Clinical improvement of juvenile macaques with chronic diarrhea following <i>T. trichiura</i> treatment. by Mara Jana Broadhurst (120227)

“…Fecal consistency scores (FCS) were based on a standardized 4-point scale; 1 = Well-formed, normal; 1.5 = Normal to semi-solid; 2 = Semi-solid to normal; 2.5 = Semi-solid; 3 = Semi-solid to liquid; 3.5 = Liquid to semi-solid; 4 = Liquid. …”

Multiplex serological analysis of <i>T</i>. <i>cruzi</i>-specific antibodies after long-term follow-up of chronic Chagas disease patients treated with benznidazole. by María G. Alvarez (166567)

“…Time 0 indicates the assay point just prior to benznidazole treatment. (*) Indicates a decrease in MFI higher than fifty percent compared with pre-treatment values.…”

COVID-19 AND THE INFLUENCE OF SOCIAL RESTRICTION ON PHYSICAL ACTIVITY AMONG CHILDREN AND ADOLESCENTS by Suedem Andrade Milani (14281871)

“…With the exception of one article, the synthesis of results indicated a decrease in PA levels and an increase in time spent on screen activities during the social restriction period, in greater proportions for adolescents and for females. …”

DAPT treatment enabled further expansion of NPC in P1 aggregates. by Shunsuke Yuri (754861)

“…<p><b>(A)</b> qRT-PCR results from E12.5 aggregates after treatment with either DMSO or DAPT for 7 days show a significant increase in NPC marker genes (<i>Six2</i> and <i>Eya1</i>) and a significant decrease in differentiated MM cell marker genes (<i>Podxl1</i>, <i>Nkcc2</i> and <i>Slc5a1</i>, but not <i>Slc12a3</i>) in DAPT-treated aggregates as compared to DMSO-treated aggregates. …”

DataSheet_1_New-onset metabolic syndrome is associated with accelerated renal function decline partially through elevated uric acid: an epidemiological cohort study.docx by Qiuyu Xu (15343944)

“…</p>Results<p>Of all groups of MetS states, the new-onset MetS showed the most significant eGFR decline, with a 6.66 ± 8.21 mL/min/1.73 m² decrease over 6 years. …”

Data Sheet 1_The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters.pdf by Rajesh Kumar Madhavan (20634731)

“…Lumen impingement, representing one obstruction-based pinch point in the lumen, showed a considerable increase in relative resistance as obstruction diameter increased and lumen diameter at the pinch point decreased (P = 0.001, n = 5). …”

Supplementary file 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.pdf by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Table 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

MicroRNAs differentially expressed in melanocytes of skin after exposure to ssUVR. by Jingfeng Sha (2696932)

“…The color bars at the top of <b>(a)</b> and <b>(b)</b> represent the normalized intensity of down-regulated or up-regulated UV-miRNAs with the shaded blue corresponding to a decrease in expression and that of shaded red to an increase in expression. …”

Confirmation of the effect of methylglyoxal on the expression of selected genes. by Kiyoshi Mori (289003)

“…Administration of 100 µM of MG resulted in a 3.88- and a 4.63-fold increase in sFRP-4 and RANKL mRNA expression, respectively, but a decrease in OPG expression to 10% of its basal level. …”

Table 3_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.csv by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Table 4_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

3D Printing of PDMS Improves Its Mechanical and Cell Adhesion Properties by Veli Ozbolat (4743921)

“…Despite extensive use of polydimethylsiloxane (PDMS) in medical applications, such as lab-on-a-chip or tissue/organ-on-a-chip devices, point-of-care devices, and biological machines, the manufacturing of PDMS devices is limited to soft-lithography and its derivatives, which prohibits the fabrication of geometrically complex shapes. …”

DSS-induced colitis mouse model. by William C. Reisdorf (6616148)

“…Experimental groups were: Sham = vehicle control (no DSS or other treatment, n = 6), DSS = DSS-only (n = 12), CsA = 10 mg/kg i.p. treatment (n = 6), EPHX2i = GSK1910364A 50 mg/kg orally, twice daily (n = 6). …”

Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity by Céline M. Bourdin (446325)

“…PaTEH1B caused a 2.2-fold current density decrease, concomitant with an equivalent α-subunit incorporation decrease in the plasma membrane, compared to PaTEH1A and PaTEH1Δ(270-280). …”

Intense reelin IR neurons synthesize reelin whereas punctate reelin IR neurons are characterized by the presence of receptor-bound reelin. by Cecilia Gonzalez Campo (264260)

“…GST-RAP was used at 25, 40 and 50 µg/ml. A significant decrease of punctate reelin IR was observed with 40 and 50 µg/ml of GST-RAP (4.5±1.5% and 3.1±0.7%; n = 3 and 3) whereas no effect was detected with a concentration of 25 µg/ml compared to untreated (22.2±1.4% and 21.3±2.2%; n = 3 and 3; F_(3,8) = 45.7, ***P<0.001). …”

<i>Vg</i> expression regulates Lp-mediated accumulation of lipids via TOR signaling. by Iryna Stryapunina (17867390)

“…(C) Western blot quantification from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011145#pgen.1011145.g003" target="_blank">Fig 3D</a> showing a decrease in phospho-S6K levels in the fat body upon rapamycin treatment; samples of five tissues, three biological replicates (ANOVA). …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…The topological knot is thought to play a stabilizing role in maintaining the global fold and nature of proteins with the underlying mechanism yet to be elucidated. …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…The topological knot is thought to play a stabilizing role in maintaining the global fold and nature of proteins with the underlying mechanism yet to be elucidated. …”