Influence of OTUB1 on IAV transcription and RNA replication. by Yu-Jyun Li (18700176)

Reduced microbiome alpha diversity in young patients with ADHD by Alexander Prehn-Kristensen (262650)

“…In detail, the bacterial family <i>Prevotellacae</i> was associated with controls, while patients with ADHD showed elevated levels of <i>Bacteroidaceae</i>, and both <i>Neisseriaceae</i> and <i>Neisseria spec</i>. were found as possible biomarkers for juvenile ADHD. Our results point to a possible link of certain microbiota with ADHD, with <i>Neisseria spec</i>. being a very promising ADHD-associated candidate. …”

Contributing mechanisms of immunodominance. by Eung-Jun Im (79648)

“…C) The response kinetics of CD8⁺ T cells re-stimulated with 0.1 µM peptides was assessed in an ICS assay in 1-h intervals for a period of 4 h. Data shown are as mean±SD of [CD8⁺CD107a/b⁺IFN-γ⁺ cells at each time point (%)] ÷ [CD8⁺CD107a/b⁺IFN-γ⁺ at 4 h (%)]. …”

Robustness of the segmentation algorithm. by N. Ezgi Wood (6519662)

“…The algorithm fully recovers the cell in two time points. Note that the algorithm segments the cells backwards in time, thus time points (i.e. frame numbers) are decreasing. …”

Datasheet1_An early predictive model for Kawasaki disease shock syndrome in children in central China.zip by Yali Wu (662911)

“…Indicators of differences were analyzed based on univariate analysis; binary logistic regression analysis was used to identify the risk factors for KDSS, and then receiver operating characteristic analysis was performed to establish a predictive score model for KDSS.</p>Results<p>Elevated neutrophil-to-lymphocyte ratio(NLR) and decreased fibrinogen (FIB) and Na were independent risk factors for KDSS; the scoring of the above risk factors according to the odds ratio value eventually led to the establishment of a new scoring system: NLR ≥ 7.99 (6 points), FIB ≤ 5.415 g/L (1 point), Na ≤ 133.05 mmol/L (3 points), and a total score of ≥3.5 points were high-risk factors for progression to KDSS; otherwise, they were considered to be low-risk factors.…”

Biosynthesis and Thermal Properties of PHBV Produced from Levulinic Acid by <i>Ralstonia eutropha</i> by Yuanpeng Wang (122052)

“…The melting point of PHBV found to be decreased as the fraction of HV present in the polymer increased, which resulted in an improvement in the ductility and flexibility of the polymer. …”

Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism by Vitaly V. Ganusov (142019)

“…<div><p>The kinetics of recirculation of naive lymphocytes in the body has important implications for the speed at which local infections are detected and controlled by immune responses. With a help of a novel mathematical model, we analyze experimental data on migration of ⁵¹Cr-labeled thoracic duct lymphocytes (TDLs) via major lymphoid and nonlymphoid tissues of rats in the absence of systemic antigenic stimulation. …”

Peptidylarginine deiminase inhibition prevents diabetes development in NOD mice by Ada Admin (8524211)

“…Our results point to a role of citrullination in the pathogenesis of autoimmune diabetes, with PAD inhibition leading to disease prevention through modulation of immune pathways. …”

Covariance of shape fluctuations and eigenworms. by Greg J. Stephens (44424)

“…<p>(A) The covariance matrix of fluctuations in angle <i>C</i>(<i>s</i>, <i>s</i>′). …”

Poster ATVB2022 MDG.pptx by Marco De Giorgi (14580523)

“…Dehydrodolichyl diphosphate synthase subunit (DHDDS) is a branch point enzyme that - in complex with Nogo-B receptor (NgBR) - catalyzes the first committed step of dolichol biosynthesis. …”

Flowchart style diagram of methods to sex GD 16.5 to GD 18.0 mice using the external genitalia. by Laura B. Murdaugh (5059100)

