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point decrease » point increase (Expand Search)
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40801
Image_2_Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma.jpeg
Published 2024“…</p>Results<p>In this study we demonstrate non-invasively, using longitudinal MRI surveillance, the potent antineoplastic effects of GaM in a novel rat xenograft model of trGBM, as evidenced by extended suppression of tumor growth (23.56 mm<sup>3</sup>/week untreated, 5.76 mm<sup>3</sup>/week treated, P < 0.001), a blunting of tumor perfusion, and a significant survival benefit (median overall survival: 30 days untreated, 56 days treated; P < 0.001). …”
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40802
Image_1_Vaginal Dysbiotic Microbiome in Women With No Symptoms of Genital Infections.tif
Published 2022“…L. iners was detected from both the groups with a relative frequency of 50.4% and 17.2% in normal and BV microbiota respectively. …”
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40803
Image_3_Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma.jpeg
Published 2024“…</p>Results<p>In this study we demonstrate non-invasively, using longitudinal MRI surveillance, the potent antineoplastic effects of GaM in a novel rat xenograft model of trGBM, as evidenced by extended suppression of tumor growth (23.56 mm<sup>3</sup>/week untreated, 5.76 mm<sup>3</sup>/week treated, P < 0.001), a blunting of tumor perfusion, and a significant survival benefit (median overall survival: 30 days untreated, 56 days treated; P < 0.001). …”
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40804
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40805
Morphological and quantitative assessment of inguinal mammary glands from 12, 14, and 16 month old WT and VDR KO mice.
Published 2013“…<p>A. (Left Panels) Glands from VDR KO mice show decreased secondary and tertiary branching, signs of ductal thickening (ectasia), and large lymph nodes as the adipose tissue begins to atrophy with age. …”
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40806
Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx
Published 2025“…All patients received external beam radiation therapy (EBRT) with a prescription dose of 50.4 Gy/28f, and daily oART with FBCT guidance was performed. …”
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40807
Variation of PA/DAG ratio modulates the sensitivity and dose response of the pathway.
Published 2020“…<b>(E)</b> The parameter scaling factor refers to the fold-change by which the parameters <i>k</i><sub><i>DAGK</i></sub>, <i>k</i><sub><i>PAP</i></sub>, <i>k</i><sub><i>basal</i>,<i>dp</i></sub>, and <i>K</i><sub><i>PA</i></sub> were decreased, while the parameter <i>k</i><sub><i>off</i>,<i>c</i></sub> was divided by the scaling factor to increase its value. …”
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40808
Identification and verification of differentially expressed key genes in peripheral blood-derived T cells between chronic immune thrombocytopenia patients and healthy controls
Published 2022“…<p>Immune thrombocytopenia (ITP), characterized by decreased platelet counts, is a complex immune-mediated disorder with unelucidated pathogenesis. …”
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40809
Experimental evolution scheme used to evolve yeasts.
Published 2018“…<p><b>A)</b> We used a modified serial dilution transfer method in which yeast and bacteria were co-cultured to compete only during the exponential phase to allow selection at maximum growth rates when resources were unlimited [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194911#pone.0194911.ref046" target="_blank">46</a>] by decreasing with time. …”
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40810
Overexpression of inactive Taspase1 mutants does not inhibit Taspase1’s <i>cis-</i> or <i>trans</i>-cleavage activity.
Published 2012“…Even co-transfection of a nine-fold excess of plasmids encoding the inactive Taspase1 variants did not affect A<b>•</b>M_S2<sub>R</sub> processing in living HeLa cells. …”
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40811
DataSheet1_Simple Autofluorescence-Restrictive Sorting of eGFP+ RPE Cells Allows Reliable Assessment of Targeted Retinal Gene Therapy.pdf
Published 2022“…In our hands the method may provide quantitative and qualitative advances in terms of up to 7-fold enrichment of true eGFP<sup>+</sup> RPE cells compared to a standard protocol. …”
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40812
Presentation_1_Does Impedance Matter When Recording Spikes With Polytrodes?.pdf
Published 2018“…The poly (3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT-PSS) electrodeposition protocol is a simple, stable, and reliable method for decreasing the impedance of a microelectrode up to 10-fold. …”
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40813
Comparisons between simulated and experimental free-running period shifts <i>δτ</i> in different constant light conditions and genetic backgrounds for plant models AP2012 and AP201...
Published 2020“…Hence, <i>δτ</i> < 0 corresponds to a short-period mutant (denoted by a − sign) and <i>δτ</i> > 0 corresponds to a long-period mutant (denoted by a + sign). …”
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40814
Abnormal Changes in NKT Cells, the IGF-1 Axis, and Liver Pathology in an Animal Model of ALS
Published 2011“…Hepatic expression levels of insulin-like growth factor (IGF)-1 decreased, while the expression of IGF binding protein (IGFBP)-1 was augmented by more than 20-fold in mSOD1 mice relative to wild-type animals. …”
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40815
DataSheet1_Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes.PDF
Published 2023“…In CM stimulated with phenylephrine (PE), depletion of Fbxo6, Fbxo25, Fbxo33, Fbxo45, and Fbxw4 further augmented PE-induced hypertrophy. As a proof-of-concept, the CRL<sup>Fbox25</sup> was analysed by transverse aortic constriction (TAC) resulting in a 4.5-fold increase in Fbxo25 protein concentrations compared to control animals. …”
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40816
DNA binding activity of RegX3.
Published 2011“…<p>(A) Phosphorylation of RegX3 by EnvZ. 1 µM EnvZ protein was incubated with <sup>32</sup>P-ATP for 5 min. …”
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40817
Table1_Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes.DOCX
Published 2023“…In CM stimulated with phenylephrine (PE), depletion of Fbxo6, Fbxo25, Fbxo33, Fbxo45, and Fbxw4 further augmented PE-induced hypertrophy. As a proof-of-concept, the CRL<sup>Fbox25</sup> was analysed by transverse aortic constriction (TAC) resulting in a 4.5-fold increase in Fbxo25 protein concentrations compared to control animals. …”
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40818
Inference of Epidemiological Dynamics Based on Simulated Phylogenies Using Birth-Death and Coalescent Models
Published 2014“…In our analyses that estimate the growth rate of an epidemic based on simulated birth-death trees, the point estimates such as the maximum a posteriori/maximum likelihood estimates are not very different. …”
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40819
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40820
PTE reduced fat storage and lipid droplet size.
Published 2015“…<p>(a) Fat storage indicated by Nile Red staining of fixed late L4 N2 worms treated with different concentrations of PTE. …”