IGFBP-3 activates PI3kinase via scavenger receptor-B1. by Yagna P. R. Jarajapu (316562)

“…PI3K activity was enhanced by up to 7-fold by IGFBP-3, which was significantly decreased by pretreatment with scavenger receptor-B1 neutralizing antibody (SRB1-Ab) (P<0.05, n = 3). …”

Theory of FRET “Spectroscopic Ruler” for Short Distances: Application to Polyproline by Ekaterina Sobakinskaya (4714518)

“…The interpretations of FRET experiments with standard Förster theory relies on the following approximations: (i) a point-dipole approximation (PDA) for the coupling between transition densities of the chromophores, (ii) a screening of this coupling by the inverse optical dielectric constant of the medium, and (iii) the assumption of fast isotropic sampling over the mutual orientations of the chromophores. …”

Theory of FRET “Spectroscopic Ruler” for Short Distances: Application to Polyproline by Ekaterina Sobakinskaya (4714518)

“…The interpretations of FRET experiments with standard Förster theory relies on the following approximations: (i) a point-dipole approximation (PDA) for the coupling between transition densities of the chromophores, (ii) a screening of this coupling by the inverse optical dielectric constant of the medium, and (iii) the assumption of fast isotropic sampling over the mutual orientations of the chromophores. …”

Presentation_1_Influence of acetate- vs. lactate-containing fluid bolus therapy on acid-base status, electrolytes, and plasma lactate in dogs.PPTX by Ute Klein-Richers (13172571)

The simulated effect of intracellular free magnesium ion concentration ([Mg²⁺]_i) on junctional conductance and the spread of excitation through electrical syn... by Mindaugas Snipas (3909556)

“…The spread of APs was not disturbed by voltage-gating induced g_j decrease (see the upper inset in 10B). At [Mg²⁺]_i = 1.0 mM, the steady-state g_j value of ~1 nS was sufficient to transfer each AP initially, but the decreased g_j caused a 2-fold lower firing rate in the postsynaptic cell, as compared with [Mg²⁺]_i = 0.8 mM. …”

Swimming endurance training protocol. by Vítor S. Fernandes (21262991)

“…This study aimed to investigate the effect of <i>MIB1</i> mutations on cardiac electrical activity. We examined male <i>Mib1</i>^<i>flox</i><i>;Tnnt2</i>^<i>Cre</i> mice, a disease model of LVNC, and wildtype littermates on the C57BL/6J genetic background. …”

<i>Yap (5SA)</i> mRNA-injected embryos exhibit dramatic downregulation of retinal photoreceptor genes. by Yoichi Asaoka (564124)

“…<p>(A) The top five GO categories for genes downregulated by over 4.0-fold in <i>yap (5SA)</i>-expressing embryos at 48 hpf as determined by microarray analysis. …”

Effects of administration regimen on antitumor activity, TK activity and viral replication. by Daniel Abate-Daga (200715)

“…GCV treatment produced a significant decrease in the number of ICOVIR5-TK-L transducing units regardless of the protocol applied (A or B) (left panel). …”

Beta Diversity and Differential Abundance Analysis of Gut Microbiota after FVT. by Melany Cervantes-Echeverría (22794116)

“…Differentially abundant taxa were identified using DESeq2 with a p-value < 0.05 and a Log2 fold change (Log2FC) cutoff of 1.5. …”

New Targets for Drug Discovery against Malaria by Guido Santos (171018)

The impact of sample size reduction timing on the precision of the estimate of the differential effect of treatment. by Ognjen Arandjelović (295373)

Real time PCR based mitochondrial DNA copy number determination in oral cancer. by Rosy Mondal (385209)

“…(C) Mitochondrial content decreases with increase in tumour stage: the various stages of OSCC samples from stage 0 to stage IVB with respect to log 2 RQ (log fold change).…”

<i>phox2b</i>, but not <i>ascl1</i>, is indispensable for sympathetic neuronal differentiation. by Desheng Pei (418653)

“…Lateral views depict a minimal decrease in expression of <i>th</i> (A,B) and <i>dbh</i> (D,E) in <i>ascl1</i> MO-injected embryos compared to control MO-injected (A,D) embryos. …”

DataSheet1_PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo.docx by Alexia Chauzy (12247643)

Lanthanide-Containing Metallomesogens with Low Transition Temperatures by Yuetao Yang (2532472)

“…It is shown that the clearing point can be detected by monitoring the luminescence decay time as a function of the temperature.…”

Diploid sexual populations evolve mutational robustness at lower mutation rate. by Kerry J. Kim (266640)

“…<p>Plots show results of 38 simulations to 5,000 generations with μ = 0.005, smoothed with a sliding window of 100 generations. (A) Robustness to point mutations shows diploid sexual populations evolve greater robustness, while diploid asexual populations have a transient decrease in robustness. …”

Lanthanide-Containing Metallomesogens with Low Transition Temperatures by Yuetao Yang (2532472)

“…It is shown that the clearing point can be detected by monitoring the luminescence decay time as a function of the temperature.…”

Lanthanide-Containing Metallomesogens with Low Transition Temperatures by Yuetao Yang (2532472)

“…It is shown that the clearing point can be detected by monitoring the luminescence decay time as a function of the temperature.…”

Stochastic presentation of tumor resistance to apoptosis induction. by Megan Olsen (248910)

“…Only very high rates of failure complying with the rescue protocols within the cancer cells will result in a loss of tissue integrity. We see a sharp decrease in success rates once the protocols reach that high failure level, demonstrating that once the point of protocol break is crossed, any greater break will cause the system to deteriorate even faster.…”

NPC galvanotaxis persists only for as long as the dcEF stimulus is present. by Robart Babona-Pilipos (207657)

“…<p>(<b>A–D</b>) Analysis of cell migration for 20 minutes before and 20 minutes after the removal of the dcEF reveals a significant decrease in dcEF vector displacement (<b>A</b>), velocity (<b>B</b>), and directedness (<b>C</b>) of migration, as well as a significant increase in tortuosity (<b>D</b>). …”