Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H₂O₂ and Inflammatory Cytokine Production by Junnan Chen (270183)

“…Proteomic analysis of three in vitro and two in vivo models revealed a decrease in antioxidant proteins that regulate H₂O₂ processing, by ≥2 fold in CF vs. matched normal controls. …”

Fitness reaction norms and experimental evolution design. by Thiago S. Guzella (5920229)

“…Here we genotype individual hermaphrodites at several time points during experimental evolution, at single nucleotide polymorphisms (SNPs) across pairs of chromosomes (vertical dashed lines, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007731#pgen.1007731.g002" target="_blank">Fig 2</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007731#pgen.1007731.g003" target="_blank">Fig 3</a>). …”

Data Sheet 1_Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses.docx by Rafael Bayarri-Olmos (695469)

“…Although MBL binding decreased post-vaccination, it increased by 2.6-fold upon IgG depletion, suggesting a compensatory or redundant role in immune recognition. …”

Comparative genome hybridization of four spontaneous ceftazidime-resistant mutants revealing mutations in gene PA3047. by Bartolomé Moya (265834)

“…In mutant 1A1 and 1D4, a slight decrease in signal (+) pointed towards a small genetic change, e.g., a single point mutation.…”

Effects of DE genes in Fatty Acid Metabolism. by Leonel N. Leal (5598308)

“…<p>Values under gene symbols represent direction expression of DE genes (fold change). Relationship lines in orange indicate that genes showed a directional expression compatible with an increased function. …”

AM are differentially expressed in early hematopoietic and endothelial subpopulations of developing EB. by Basha L. Stankovich (207031)

“…Dashed line represents 2-fold increase/decrease in transcript expression level. …”

Cryptic antisense transcripts in CAF-1 complex mutants. by Harm van Bakel (32951)

“…The set of AS transcripts was compiled by first identifying all AS transcripts with a more than 2-fold change in expression and a p-value<0.05 over at least 80 bp (10 probes) in at least one compendium condition, and then combining these transcripts in a non-redundant union set. …”

Effects of DE genes in Mitosis. by Leonel N. Leal (5598308)

“…<p>Values under gene symbols represent direction expression of DE genes (fold change). Relationship lines in orange indicate that genes showed a directional expression compatible with an increased function. …”

The effect of brain co-culture on the protein expression of skin-derived and glandular stem cells. by Anna E. Petschnik (344262)

“…The percentage of NF-positive cells increased in all populations up to 4-fold, accompanied by the general exhibition of an elongated morphology resembling uni- and bipolar neurons (<b>G–L</b>; arrows). α-SMA-positive cells decreased in number and/or showed a visible degradation of the actin filaments (<b>M–R</b>). …”

Perturbation of <i>Gata1</i> regulatory dynamics impacts frequency of commitment <i>in silico</i> and <i>in vitro</i>. by Jose Teles (5655964)

“…(F) Inspection of clonal culture-reconstitution capacity of transduced EML cells before and after treatment. The 2-fold decrease in large reconstituting colonies between control and GATA1-ERT pulsed cells (red bars) matches the 2-fold gain in commitment predicted in D.…”

Tofu and fish oil independently modulate serum lipid profiles in rats: Analyses of 10 class lipoprotein profiles and the global hepatic transcriptome by Yoko Takahashi (799999)

Data from: Increased Soil Nitrogen Availability Suppresses Annual Soil Respiration in Mixed Temperate Forests Regardless of Acidification by David W. Frey (21072152)

“…Treatments were selected for their abilities to increase (NaNO₃) or decrease ((NH₄)₂SO₄, S) soil pH. …”

Generation of transcriptome datasets. by Paul Montague (285622)

“…The resultant transcriptome database (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009892#pntd.0009892.s007" target="_blank">S2 Table</a>) set out for each pairing in order of decreasing p values and corresponding fold changes.…”

The impact of sample size reduction magnitude on the precision of the estimate of the differential effect of treatment. by Ognjen Arandjelović (295373)

XpYp telomere end distributions in single telomere length analysis (STELA) (6 lanes/sample). by Ulrika Svenson (285527)

Effects of silencing the expression of Rae1 on mRNA expression in VSV-infected cells. by Karishma R. Rajani (131547)

“…Data shown are gene symbols of probe sets that were reproducibly decreased (<b>A</b> and <b>B</b>) or increased (<b>C</b> and <b>D</b>) by greater than 3-fold in VSV-infected versus mock-infected siNT cells (<b>A</b> and <b>C</b>) or siRae1 cells (<b>B</b> and <b>D</b>). …”

LP I_h metamodulation is rapid and reversible. by Wulf-Dieter C. Krenz (693267)

“…The percent change in LP I_h G_max relative to t = 0 is plotted (mean±SEM, increases are positive, decreases are negative). Asterisks indicate significantly different from t = 30min as determined using a repeated measures ANOVA with Dunnett’s post-hoc tests that compared all time points to t = 30min, F(5,5) = 2.677, p = 0.0453.…”

DHEA and DHEA8354 suppress the growth of mammary tumors by Anne Shilkaitis (15502)

“…Growth curves of mammary tumors in animals treated with dehydroepiandrosterone (DHEA) (b) or DHEA 8354 (c) (1,000 mg/kg in diet). In 50% of DHEA-treated tumors a net decrease in growth potential over control was observed, whereas with DHEA 8354 some animals showed a decrease in growth potential. …”

Resisting hostility generated by terror: An agent-based study by Sylvie Huet (130903)

“…An agent forms an attitude about another agent depending on the similarity between their cultural identities. When a terrorist attack is perpetrated in the name of an extreme cultural identity, the negatively perceived agents from this extreme cultural identity point of view tend to decrease the width of their acceptance segments in order to differentiate themselves more from the threatening cultural identity. …”

Antiviral/type I IFN response following TDV vaccination. by Fiona R. Strouts (2805394)

“…Red indicates an increase in transcript abundance; blue indicates decreased transcript abundance (FDR<0.05, fold-change≥1.3). …”