Compound heterozygotes show age-dependent phenotypes. by Anne K. Hennig (78171)

“…Morphologic abnormalities in <i>Cbp CH</i> retinas (panel J) have resolved, although whorls and rosettes are still seen in <i>R-DCKO</i> retinas (panel K). Scale bar  = 50 μm. <b>L</b>–<b>N.</b> ERG testing at 12 weeks revealed decreases in function in both <i>Cbp CH</i> and <i>P300 CH</i>, and <i>R-DCKO</i> retinas have lost cone responses in addition to rod function. …”

Presentation_3_Cytosolic Glutamine Synthetase GS1;3 Is Involved in Rice Grain Ripening and Germination.PDF by Takayuki Fujita (324224)

Data_Sheet_1_Abnormal Dynamic Functional Connectivity in Patients With End-Stage Renal Disease.docx by Xuekun Li (216267)

“…Compared with HCs, both patient groups spent longer time in State 3, in which decreased FC between subnetworks of the default mode network (DMN) and between the dorsal DMN and language network was observed in these patients, and a further reduction in FC between the DMN subnetworks was found in HD patients compared to non-dialysis patients. …”

Chemotherapeutic Sensitization of Leptomycin B Resistant Lung Cancer Cells by Pretreatment with Doxorubicin by Chuanwen Lu (159114)

“…Among the different treatment regimens, pretreatment with DOX (pre-DOX) and subsequent treatment with LMB to A549 cells significantly decreased the 50% inhibitory concentration (IC50) as compared to that of LMB alone (4.4 nM <em>vs.…”

TU-100 (Daikenchuto) and Ginger Ameliorate Anti-CD3 Antibody Induced T Cell-Mediated Murine Enteritis: Microbe-Independent Effects Involving Akt and NF-κB Suppression by Nobuhiro Ueno (346397)

Resistance to <i>Bacillus thuringiensis</i> Mediated by an ABC Transporter Mutation Increases Susceptibility to Toxins from Other Bacteria in an Invasive Insect by Yutao Xiao (725741)

“…The results imply that negative cross-resistance occurs because the wild type ABCC2 protein plays a key role in conferring susceptibility to Cry1Ac and in decreasing susceptibility to abamectin. …”

Glucocorticoid signaling affects chromatin accessibility in pancreatic islets. by Anthony Aylward (10798588)

“…<p>(A) Principal components plot showing ATAC-seq signal for high-dose (red) and low-dose (blue) glucocorticoid-treated islets and untreated (grey) islets from 9 total donors. …”

Image_1_Characterizing the Effect of the Lysine Deacetylation Modification on Enzyme Activity of Pyruvate Kinase I and Pathogenicity of Vibrio alginolyticus.PNG by Zhou Xu (1753744)

“…The ΔpykF mutant exhibited a 6-fold reduction in virulence to zebrafish. Site-directed mutations of K52R and K68R also showed reduced virulence while mutations of K317R didn't. …”

Table_1_Characterizing the Effect of the Lysine Deacetylation Modification on Enzyme Activity of Pyruvate Kinase I and Pathogenicity of Vibrio alginolyticu.docx by Zhou Xu (1753744)

“…The ΔpykF mutant exhibited a 6-fold reduction in virulence to zebrafish. Site-directed mutations of K52R and K68R also showed reduced virulence while mutations of K317R didn't. …”

Poor In Utero Growth and Reduced β-Cell Compensation and High Fasting Glucose from Childhood Are Harbingers of Glucose Intolerance in Young Indians by Chittaranjan S Yajnik (11420147)

“…Participants in the highest quintile of fasting glucose at 6 and 12 years had a 2.5- and 4.0-fold higher risk respectively of 18-year glucose intolerance; this finding was replicated in two other cohorts. …”

Table_1_Characterizing the Effect of the Lysine Deacetylation Modification on Enzyme Activity of Pyruvate Kinase I and Pathogenicity of Vibrio alginolyticus.docx by Zhou Xu (1753744)

“…The ΔpykF mutant exhibited a 6-fold reduction in virulence to zebrafish. Site-directed mutations of K52R and K68R also showed reduced virulence while mutations of K317R didn't. …”

MAS receptor present on adult human cardiac fibroblast primary cells induces CTGF and collagen expression in response to its agonist. by Arunachal Chatterjee (816082)

“…<b>(C)</b> Bar graphs showing real-time PCR analysis of different collagen sub-types (Col1A2 and Col3A1) [represented as fold increase (2^‒ΔΔCt)] in HCF cells. …”

Image_1_Characterizing the Effect of the Lysine Deacetylation Modification on Enzyme Activity of Pyruvate Kinase I and Pathogenicity of Vibrio alginolyticu.PNG by Zhou Xu (1753744)

“…The ΔpykF mutant exhibited a 6-fold reduction in virulence to zebrafish. Site-directed mutations of K52R and K68R also showed reduced virulence while mutations of K317R didn't. …”

HIV-1 Diversity, Transmission Dynamics and Primary Drug Resistance in Angola by Inês Bártolo (232611)

“…The prevalence of subtype A decreased significantly from 2001 to 2009 (40.0% to 10.8%, P = 0.0019) while the prevalence of unique recombinant forms (URFs) increased>2-fold (40.0% to 83.1%, P<0.0001). …”

Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread by Masfique Mehedi (473329)

“…Consistent with reduced spread, there was a 10-fold reduction in the release of infectious progeny virions in ARP2-depleted cells at 72 hr post-infection. …”

Prediction of all-cause mortality after liver transplantation using left ventricular systolic and diastolic function assessment by Young-Jin Moon (2696887)

“…In LVDF analysis, patients with an E/A ratio<0.9(Q1) had a 2.19-fold higher risk of death (95% confidence interval = 1.11–4.32, <i>P</i> = 0.024) than those with an E/A ratio>1.4(Q4). …”

rystal structure and conservation of the Tae4 effector from <i>S. typhimurium</i>. by Juliane Benz (154207)

“…Sc1</i> (ZP_09929551.1) going from dark green (identical residues) to light green, orange and yellow (with decreasing conservation). α-helices and β-strands are colored in orange and green according to (A). …”

Network analysis in the HCM heart compared to the healthy heart. by Jessica Joshua (14803940)

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…WB results also revealed that Andro (5, 20, and 50 μM) reduced p62 expression, while Beclin-1 expression and the LC3A/B-II/LC3A/B-I ratio increased in SW1353 and Hs 819.T cells. …”

Temporal Trends of Transcatheter Edge-to-Edge Repair of the Mitral Valve Short-Term Outcomes in the United States: Nationwide Representative Study by Omar M. Abdelfattah (9601512)

“…</p> <p><b>Results</b>: A total of 22,914 patients underwent TEER; 1,674 in 2014, 3,252 in 2015, 4,645 in 2016, 6,000 in 2017, and 7,343 in 2018 with a median age of 78, 80, 81, and 80 years, respectively, with a 4.2 fold increase in TEER utilization. …”