Table_1_Dual targeting of glutamine and serine metabolism in acute myeloid leukemia.xlsx by Kanwal M. Hameed (18386853)

“…Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant. …”

Supplementary Material for: Clinical Features and Long-Term Outcomes in 109 Pediatric Generalized Pustular Psoriasis by figshare admin karger (2628495)

“…The frequency and duration of flares showed a decreasing trend with increasing age. Earlier onset age is associated with a higher annual flare frequency. …”

DataSheet_1_Dual targeting of glutamine and serine metabolism in acute myeloid leukemia.pdf by Kanwal M. Hameed (18386853)

“…Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant. …”

DHA-induced apoptosis is caused by ROS. by Rui Kong (321043)

“…<p>(A) Apoptosis of pancreatic cancer cells. BxPC-3 and PANC-1 cells were treated with DHA (50 µmol/L) and Apo2L/TRAIL (100 ng/ml) as indicated. …”

Splenectomy Associated Changes in IgM Memory B Cells in an Adult Spleen Registry Cohort by Paul U. Cameron (210950)

“…Changes of asplenia in routine blood films including presence of Howell-Jolly bodies (HJB), occurred early (median 25 days) and splenectomy associated thrombocytosis and lymphocytosis peaked by 50 days. There was a more gradual decrease in IgM memory B cells reaching a stable level within 6 months after splenectomy. …”

Image_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.TIF by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

Video_1_Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro.MP4 by David Wegrzyn (10180829)

“…Interestingly, immunocytochemical staining of the PNN component Aggrecan revealed a clear disruption of PNNs accompanied by a significant increase of glutamatergic and a decrease of γ-aminobutyric acid-(GABA)ergic synapse numbers on PNN wearing neurons. …”

siRNA specific for human PVRL4 inhibits wtMV infections. by Ryan S. Noyce (208208)

“…(C) PVRL4 knockdown results in a decrease in wtMV titres in MCF7 and NCI-H358 cells. …”

<i>Mlh1</i> is required for striatal and liver <i>HTT</i> CAG repeat instability in B6.<i>Hdh^Q111/+</i> mice. by Ricardo Mouro Pinto (207712)

“…(B) Quantification of striatal and liver <i>HTT</i> CAG instability indices in these mice reveals a statistically significant decrease in <i>HTT</i> CAG instability in the absence of <i>Mlh1</i>. …”

Gal-3 upregulation in hypoxia depends on HIF-1α and NF-κB and is blocked by cicloheximide. by Rafael Yamashita Ikemori (698128)

“…Western blot analysis with the HIF-1αinhibitor demonstrated a slight decrease in gal-3 only in cells exposed to hypoxia, but not normoxia and CoCl₂, compared to DMSO control (experiment performed once). …”

The miR-181c inhibitor suppresses hESC differentiation. by Zhenyu Xu (105102)

“…<p>(A) Enforced expression of the miR-181c inhibitor down-regulated mature miR-181c levels relative to negative control (NC) RNA-transfected ESCs, as shown by qRT-PCR. **, p<0.01. …”

BRET² measurement of Gα_qβ₁γ₂ complex activation in HEK293 living cells expressing equal amounts of the WT of human TP receptor or its E1... by Valérie Capra (396007)

“…Agonist-induced coupling of TP receptor and Gq protein distances Gα_q-Rluc8 and GFP¹⁰-Gγ₂ giving rise to a decrease in the BRET signal. B. Protein expression levels of the constructs used for BRET experiments were set to be constant and able to assure the same level of basal BRET ratio in the presence of WT and E129V mutant of the human TP receptors. …”

Proteomic Analysis Reveals Novel Molecules Involved in Insulin Signaling Pathway by Yiguo Wang (2644723)

“…In addition, we also found that calcium/calmodulin-dependent protein serine kinase (CASK), a key protein in protein-targeting and vesicle transport in neurons, forms a complex with two unidentified phosphotyrosine proteins pp100 and pp95 in response to insulin-stimulation, though CASK is not itself tyrosine phosphorylated. …”

Proteomic Analysis Reveals Novel Molecules Involved in Insulin Signaling Pathway by Yiguo Wang (2644723)

“…In addition, we also found that calcium/calmodulin-dependent protein serine kinase (CASK), a key protein in protein-targeting and vesicle transport in neurons, forms a complex with two unidentified phosphotyrosine proteins pp100 and pp95 in response to insulin-stimulation, though CASK is not itself tyrosine phosphorylated. …”

Image_1_Altered gray matter structural covariance networks in drug-naïve and treated early HIV-infected individuals.PDF by Ruili Li (470065)

“…</p>Conclusion<p>Early HIV+ individuals exhibited a decrease in the efficiency of information transmission in sensory regions and a compensatory increase in the frontal lobe. …”

Overexpression of necdin ameliorates the motor axon outgrowth phenotype in <i>smn</i> morphant zebrafish. by Penelope J. Boyd (3936893)

“…Note the presence of the axonal outgrowth phenotype associated with <i>smn</i> knockdown (arrow heads) is reduced in the Ndn expressing animals. Scale bars = 50 μM. (D) Bar chart (mean & s.e.m.) showing a significant increase in the number of normal MNs, and a concomitant significant decrease in the number of severely affected MNs, in co-injected <i>smn</i> MO and Ndn mRNA embryos compared to single <i>smn</i> MO injected embryos at 30 hpf. …”

qRT-PCR primer sequences. by Fanchen Wang (8832908)

Image10_MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression.TIF by Xiang Li (114679)

S1 Raw data - by Fanchen Wang (8832908)

Primary antibody. by Fanchen Wang (8832908)