Showing 581 - 600 results of 35,452 for search '(( 50 ((a decrease) OR (we decrease)) ) OR ( a ((fold decrease) OR (nn decrease)) ))', query time: 0.83s Refine Results
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    DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

    Published 2023
    “…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”
  5. 585

    DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

    Published 2023
    “…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”
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    Predicted targets of miR-337-3p decrease in mRNA expression on over-expression of miR-337-3p. by Liqin Du (158175)

    Published 2012
    “…<p>(A) Expression levels of miR-337-3p after 72 h transfection of NCI-H1155 cells with 50 nM miR-337-3p mimic as measured by qRT-PCR. …”
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    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…Among them, compound <b>LQ23</b> showed more elevated inhibitory activity against CLK2 than the lead compound (IC<sub>50</sub>, 1.4 nM) with high CLK2/CLK3 selectivity (>70-fold). …”
  16. 596

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…Among them, compound <b>LQ23</b> showed more elevated inhibitory activity against CLK2 than the lead compound (IC<sub>50</sub>, 1.4 nM) with high CLK2/CLK3 selectivity (>70-fold). …”
  17. 597

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…Among them, compound <b>LQ23</b> showed more elevated inhibitory activity against CLK2 than the lead compound (IC<sub>50</sub>, 1.4 nM) with high CLK2/CLK3 selectivity (>70-fold). …”
  18. 598

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…Among them, compound <b>LQ23</b> showed more elevated inhibitory activity against CLK2 than the lead compound (IC<sub>50</sub>, 1.4 nM) with high CLK2/CLK3 selectivity (>70-fold). …”
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