Image1_Dexmedetomidine Protects Against Septic Liver Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT1 Signaling Pathway.TIF by Qing Yu (337275)

“…</p><p>Conclusion: We demonstrated a novel mechanism in which DEX protects against CLP-induced liver injury. …”

Expression of STAT6 is reduced during KSHV reactivation and early infection. by Feng Gu (45619)

“…(<b>C</b>) Doxycycloline (Dox)-induced RTA expression in iSLK-RTA or iSLK-219 cells led to the decreased expression of STAT6 but not of STAT3. Whole cell lysates from the different-induction time points were subjected to immunoblotting (IB) with antibodies as indicated in the figure. …”

TRLS2^-/- mice demonstrate appropriate hormone responses to low blood glucose. by Daniel W. Fisher (4872406)

“…<p><b>A)</b> Blood glucose was assessed at two time points in <i>Trls2</i>^+/+, <i>Trls2</i>^+/-, and <i>Trls2</i>^-/- mice, one hour after lights on (top graph) and an hour after lights off (bottom graph). …”

Effect of 500 bp C-terminal of TE deletion on virulence in the <i>F</i>. <i>monophora</i> infection mice model. by Minying Li (4477666)

“…<p>The conidia (1×10⁶) of all strains injected into the footpads of mice to infect mice. (A and B) The footpad thickness of mice were photographed and measured 3, 5, 7 and 14 days after infection. …”

Table1_Circulating erythroferrone has diagnostic utility for acute decompensated heart failure in patients presenting with acute or worsening dyspnea.docx by Sarah Appleby (15395237)

Data_Sheet_1_Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis.XLSX by Peng Nie (562100)

“…<p>Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide. …”

Systematic review of microRNAs in human acute kidney injury by Adrianna Douvris (4113439)

“…MicroRNAs (miRNAs) are implicated in AKI pathogenesis in preclinical models, but less is known about their role in humans. We conducted a systematic review to identify dysregulated miRNAs in humans with AKI.…”

Tick-Borne Encephalitis Virus Replication, Intracellular Trafficking, and Pathogenicity in Human Intestinal Caco-2 Cell Monolayers by Chao Yu (562804)

“…Immunofluorescence microscopy revealed co-localization of TBEV with early endosome antigen-1 (EEA1) as well as with sorting nexin-5 (SNX5), pointing to macropinocytosis as trafficking mechanism. …”

Data_Sheet_1_Predictors and Changes in Paternal Perinatal Depression Profiles—Insights From the DREAM Study.PDF by Susan Garthus-Niegel (3555482)

“…We found that rates of paternal depression symptoms decreased with 9% during pregnancy to 5% at 8 weeks postpartum. …”

Mitochondrial Superoxide Signaling Contributes to Norepinephrine-Mediated T-Lymphocyte Cytokine Profiles by Adam J. Case (232046)

“…Overall, these studies indicate that mitochondrial metabolism and O₂^●--mediated redox signaling play a regulatory role in the T-lymphocyte response to NE.…”

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx by Shubin Wang (3105348)

“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. …”

Genetic interaction analysis of <i>alfa-1</i>(<i>ok3062</i>) with <i>daf-2</i>(<i>e1370</i>) or <i>daf-16</i>(<i>mu86</i>). by Yon Ju Ji (3359057)

“…<p>(A) Brood size analysis of <i>alfa-1(ok3062)</i>. …”

Loss of <i>Smndc1</i> poison exon alters global transcript and protein abundance, while steady state RNA splicing is modestly affected. by Andrea E. Belleville (19434726)

“…Comparison between wild-type and <i>Smndc1</i> PE Δ/Δ mice. Red and blue points represent increased and decreased spliced isoforms in the poison exon null samples, respectively. …”

Supplementary file 1_Persistent burden and health inequalities of disease in women of childbearing age attributable to Intimate Partner Violence, 1990–2021.docx by Yingda Song (15410321)

“…Aims<p>Intimate Partner Violence (IPV) presents a significant global public health issue, particularly affecting women of childbearing age (WBCA). …”

Loss of <i>Nf1</i> results in reduced bone mineral density (BMD), volume (BV), and trabecular architecture in <i>Col2.3Cre⁺;Nf1^flox/−</i> mice <i>in vivo</i>.... by Xiaohua Wu (120920)

“…<p>BMD was measured with pDEXA scans at 8 weeks (<b>A</b>) (*p<0.05) and 24 weeks (<b>B</b>) (*p<0.05, **p<0.01). …”

Table1_High platelet adrenergic activity and concomitant activation of the pituitary/medullar axis as alarming laboratory parameters in ACS survivors—the STRESS-AMI study.docx by Zalán Gulyás (17999719)

“…Baseline aggregometry indicated platelet hyperactivity, decreasing gradually and being significantly reduced late, at 12 months (p < 0.05). …”

Data_Sheet_1_Altered Brain Structure in Chronic Visceral Pain: Specific Differences in Gray Matter Volume and Associations With Visceral Symptoms and Chronic Stress.pdf by Hanna Öhlmann (11584672)

“…Associations between visceral symptoms and GMV within frontal regions were altered in both patient groups, supporting a role of the central executive network across visceral pain conditions. …”

Table_1_Screening for potential warning biomarkers in cows with ketosis based on host–microbiota co-metabolism analysis.DOCX by Zhenlong Du (14063571)

“…Lithocholic acid in the plasma was a potential ketosis warning metabolite 7 days before delivery.…”

<i>Gambiense</i> Human African Trypanosomiasis and Immunological Memory: Effect on Phenotypic Lymphocyte Profiles and Humoral Immunity by Veerle Lejon (116133)

“…<div><p>In mice, experimental infection with <i>Trypanosoma brucei</i> causes decreased bone marrow B-cell development, abolished splenic B-cell maturation and loss of antibody mediated protection including vaccine induced memory responses. …”

Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress by Hammad, Ayat Samir

“…Background: Endoplasmic reticulum (ER) is the chief organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease (CKD). …”
Get full text