K-ATPase levels by 0.65 folds compared to the control group. * P < 0.001 As compared to control group. …”

Compact Conformations of Human Protein Disulfide Isomerase by Shang Yang (607468)

“…<div><p>Protein disulfide isomerase (PDI) composed of four thioredoxin-like domains <b>a</b>, <b>b</b>, <b>b'</b>, and <b>a'</b>, is a key enzyme catalyzing oxidative protein folding in the endoplasmic reticulum. …”

Disordered Flanks Prevent Peptide Aggregation by Sanne Abeln (268391)

“…The work provides insights into a mechanism that prevents the aggregation of signalling peptides, distinct from the general mechanism of protein folding, and provides a testable hypothesis to explain the abundance of disordered regions in proteins.…”

Wear reconstruction of the teeth of <i>Yindirtemys deflexus</i> (Ctenodactylidae, Rodentia) and evolution of its dental pattern by Adriana Oliver (4803228)

“…<p>The dental pattern of <i>Yindirtemys deflexus</i> from Mongolia has been analysed using a Micro-CT scanner. This ctenodactylid exhibits a peculiar dental pattern, characterised by a mesodont dentition with some degree of selenodonty, an intricate enamel folding and elevated connections between cusps. …”

Poster Scientific Sessions 2019 MDG.pdf by Marco De Giorgi (14580523)

“…Given the important role for N-linked glycosylation in protein folding in the ER, we hypothesized that depletion of dolichol, a scaffold for synthesis of N-linked glycans, could be responsible for the hepatocyte ER stress. …”