Image_1_Characterizing the Effect of the Lysine Deacetylation Modification on Enzyme Activity of Pyruvate Kinase I and Pathogenicity of Vibrio alginolyticu.PNG by Zhou Xu (1753744)

“…The ΔpykF mutant exhibited a 6-fold reduction in virulence to zebrafish. Site-directed mutations of K52R and K68R also showed reduced virulence while mutations of K317R didn't. …”

HIV-1 Diversity, Transmission Dynamics and Primary Drug Resistance in Angola by Inês Bártolo (232611)

“…The prevalence of subtype A decreased significantly from 2001 to 2009 (40.0% to 10.8%, P = 0.0019) while the prevalence of unique recombinant forms (URFs) increased>2-fold (40.0% to 83.1%, P<0.0001). …”

Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread by Masfique Mehedi (473329)

“…Consistent with reduced spread, there was a 10-fold reduction in the release of infectious progeny virions in ARP2-depleted cells at 72 hr post-infection. …”

Prediction of all-cause mortality after liver transplantation using left ventricular systolic and diastolic function assessment by Young-Jin Moon (2696887)

“…In LVDF analysis, patients with an E/A ratio<0.9(Q1) had a 2.19-fold higher risk of death (95% confidence interval = 1.11–4.32, <i>P</i> = 0.024) than those with an E/A ratio>1.4(Q4). …”

rystal structure and conservation of the Tae4 effector from <i>S. typhimurium</i>. by Juliane Benz (154207)

“…Sc1</i> (ZP_09929551.1) going from dark green (identical residues) to light green, orange and yellow (with decreasing conservation). α-helices and β-strands are colored in orange and green according to (A). …”

The impact of insecticide applications on the dynamics of resistance: The case of four <i>Aedes aegypti</i> populations from different Brazilian regions by Gabriela de Azambuja Garcia (2900918)

“…Temephos resistance was detected in all populations although exhibiting a slight decrease over time probably due to the interruption of field use. …”

Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets by Gregory J. Hogan (160970)

“…<div><p>Reprogramming of a gene’s expression pattern by acquisition and loss of sequences recognized by specific regulatory RNA binding proteins may be a major mechanism in the evolution of biological regulatory programs. …”

Effects of acute Theiler’s murine encephalomyelitis virus (TMEV)-infection (<i>experiment I</i>) upon cytokine expression and phenotypical changes in spleens of interleukin-10 rece... by Ann-Kathrin Uhde (3110976)

“…(J) Flow cytometry revealed a relative increase of CD19⁺ B cells and a simultaneous decrease of CD4⁺ T cells (K) in the spleen of infected mice following IL-10R blockade at 14 dpi. …”

Impact of the Motion Picture (MP) mode of the NEC 24WMGX monitor on visible motion blur. by Tobias Elze (137167)

“…With the MP mode set to its strongest level (b), the visible motion blur had decreased by about 50% on average.</p>…”

Warming up for athletic events by Hussain, Helmi

“…If the results of the research in our field seem to be controversial at this time, that probably is due to the fact that each study has tried to find the answer to the question from a different point of view with different factors involved (24).…”
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DataSheet1_Low-Order Scaling Quasiparticle Self-Consistent GW for Molecules.pdf by Arno Förster (11381271)

“…We demonstrate the computational efficiency of the new implementation by calculating the quasiparticle spectrum of a DNA oligomer with 1,220 electrons using a basis of 6,300 atomic orbitals in less than 4 days on a single compute node with 16 cores. …”

Image_4_Duplex droplet digital PCR detection of Streptococcus uberis and Streptococcus dysgalactiae, major etiological agents of bovine mastitis.pdf by Leticia Diana (472099)

“…Indeed the detection limit for cultures and mock samples for dddPCR was a hundred times lower than the endpoint PCR. Additionally, the CFU/mL estimated based on the number of copies/uL obtained through dddPCR exhibited a strong correlation with the observed CFU/mL from the culture (r^2 > 0.99, p-value < 0.001), indicating that dddPCR provides a dependable estimate of this parameter. …”

Image_1_Duplex droplet digital PCR detection of Streptococcus uberis and Streptococcus dysgalactiae, major etiological agents of bovine mastitis.pdf by Leticia Diana (472099)

“…Indeed the detection limit for cultures and mock samples for dddPCR was a hundred times lower than the endpoint PCR. Additionally, the CFU/mL estimated based on the number of copies/uL obtained through dddPCR exhibited a strong correlation with the observed CFU/mL from the culture (r^2 > 0.99, p-value < 0.001), indicating that dddPCR provides a dependable estimate of this parameter. …”

Analysis of the wavelengths of the colony surface patterns. by Lin Chen (54305)

“…Each dot <i>(C, D)</i> represented a colony from a replicate and a time point. <i>(D)</i> The percent of significant points (Fourier spectral peak height>1.5) plotted as a function of agar. …”

Image_2_Duplex droplet digital PCR detection of Streptococcus uberis and Streptococcus dysgalactiae, major etiological agents of bovine mastitis.pdf by Leticia Diana (472099)

“…Indeed the detection limit for cultures and mock samples for dddPCR was a hundred times lower than the endpoint PCR. Additionally, the CFU/mL estimated based on the number of copies/uL obtained through dddPCR exhibited a strong correlation with the observed CFU/mL from the culture (r^2 > 0.99, p-value < 0.001), indicating that dddPCR provides a dependable estimate of this parameter. …”

Time course of expression and phosphorylation of different proteins involved in intracellullar Ca²⁺ handling. by Jesica S. Rodriguez (556541)

“…Phosphorylation of PLN and RyR2 was expressed as ratio between phosphorylated and non-phosphorylated forms of the proteins. While SERCA2a expression showed no differences at any time point studied, the expression of NCX was significantly higher only in SHRF. …”

<em>In vivo</em> Expansion of Naïve CD4⁺CD25^high FOXP3⁺ Regulatory T Cells in Patients with Colorectal Carcinoma after IL-2 Administration by Marc Beyer (133304)

“…This finding could be confirmed in naïve murine T_reg cells after IL-2 administration. These results point to a more complex regulation of T_reg cells in context of IL-2 administration. …”

Retrospective Analysis for Genetic Improvement of Hip Joints of Cohort Labrador Retrievers in the United States: 1970–2007 by Yali Hou (252579)

“…The OFA hip score is based on a 7-point scale with the best ranked as 1 (excellent) and the worst hip dysplasia as 7. …”

Isothermal efficiency curve for molecular machines showing bounds that constrain the coding space dimensionality <i>D</i>. by Thomas D. Schneider (7610045)

“…These factors lead to an ‘optimal’ molecular machine in which <i>ρ</i> = 1 and <i>ϵ</i>_<i>r</i> = <i>ϵ</i>_<i>t</i> = ln 2. At that point the dimensionality has been squeezed in a pincers (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0222419#pone.0222419.e029" target="_blank">Eq (21)</a>) until it reaches <i>D</i> = 2<i>R</i>.…”

Akt isoforms levels change during neuron development. by Hector Diez (172600)

“…In hippocampal neurons, Akt1 levels decreased from 6 DIV on, Akt2 showed a tendency to reduction from 4 DIV on (which is statistically significant at 4 DIV and 6 DIV) an Akt3 is slightly increased at 2–4 DIV. …”