Microbiota-related metabolites and the risk of type 2 diabetes by Jagadish Vangipurapu (428170)

Image_3_Transgenic tobacco plant overexpressing ginkgo dihydroflavonol 4-reductase gene GbDFR6 exhibits multiple developmental defects.tif by Jun Ni (68173)

“…<p>Dihydroflavonol Q 4-reductase (DFR), a key enzyme in the flavonoid biosynthetic pathway in plants, significantly influences plant survival. …”

Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells by Alexandra M. Fajardo (3176451)

“…TQ pretreatment was also found to inhibit AR activation as measured using the Multifunctional Androgen Receptor Screening assay. Furthermore, TQ decreased androgen-responsive gene expression, including TM4SF1, KLK2, and PSA over 5-fold, whereas AT did not affect the expression of androgen-responsive genes. …”

Table_2_Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women.PDF by Karol Gliniewicz (3538301)

“…The vaginal communities of most postmenopausal women receiving HT (10/15) were dominated by species of lactobacilli and belonged to clusters A, C, and F (P < 0.001). This sharply contrasts with vaginal communities of postmenopausal women without HT, most of which (10/15) were in cluster D, depleted of lactobacilli, and had about 10-fold fewer total bacteria (P < 0.05). …”

Herbivore-induced defence response in the brown seaweed <i>Fucus vesiculosus</i> (Phaeophyceae): temporal pattern and gene expression by Markus Molis (220755)

“…Microarray hybridizations investigating the expression of genes 3 days before, as well as at the same time as, feeding assays revealed a decreased palatability of previously grazed <i>F. vesiculosus</i> pieces compared with non-grazed control pieces. …”

Profound sensitivity of the liver to the direct effect of insulin allows peripheral insulin delivery to normalize hepatic but not muscle glucose uptake in the healthy dog by Guillaume Kraft (10326838)

“…<p>Endogenous insulin secretion is a key regulator of postprandial hepatic glucose metabolism, but this process is dysregulated in diabetes. …”

<i>ISG15</i> expression and protein ISGylation are induced during <i>in vivo</i> erythroid differentiation. by Ana Leticia Maragno (342131)

“…Quantification was performed as described in Mat & Met. Note the two-fold decreased expression of a second housekeeping gene, ß-actin during differentiation. au = arbitrary unit. …”

Blocked NF-κB activation inhibits cytokine-upregulated IgSF molecules expression, and MSC modulates cytokine-induced NF-κB nuclear translocation. by Li Wen (169316)

“…<p>A to C shows FCM analysis of HCE-T cells treated with BMS-345541 (5 µM), a NF-κB pathway inhibitor, significantly inhibited IFN-γ (100 U/ml) and TNF (100 U/ml) induced ICAM-1 (A), HLA-ABC (B), and HLA-DR (C) expression. …”

Image_2_Transgenic tobacco plant overexpressing ginkgo dihydroflavonol 4-reductase gene GbDFR6 exhibits multiple developmental defects.tif by Jun Ni (68173)

“…<p>Dihydroflavonol Q 4-reductase (DFR), a key enzyme in the flavonoid biosynthetic pathway in plants, significantly influences plant survival. …”

DataSheet_1_Microbial respiration in contrasting ocean provinces via high-frequency optode assays.pdf by Melanie R. Cohn (18767155)

“…At the North Atlantic Porcupine Abyssal Plain, surface whole water microbial respiration was higher (1.7 µmol O₂ L^-1 d^-1) than in the Pacific and decreased by 3-fold below the euphotic zone. The Atlantic size-fraction contributions to total respiration shifted on the order of days during the evolution of a phytoplankton bloom with regular storm disturbances. …”

Data_Sheet_1_Implications of specific lysine residues within ataxin-3 for the molecular pathogenesis of Machado-Joseph disease.pdf by Priscila Pereira Sena (15649892)

“…We confirmed earlier findings that levels of lysine-free ataxin-3 are reduced due to its decreased stability, which led to a diminished load of SDS-insoluble species of its polyglutamine-expanded form. …”

Table_1_Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice.docx by Ana C. Marques (149564)

“…We observed that pravastatin induced higher H₂O₂ production rate (40%), decreased activity of aconitase (28%), a superoxide-sensitive Krebs cycle enzyme, and increased susceptibility to Ca²⁺-induced MPT (32%) in liver mitochondria. …”

Table_7_Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women.PDF by Karol Gliniewicz (3538301)

“…The vaginal communities of most postmenopausal women receiving HT (10/15) were dominated by species of lactobacilli and belonged to clusters A, C, and F (P < 0.001). This sharply contrasts with vaginal communities of postmenopausal women without HT, most of which (10/15) were in cluster D, depleted of lactobacilli, and had about 10-fold fewer total bacteria (P < 0.05). …”

Image_2_Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice.JPEG by Ana C. Marques (149564)

“…We observed that pravastatin induced higher H₂O₂ production rate (40%), decreased activity of aconitase (28%), a superoxide-sensitive Krebs cycle enzyme, and increased susceptibility to Ca²⁺-induced MPT (32%) in liver mitochondria. …”

Table_1_Transgenic tobacco plant overexpressing ginkgo dihydroflavonol 4-reductase gene GbDFR6 exhibits multiple developmental defects.xlsx by Jun Ni (68173)

“…<p>Dihydroflavonol Q 4-reductase (DFR), a key enzyme in the flavonoid biosynthetic pathway in plants, significantly influences plant survival. …”

Table_6_Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women.PDF by Karol Gliniewicz (3538301)

“…The vaginal communities of most postmenopausal women receiving HT (10/15) were dominated by species of lactobacilli and belonged to clusters A, C, and F (P < 0.001). This sharply contrasts with vaginal communities of postmenopausal women without HT, most of which (10/15) were in cluster D, depleted of lactobacilli, and had about 10-fold fewer total bacteria (P < 0.05). …”

Table_3_Comparison of the Vaginal Microbiomes of Premenopausal and Postmenopausal Women.pdf by Karol Gliniewicz (3538301)

“…The vaginal communities of most postmenopausal women receiving HT (10/15) were dominated by species of lactobacilli and belonged to clusters A, C, and F (P < 0.001). This sharply contrasts with vaginal communities of postmenopausal women without HT, most of which (10/15) were in cluster D, depleted of lactobacilli, and had about 10-fold fewer total bacteria (P < 0.05). …”

Model-Driven Redox Pathway Manipulation for Improved Isobutanol Production in <i>Bacillus subtilis</i> Complemented with Experimental Validation and Metabolic Profiling Analysis by Haishan Qi (547562)

“…As expected, NADPH pool size in BSUL07 was 4.4-fold higher than that in parental strain BSUL05. …”

DataSheet_1_Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice.pdf by Qixia Shen (11170275)

“…Both B cells and neutrophils decreased by about 3 folds. On the contrary, the proportion of macrophages and dendritic cells (DCs) increased significantly, especially by about a 4.5-fold increase in Ly6c^loMrc1⁺ macrophages and 2.6 folds increase in Ly6c^loEar2⁺ macrophages. …”

Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease by Priyanka S. Sagar (6169736)

“…Increasing water intake reduces renal cyst growth in the <i>pck</i> rat (a genetic ortholog of autosomal recessive PKD) but it is not clear if this beneficial effect is present in other models of PKD. …”