“…Minor alterations to consider depending on the age of the fetus in question: 1) at GD 16.5 the dot related to the urethral plate (UP) may still be visible in some males, as the urethra is in the process of internalizing and so step 4 is not sex-specific; 2) after GD 17.5 the dot of step 4 is replaced with a slight opening, as seen in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194767#pone.0194767.g002" target="_blank">Fig 2</a> (GD 18.0 Female) which is sex-specific; 3) at GD 18.0 the preputial growth as occurred in males and females to the point that for steps 2 and 3 to be effective the glans must be positioned at least 3/4s of the way up the overall shape (as seen in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194767#pone.0194767.g002" target="_blank">Fig 2</a> GD 18.0 Male and Female). …”

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…Background<p>High-grade serous carcinoma is a highly metastatic disease with a limited longterm disease control from systemic anti-cancer treatment, for which the radiological treatment response assessment metrics are imprecise. …”

Structure-function relationship in the genotype networks, mapping the centrality of profiles (x-axis) and their average cluster prevalence (y-axis). by Oliver M. Cliff (9585550)

“…The colour shows the genetic distance of a profile to the reference profile (in orange, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008401#pcbi.1008401.g002" target="_blank">Fig 2</a>), with grey points indicating disconnected profiles. …”

Ensemble-Based Computational Approach Discriminates Functional Activity of p53 Cancer and Rescue Mutants by Özlem Demir (199896)

“…Interpreting the number of clusters as a measure of protein flexibility: (i) p53 cancer mutants were more flexible than wild-type protein, (ii) second-site rescue mutations decreased the flexibility of cancer mutants, and (iii) negative controls of non-rescue second-site mutants did not. …”

Structural analysis of transcribed tRNAs by limited nuclease digestion by Myriam Möllers (11061)

“…<p><b>Copyright information:</b></p><p>Taken from "A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNA caused by T7512C and G7497A point mutations"</p><p>Nucleic Acids Research 2005;33(17):5647-5658.…”

Disruption of Transporters Affiliated with Enantio-Pyochelin Biosynthesis Gene Cluster of <i>Pseudomonas protegens</i> Pf-5 Has Pleiotropic Effects by Chee Kent Lim (153180)

“…In contrast, the deletion mutant of PFL_3504 resulted in reduced transcription of the biosynthetic genes as well as decreased dihydroaeruginoic acid concentrations in the culture supernatant, which could either point to regulation of gene expression by the transporter or its role in dihydroaeruginoic acid transport. …”

Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics by Angela M. Boutté (210201)

“…Not only does this study provide a starting point to identify potential biomarkers of metastasis expressed by MDSCs; it identifies critical pathways that are unique to non-metastatic and metastatic conditions. …”

Backward propagating wave and its effect on the physical properties measured. by Assaf Zaritsky (137666)

“…Regardless of the property measured, a spatial pulse-like profile was observed. For example, for a specific time point t (blue) cells near the wound edge do not accelerate, the pulse is maximized for deeper cells and then decreases for cell located farther from the wound edge. …”

Data Sheet 1_Insulin resistance assessed by estimated glucose disposal rate is associated with all-cause and cardiovascular mortality among postmenopausal women.docx by Han Qian (6063431)

“…In comparison to the lowest eGDR quartile, the highest quartile showed adjusted hazard ratios of 0.765 (0.646-0.906) for all-cause mortality and 0.677 (0.498-0.921) for cardiovascular mortality. A U-shaped relationship between eGDR and all-cause mortality was identified, with an inflection point at 5.11 mg/kg/min. …”

Supplemental file for Training alters cytokine and soluble receptor responses by Jeremy Ducharme (20174820)

“…Following 1-hour of cycling at their respiratory compensation point, untrained men (n=5) exhibited a significant increase in pro-inflammatory cytokines, including IL-6, TNF-α, IL-1β, CCL2, and VEGFA. …”