Tet2 and Tet3 function upstream of the Notch and Wnt pathways during RGC differentiation and morphogenesis. by Pawat Seritrakul (4445662)

“…(I-L) Wnt signaling was upregulated by exposing wild-type embryos from 24hpf to 72hpf with 2μM BIO, a GSK3β inhibitor. (I,J) BIO-treated wild-type embryos showed reduced lamination, (K) a decreased percentage of <i>isl2b</i>:GFP⁺ RGCs per retina, and (L) decreased optic nerve diameter relative to DMSO-treated controls, (p = 0.00236 and p<0.0001). …”

Effects of adipose-derived stem cells (ASCs) on airway hyperresponsiveness (AHR) and inflammatory cells in the bronchoalveolar lavage fluid (BALF). by Kyu-Sup Cho (770125)

Impacts of rural tourism-driven land use change on ecosystems services provision in Erhai Lake Basin, China by Li, Jinghui

“…The results show that constructed area in ELB, especially in the lakeside zone, increased strongly from 2000 to 2015 due to a tourism boom (in which tourism revenues increased 12-fold), at the expense of farmland, grassland, and forest. …”
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Composite Interval Mapping Based on Lattice Design for Error Control May Increase Power of Quantitative Trait Locus Detection by Jianbo He (2037922)

“…The simulation results showed that the arithmetic mean method, which is equivalent to a method under random complete block design (RCBD), was very sensitive to the size of the block variance and with the increase of block variance, the power of QTL detection decreased from 51.3% to 9.4%. …”

Transcriptome, Methylome and Genomic Variations Analysis of Ectopic Thyroid Glands by Rasha Abu-Khudir (239643)

“…<div><h3>Background</h3><p>Congenital hypothyroidism from thyroid dysgenesis (CHTD) is predominantly a sporadic disease characterized by defects in the differentiation, migration or growth of thyroid tissue. …”

Analysis of 2'-O-ribose methylation in <i>S</i>. <i>cerevisiae</i> exposed to hydrogen peroxide. by Lauren Endres (765718)

“…Fold changes represent increases or decreases in AvP values relative to wt untreated cells and were calculated using the AvP values from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229103#pone.0229103.s003" target="_blank">S1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0229103#pone.0229103.s004" target="_blank">S2</a> Tables, with error bars indicating the standard error of the mean change (n = 3).…”

Data_Sheet_1_Effects of Biotin-Avidin Interactions on Hydrogel Swelling.PDF by Talaial B. Alina (9659489)

“…The objective of this study was to evaluate the effect of increasing biotin and avidin concentrations on hydrogel swelling properties, as an indicator of crosslinking. Gelatin, selected as a model hydrogel material, was biotinylated at increasing fold molar excesses of biotin with a PEG linker using N-hydroxysuccinimide chemistry. …”

Determinants of Sensitivity to DZNep Induced Apoptosis in Multiple Myeloma Cells by Zhigang Xie (203103)

“…<div><p>The 3-Deazaneplanocin A (DZNep), one of S-adenosylhomocysteine (AdoHcy) hydrolase inhibitors, has shown antitumor activities in a broad range of solid tumors and acute myeloid leukemia. …”

Table_1_Improving T-DNA Transfer to Tamarix hispida by Adding Chemical Compounds During Agrobacterium tumefaciens Culture.docx by Huimin Zhao (9433532)

“…DTT treatment decreased reactive oxygen species accumulation. AS treatment activated the expression of the genes virA, virB1, virC1, virD1, virD2, virD4 and virG. …”

Dissecting Rice Polyamine Metabolism under Controlled Long-Term Drought Stress by Phuc Thi Do (400638)

“…<div><p>A selection of 21 rice cultivars (<i>Oryza sativa</i> L. ssp. …”

Quantitative comparison of differentially expressed transcripts and the biological responses that are significantly enriched in mast cells by AgNPs. by Monica Johnson (4993490)

“…Significance was set at <i>p</i>≤0.05 with a fold enrichment cutoff of ≥5. RTK, receptor tyrosine kinase; MAPK, mitogen-activated protein kinase.…”

Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer by Mohd. Altaf Najar (10586881)

“…Treatment of gastric cancer cell lines with a CAMKK2 inhibitor, STO-609, resulted in decreased cell migration, invasion, and colony-forming ability and a G1/S-phase arrest. …”

DataSheet_1_Key Role of Staphylococcal Fibronectin-Binding Proteins During the Initial Stage of Staphylococcus aureus Keratitis in Humans.pdf by Corantin Maurin (9155070)

“…The deletion of staphylococcal fnbA/B genes decreased by 71% the adhesion level to immobilized fibronectin (p < 0.001). …”

The Phosphoarginine Energy-Buffering System of <i>Trypanosoma brucei</i> Involves Multiple Arginine Kinase Isoforms with Different Subcellular Locations by Frank Voncken (101666)

“…Northern blot analysis indicated that each TbAK isoform is differentially expressed in bloodstream and procyclic forms of <i>T. brucei</i>, while the total cellular arginine kinase activity was 3-fold higher in bloodstream form trypanosomes. These results suggest a substantial change in the temporal and spatial energy requirements during parasite differentiation. …”

Influence of pressure on VIP concentration within the chick choroid by Evgeny Privalov (13769986)

“…(III) Chr-VIP elevation at higher atmospheric pressure ranged between 1.37 (24 h) and 1.54-fold (72h).</p> <p><strong>Conclusions</strong>: Increased chr-VIP concentration argues for a decreased chr-VIP release. …”

DataSheet_1_Transcriptomic analysis of pea plant responses to chitooligosaccharides’ treatment revealed stimulation of mitogen-activated protein kinase cascade.zip by Polina Yu. Kozyulina (14758609)

“…We observed 886 differentially expressed genes (fold change ≥ 1; p-value < 0.05) 24 h after treatment with CO8-DA. …”

Serum Proteome Profiling Identifies Novel and Powerful Markers of Cystic Fibrosis Liver Disease by Timo Rath (389419)

“…At a cut-off value of 6.3 kPa, transient elastography compassed a very high diagnostic accuracy and specificity for the detection of CFLD. …”

Gene expression changes in ocular tissues between WT and <i>CFB ^−/−</i> mice following CE. by Alex Woodell (426394)

“…Quantitative values were obtained by cycle number (<i>C</i>t value), determining the difference between the mean experimental and control (Actb) Δ<i>C</i>t values for cigarette smoke (CE) versus room-air-exposed mice within each genotype (fold difference). Candidates were examined from a number of categories including photoreceptor cell function (Rho, Opn1sw, Opn1mw, Rpe65), complement activation (C3, Cfb, Cfd, Cfh, Cd55, Cd59a), control of angiogenesis (Vegfa, Serpinf1), oxidative stress (Hif1a, Cp), autophagy (Lyz1, Lamp2, Klc3), and mitochondrial function (Mfn1, mt-Co1, Dnm1l, Ndufb8, Pfkfb1, Hmox1). …”

Trends in spatial patterns of heavy metal deposition on national park service lands along the Red Dog Mine haul road, Alaska, 2001–2006 by Peter N. Neitlich (4034300)

“…Posterior predictions were simulated 200 times both on a coarse grid of 2,357 points and by distance-based strata including subsets of these points. …”

The effect of HA digestion and HA replenishment alone or with CS on barrier function measured by TEER. by Charlotte J. van Ginkel (20790466)

“…In (B) and (C) each point represents a mean ± standard deviation. (B) Hyaluronidase treatment (n = 8) gradually increased TEER, this significantly differed from the untreated group (n = 8) and the PS treated group (n = 8) (p < 0,001). …”