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461
New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres
Published 2017“…It increased caspase 3/7 activity by 2.4- and 1.85-fold between 4 and 8 h of treatment, respectively, at 10 μM and it caused a decrease in the percentage of cells in the G1 phase of the cell cycle with a corresponding increase in the S-phase. …”
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Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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477
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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478
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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479
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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480
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”